Pathogenic diversity of Cryptococcus in Galleria mellonella extends beyond classical virulence factors [0.03%]
鼻孢子菌素在大蜡螟中的致病多样性超出了经典毒力因素的作用
Bianca A G Sena,Marlon D M Santos,Cassia M Souza et al.
Bianca A G Sena et al.
Pathogenic determinants in the Cryptococcus genus have been extensively studied, often using standard laboratory isolates. Here, we analyzed the virulence of ten Cryptococcus isolates from diverse sources, species, and genotypes. These isol...
Growth conditions shape the proteome and diversity of Neurospora crassa extracellular vesicles [0.03%]
营养条件影响嗜渗枯草芽胞杆菌细胞外囊泡的蛋白质组及多样性
Daniel A Salgado-Bautista,Meritxell Riquelme
Daniel A Salgado-Bautista
Extracellular vesicles (EVs) are nanosized, lipid bilayer-enclosed particles secreted by all living organisms. While EV research has primarily focused on mammalian systems, fungal EVs are gaining attention for their biological significance....
Localization characteristics of cell wall synthesis protein Wag31 and penicillin binding protein C in Clavibacter michiganensis [0.03%]
Clavibacter michiganensis中细胞壁合成蛋白Wag31和青霉素结合蛋白C的定位特征
Chengxuan Yu,Xiaoli Xu,Jia Shi et al.
Chengxuan Yu et al.
CmWag31 is a member of the DivIVA family of proteins in Clavibacter michiganensis. The DivIVA family have been demonstrated to play a key role in the synthesis of cell wall peptidoglycan and cell division in most bacterial species. It has b...
Innate immune recognition of Mycobacterium tuberculosis: receptor engagement and inflammatory outcomes at the site of infection [0.03%]
结核分枝杆菌感染部位的固有免疫识别：受体结合和炎症反应
N E Mvubu
N E Mvubu
M. tuberculosis is a notorious global pathogen responsible for over a million fatalities annually. It has been estimated that one-third of the world's population is latently infected with M. tuberculosis; however, only ∼10 million individu...
Bacteriophages as an alternative strategy for the treatment of drug resistant bacterial infections: Current approaches and future perspectives [0.03%]
噬菌体作为治疗药物耐受性细菌感染的替代策略：当前方法与未来展望
Abayeneh Girma
Abayeneh Girma
A persistent increase in antimicrobial resistance presents a significant danger to global public health. The application of bactericidal phages that do not interfere with the body's natural flora becomes a promising approach to alternative ...
Immunomodulatory function of chitosan is dependent on complement receptor 3 [0.03%]
壳聚糖的免疫调节功能依赖于补体受体3
Jeanette Wagener,Xiaowen Wang,Katharina L Becker et al.
Jeanette Wagener et al.
Chitosan, the deacetylated product of chitin, is a significant component of the cell walls of nearly all fungi. In contrast with the high level of attention paid to plant immune recognition of chitin and chitosan of plant pathogenic fungi w...
Paul Vogel,Staffan Persson,Guillermo Moreno-Pescador et al.
Paul Vogel et al.
Plants sense their environment at the cell surface, i.e. the plasma membrane, where extracellular signals are perceived and transduced. Together with the cortical cytoskeleton and the cell wall, membrane lipids can influence these processes...
Temperature-dependent regulation of bacterial cell division hydrolases by the coordinated action of a regulatory RNA and the ClpXP protease [0.03%]
一个调控性RNA和ClpXP蛋白酶的协同作用通过温度依赖方式调节细菌细胞分裂水解酶活性
Viktor H Mebus,Larissa M Busch,Morten Børre et al.
Viktor H Mebus et al.
A defining feature of bacteria is the peptidoglycan cell wall which provides structural integrity and prevents osmotic lysis. While peptidoglycan hydrolases are required for daughter cell separation, dysregulated cell wall degradation may r...
Virtual screening of a random tripeptide library for easily prepared inhibitors of insect chitinolytic enzymes [0.03%]
昆虫几丁质酶易合成抑制剂的虚拟筛选及三肽随机文库的研究
Zihan Pang,Yi Ding,Huijie Xie et al.
Zihan Pang et al.
Insect molting requires chitinolytic enzymes to hydrolyze the chitin in the old cuticle, making chitinolytic enzyme inhibitors potential insecticides. Naturally occurring peptide chitinase inhibitors, such as argadin and argifin, possess co...
Peptides in plant-microbe interactions: Functional diversity and pharmacological applications [0.03%]
植物微生物互作中的肽类：功能多样性及药用前景
Minghui Song,Yunbing Zhou,Gang Li et al.
Minghui Song et al.
As dynamic interfaces governing molecular recognition and signal transduction, interactions between plants and microbes fundamentally shape ecosystem dynamics and evolutionary trajectories. This review summarizes peptides involved in plant-...