Identification of SARS2, PKN1, and IL11RA as causally-associated genes for patients with gastric cancer via immune cell activity: A multi-omics Mendelian randomization study integrating GWAS, eQTL, and pQTL data [0.03%]
通过免疫细胞活性识别SARS2、PKN1和IL11RA作为胃癌患者因果相关基因的多组学孟德尔随机化研究：整合GWAS、eQTL和pQTL数据
Chenhao Tang,Zekai Zhou,Hui Jiang et al.
Chenhao Tang et al.
Background: Gastric cancer (GC) is a highly heterogeneous gastrointestinal malignancy associated with poor prognosis. A comprehensive understanding of its molecular mechanisms is crucial for identifying novel therapeutic ...
Thaysa Ghiarone,Emily Hansen,James M Holaska
Thaysa Ghiarone
Nuclear dysmorphism is a critical indicator of tumor aggressiveness, influencing cancer cell invasion and metastasis. Emerin, an integral nuclear envelope protein involved in nuclear architecture, is important for maintaining nuclear integr...
Oxaliplatin and/or gemcitabine vs. FOLFIRINOX in first-line Advanced pancreatic adenocarcinoma: Real-world efficacy and safety data of moroccan patients [0.03%]
奥沙利铂和/或吉西他滨与FOLFIRINOX作为一线药物治疗晚期胰腺导管腺癌的疗效及安全性：摩洛哥患者的现实世界数据
Hassan Abdelilah Tafenzi,Youssef Ait Takniouine,Ismail Essadi et al.
Hassan Abdelilah Tafenzi et al.
Background: While fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) offers a survival advantage in advanced pancreatic adenocarcinoma (PAC) compared to gemcitabine, gemcitabine-oxaliplatin, and gemcitabin...
Investigating the quality of sexual function in women with genital cancers: A structural equation analysis approach [0.03%]
女性生殖系统癌症患者性功能质量调查：结构方程分析方法
Sara Moradi,Parvin Hassanzadeh,Mahsa Kahrobaie et al.
Sara Moradi et al.
Background: Genital cancers significantly impair women's quality of life, with sexual dysfunction as a common yet under-addressed issue. Most studies use univariate analyses and lack a comprehensive model of the multifact...
Partial nephrectomy Vs. Percutaneous thermal ablation of small renal masses [0.03%]
小型肾肿瘤的局部切除与经皮热消融疗法
Ofer N Gofrit,Liat Appelbaum Pikarsky,S Nahum Goldberg et al.
Ofer N Gofrit et al.
Background: Percutaneous thermal ablation (TA), partial nephrectomy (PN), and active surveillance with delayed intervention in tumors smaller than 3 cm are the recommended treatments for small renal masses (SRMs). In this...
Validation of the pheochromocytoma of adrenal gland scaled score (PASS) grading system: A retrospective double-centered cross-sectional study [0.03%]
肾上腺嗜铬细胞瘤评分系统（PASS）的验证研究：一项回顾性的双中心横断面研究
Maha Ahmad Faraman,Ammar Albostani,Rufaida Ahmad Faraman et al.
Maha Ahmad Faraman et al.
Background: Pheochromocytomas are adrenal medullary tumors with unpredictable malignant potential. The Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) stratifies risk based on histology, but its reliability is d...
3-month postoperative efficacy evaluation of CT-guided 125I seed implantation treatment for intracranial tumors: A double-center retrospective analysis [0.03%]
CT引导下125碘粒子植入治疗颅内肿瘤的疗效评价：为期3个月的双中心回顾性分析
Xuesong Li,Cheng Zhao,Dan Xu et al.
Xuesong Li et al.
Purpose: To explore the changes in tumor volume, midline shift, and edema at three months post-surgery of CT-Guided 125I radioactive seed implantation for intracranial tumors. ...
P K Jha,Bipin Chaurasia
P K Jha
Surgical removal of meningioma sometimes become challenging due to its nature of slow growing and being huge at the time of diagnosis. Another problems exists when it becomes adhere to critical structures posing threat to post -op neurologi...
Ehsan Kianfar,Alaa M Alrudainy,Ayoob Radhi Al-Zaalan et al.
Ehsan Kianfar et al.
One promising target for creating new anticancer medications is phosphatidyl-inositol-3-kinase (PI3K). Many human malignancies, including brain, colon, endometrial, breast, and prostate cancers, have been linked to PI3K dysregulation. The g...
Murtaza Jafari,Shaiyar Shahryar,Sohameh Mohebbi et al.
Murtaza Jafari et al.
Cancer remains a major global health burden; consequently, the development of more effective and less toxic treatment options is paramount. DNA nanostructures are a promising platform for cancer therapy harnessing the unique properties of D...