Changes in the use of chemoradiotherapy for non-small cell lung cancer after guideline implementation in Finland between 2016 and 2020 [0.03%]
芬兰在2016至2020年间指南实施后非小细胞肺癌患者化疗联合放疗使用变化情况调查
Viktor Wichmann,Tanja Skyttä,Pekka Mali et al.
Viktor Wichmann et al.
Background: Following treatment with chemoradiotherapy (CRT), approximately 30 % of patients with stage III unresectable non-small cell lung cancer (NSCLC) can achieve long-term remission with the possibility of a cure.[1...
Systemic therapy breakthroughs in the management of brain metastases: A new era for HER2-positive breast cancer [0.03%]
系统治疗在脑转移管理方面取得突破：HER2阳性乳腺癌进入新时代
Martina Parenza Arenhardt,Carolina Martins Vieira,Angélica Nogueira-Rodrigues
Martina Parenza Arenhardt
HER2-positive subtype accounts for 15-20 % of metastatic breast cancer (mBC) cases and is associated with a high incidence of brain metastases (BMs), which affects 35-50 % of the patients, contributing to poor outcomes. Although HER2-target...
Enhancing T cell infiltration in glioblastoma: a review article on challenges and therapeutic strategies [0.03%]
改善胶质母细胞瘤中T细胞浸润：挑战与治疗策略综述文章
Mohammad Amin Habibi,Negar Nejati,Majed Bahri Najafi et al.
Mohammad Amin Habibi et al.
This review focuses on enhancing T-cell infiltration in glioblastoma (GBM) while overcoming its immunosuppressive tumor microenvironment (TME). Key strategies include targeting myeloid-derived suppressor cells (MDSCs) to reduce immunosuppre...
Impact of adjuvant therapy on survival in treatment of CNS hemangiopericytomas [0.03%]
术后辅助治疗对中枢神经系统的血管周细胞瘤生存率的影响
Bharti Devnani,Subhash Gupta,Vibhay Pareek et al.
Bharti Devnani et al.
Introduction: Central nervous system (CNS) Hemangiopericytoma is a rare tumor which account for
Comprehensive pan-cancer analysis identified NSD2 as a potential prognostic and diagnostic biomarker [0.03%]
泛癌分析鉴定出NSD2作为潜在的预后和诊断生物标志物
Shuang Wang,Tao Li
Shuang Wang
NSD2 is a histone lysine N-methyltransferase that plays a crucial role in complex cancer biology. Despite mounting evidence highlighting the critical role of NSD2 in tumor progression and immunity, a comprehensive pan-cancer analysis of NSD...
The cognitive survivorship model: Bridging neuro-oncology and neurology [0.03%]
认知幸存者模型：神经肿瘤学和神经病学的桥梁
Sahar Hemeda,Mohammed Elmadani,József Janszky et al.
Sahar Hemeda et al.
Cognitive impairment is a prevalent yet often overlooked consequence of cancer and neurodegenerative diseases, substantially impacting the quality of life, daily functioning, and emotional well-being of affected individuals. Despite differi...
Prognostic value of FBXW7 tumor suppressor gene expression and mutations in patients with colorectal cancer: A meta-analysis [0.03%]
FBXW7抑癌基因表达和突变在结直肠癌患者预后价值的荟萃分析
Mohammad Rahmanian,Iman Elahi Vahed,Mohammad Shirali et al.
Mohammad Rahmanian et al.
Background: Colorectal cancer (CRC) ranks as the second most common cause of cancer-related mortality globally. The tumor suppressor gene FBXW7 is considered to play a key role in determining patient prognosis. This study...
Rationale and design of the PAMSARC (pasireotide as maintenance treatment with monthly deep intramuscular injection in SSTR2/3/5-expressing synovial sarcoma and desmoplastic small round cell tumor) multicenter phase 2 trial [0.03%]
PAAMSARC（替柳西肽作为SSTR2/3/5阳性滑膜肉瘤和间叶性小圆细胞瘤维持治疗的每月深层肌肉注射）多中心二期临床试验的设计与原理
Christoph E Heilig,Christoph Heining,Editha Gnutzmann et al.
Christoph E Heilig et al.
Background: Desmoplastic small round cell tumor (DSRCT) and synovial sarcoma (SySa) are rare cancers primarily affecting adolescents and young adults. Prognosis is generally poor, particularly upon metastasis, due to limi...
Recent advances in targeted prostate cancer diagnosis and therapy using ultrasound imaging combined with novel nanocarriers:facilitating early detection and effective treatment of prostate cancer [0.03%]
结合超声成像与新型纳米载体的靶向前列腺癌诊断及治疗的研究进展：促进前列腺癌的早期检测和有效治疗
Hannian Kang,Mingqiu Hu
Hannian Kang
Prostate cancer represents the second most prevalent malignancy among males globally, exhibiting a significantly lower 5-year survival rate in China relative to Western nations. Early diagnosis constitutes a critical factor in enhancing cli...
Comparing the oncologic outcomes of breast-conserving surgery for breast cancer patients performed either upfront or following neoadjuvant chemotherapy: a matched retrospective cohort [0.03%]
乳房保守手术治疗乳腺癌患者在新辅助化疗前与后的肿瘤结局比较：基于匹配病例队列的研究
Hazem Assi,Malak Ghezzawi,Hussein Nassar et al.
Hazem Assi et al.
Background: Neoadjuvant chemotherapy (NACT) is used to reduce breast cancer size before surgery, allowing for breast conservation surgery (BCS) instead of mastectomy. However, concerns exist about higher positive margins ...