The role of telomerase and viruses interaction in cancer development, and telomerase-dependent therapeutic approaches [0.03%]
端粒酶与病毒相互作用在癌症发生中的作用及端粒酶依赖的治疗手段
Ali Salimi-Jeda,Fariba Badrzadeh,Maryam Esghaei et al.
Ali Salimi-Jeda et al.
Human telomerase reverse transcriptase (hTERT) is an enzyme that is critically involved in elongating and maintaining telomeres length to control cell life span and replicative potential. Telomerase activity is continuously expressed in hum...
Abhishek Gangopadhyay,Kunal Nandy,Ketul Puj et al.
Abhishek Gangopadhyay et al.
Introduction: Primary chest wall sarcoma is a rare entity. It can be classified based on its origin, as bone sarcomas or soft tissue sarcomas. Various prognostic factors have been studied in different case series like age...
Osteosarcoma, personalized medicine, and tissue engineering; an overview of overlapping fields of research [0.03%]
骨肉瘤、个体化医疗和组织工程；概述了研究领域的重叠部分
Azam Bozorgi,Leila Sabouri
Azam Bozorgi
Introduction: Osteosarcoma is a common bone malignancy in patients of all ages. Surgical and chemotherapy interventions fail to shrink tumor growth and metastasis. The development of efficient patient-specific therapeutic...
Body composition and metastatic prostate cancer survivorship [0.03%]
体力和转移性前列腺癌幸存者ship并没有一个明确的中文词汇可以直译，根据语境推测，这里可能是指前列腺癌患者的生存状况或生存质量。因此，更合理的翻译应该是：“体质组成与转移性前列腺癌患者的生存质量”
Adriana M Coletta,Nicolas Sayegh,Neeraj Agarwal
Adriana M Coletta
There is a growing body of evidence related to the importance of body composition in cancer survivorship. Current evidence exclusive to the metastatic prostate cancer setting is limited, yet sheds light on the importance of body composition...
High expression of ACE2 in HER2 subtype of breast cancer is a marker of poor prognosis [0.03%]
HER2亚型乳腺癌中ACE2高表达是预后不良的标志
Madhumathy G Nair,Jyothi S Prabhu,Sridhar Ts
Madhumathy G Nair
Background: ACE2 a key molecule of the Renin-Angiotensin system has been identified as the receptor for SARS-CoV-2 entry into human cells. In the context of human cancers, there is evidence that ACE2 might function as a t...
AR-V7 biomarker testing for primary prostate cancer: The ongoing challenge of analytical validation and clinical qualification [0.03%]
前列腺癌AR-V7生物标志物检测：分析验证和临床确认的挑战
Adam G Sowalsky,Adam Sharp,Shana Y Trostel et al.
Adam G Sowalsky et al.
Revisiting a lower starting dose of alectinib in ALK-Positive non-small cell lung cancer [0.03%]
重议用于ALK阳性非小细胞肺癌患者的brigatinib较低起始剂量疗法
Danielle Benedict Sacdalan,Josephine Anne Lucero
Danielle Benedict Sacdalan
We present here a case of ALK-positive lung adenocarcinoma that has been started on Alectinib. Treatment has been initiated at the recommended initial dose, but it subsequently required a dose adjustment following adverse drug events. Alect...
Adjuvant platinum-based chemotherapy in non-small cell lung cancer: The role of relative dose-intensity and treatment delay [0.03%]
非小细胞肺癌辅助以铂类为基础的化疗：相对剂量强度和治疗延迟的作用
W M Szejniuk,M Cekala,M Bøgsted et al.
W M Szejniuk et al.
Background: The study investigated the association of the relative dose-intensity (RDI) of cisplatin and timing of adjuvant platinum-based chemotherapy (APC) with survival for stage I-III non-small cell lung cancer (NSCLC...
Syndecans in cancer: A review of function, expression, prognostic value, and therapeutic significance [0.03%]
癌细胞中 syndecan 的功能、表达、预后价值和治疗意义综述
Daniel Czarnowski
Daniel Czarnowski
While our understanding of tumors and how to treat them has advanced significantly since the days of Aminopterin and the radical mastectomy, cancer remains among the leading causes of death worldwide. Despite innumerable advancements in med...
Amany I Alqosaibi,Shaimaa Abdel-Ghany,Hussein Sabit
Amany I Alqosaibi
Cancer is the second leading cause of death globally, where nearly 1 in 6 deaths is due to cancer, with 70% of all deaths from cancer occur in low- and middle-income countries. The overall lifetime risk of developing colorectal cancer is 1 ...