Clinical significance of immunocyte- and ferroptosis-related markers for the prognosis of patients with tenosynovial giant cell tumor: A cross-sectional study [0.03%]
免疫细胞和铁死亡相关标志物对滑膜巨细胞瘤预后意义的横断面研究
Zhi-Qiang Song,Yesitai Saierhali,Chen-Xi Li et al.
Zhi-Qiang Song et al.
Background: Tenosynovial giant cell tumor (TGCT) comprises localized (L-TGCT) and diffuse (D-TGCT) subtypes, but how ferroptosis regulators, tumor-associated immune-cell markers and proliferation indices jointly relate to...
Pegfilgrastim versus filgrastim for chemo-mobilized stem cell collection in multiple myeloma: A retrospective real-world study [0.03%]
PEG-rhG-CSF与rhG-CSF在多发性骨髓瘤化疗动员干细胞采集中的疗效比较:一项回顾性真实世界研究
Yan-Lin Zhang,Xin-Yi Qin,Chun Cao et al.
Yan-Lin Zhang et al.
Background: Autologous stem cell transplantation (ASCT) is a standard treatment for newly diagnosed multiple myeloma (MM). Achieving sufficient stem cell yield via effective mobilization promotes successful hematological ...
Advances in the management of small cell lung cancer: thoracic and cranial radiation therapy and sequencing with systemic therapy [0.03%]
小细胞肺癌的治疗进展:胸部和颅脑放疗及系统化疗的序贯治疗方法
Dionee Liefman,Margot Lehman
Dionee Liefman
Small cell lung cancer (SCLC) is a highly aggressive malignancy that is characterised by rapid proliferation and early metastatic dissemination. This review outlines the advances in management strategies for very limited-stage (VLS-SCLC), l...
Normal kidney tissue derived extracellular vesicles suppress clear cell renal cell carcinoma progression via transfer their inhibitory miRNAs [0.03%]
正常肾组织来源的外泌体通过转移其抑制性miRNA来抑制透明细胞肾细胞癌的发展进展
Liqun Huang,Huaru Zhang,Zhiguo Chen et al.
Liqun Huang et al.
Tumor-derived extracellular vesicles (EVs) contribute to tumor progression and metastasis. We recently reported that EVs derived from normal kidney tissues (N-EVs) suppress sterile cardiac inflammation in myocardial ischemic injury models. ...
The association of glucose disposal rate on cancer odds mediated by composite inflammatory biomarkers: a cross-sectional study [0.03%]
糖处置率与癌症发生率相关性及其通过多种炎症生物标志物介导的交叉-sectional研究
Yingzhe Zhang,Jiaxiang Yang,Guangming Fu et al.
Yingzhe Zhang et al.
Background: Existing studies have demonstrated a close association between diabetes mellitus and the occurrence and progression of tumors; however, the impact of estimated glucose disposal rate (eGDR) on cancer odds in th...
Tolerability and effectiveness of definitive chemoradiotherapy in locally advanced lung cancer patients with combined pulmonary fibrosis and emphysema [0.03%]
局部晚期肺癌伴发肺气肿和间质纤维化患者根治性同期放化疗的耐受性和有效性分析
Kana Fujimoto,Mariko Kogo,Hisato Kobayashi et al.
Kana Fujimoto et al.
Background: This study evaluated the efficacy and safety of definitive chemoradiotherapy (CRT) for lung cancer in patients with combined pulmonary fibrosis and emphysema (CPFE), focusing on radiation pneumonitis (RP). ...
CRI-CCTG-0003/IND.240 an immunotherapy platform study in platinum-resistant high grade serous ovarian cancer (IPROC): Sub-studies A and B: Durvalumab (D) + mecbotamab vedotin (BA3011) or ozuriftamab vedotin (BA3021) [0.03%]
CIK-CCMTG-0003/IND.240:铂耐药型高级别浆液性卵巢癌免疫治疗平台研究(IPROC)第二阶段A部分和B部分研究:度伐利尤单抗联合美博妥珠单抗(BA3011)或奥佐妥珠单抗(BA3021)
Helen J MacKay,Anna V Tinker,Brad H Nelson et al.
Helen J MacKay et al.
Objective: IPROC is an ongoing platform trial investigating novel immunotherapy combinations in platinum resistant high grade serous ovarian cancer. Here we report on the combination of durvalumab with two conditionally a...
RPL32: From housekeeping gene to potential biomarker and therapeutic target in cancer and multiple system diseases [0.03%]
RPL32:从管家基因到癌症和多系统疾病中的潜在生物标志物和治疗靶点
Fangju Huang,Gang Chen,YiWu Dang et al.
Fangju Huang et al.
Ribosomal protein L32 (RPL32) is a core component of the 60S ribosomal subunit and a stable reference gene. Mounting evidence shows that RPL32 is upregulated in hepatocellular carcinoma, lung cancer, breast cancer, prostate cancer, and othe...
Immunotoxin therapy: a promising frontier in targeted cancer treatment a review of clinical trials in hematological and solid tumors [0.03%]
免疫毒素疗法:一项针对癌症的精准治疗前沿策略——血液系统和实体肿瘤临床试验回顾
Arash Abdi,Hamid Sedighian,Zoleikha Goleij et al.
Arash Abdi et al.
Background and objective: Background and objective: Cancer is a leading cause of death worldwide, creating a major socioeconomic burden. Despite advances in conventional therapies, mortality remains high, highlighting the...
Concurrent monomorphic epitheliotropic intestinal T-cell lymphoma with aberrant CD20 expression and lung adenocarcinoma: A case report and literature review [0.03%]
伴有CD20异常表达的单克隆上皮细胞肠T细胞淋巴瘤合并肺腺癌一例及文献复习
Ying Wang,Sha Ma,Xiaoqian Li et al.
Ying Wang et al.
Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare and aggressive subtype of intestinal T-cell lymphoma with a dismal prognosis. MEITL with aberrant CD20 expression is even rarer. To date, there have been no reported c...