Infigratinib (BGJ398) in previously treated patients with advanced or metastatic cholangiocarcinoma with FGFR2 fusions or rearrangements: mature results from a multicentre, open-label, single-arm, phase 2 study [0.03%]
FGFR2融合或重排的先前治疗的晚期或转移性胆管癌患者中Infigratinib(BGJ398)的疗效：一项多中心，开放标签，单臂II期试验的成熟结果
Milind Javle,Sameek Roychowdhury,Robin Kate Kelley et al.
Milind Javle et al.
Background: Treatment options are sparse for patients with advanced cholangiocarcinoma after progression on first-line gemcitabine-based therapy. FGFR2 fusions or rearrangements occur in 10-16% of patients with intrahepat...
Infigratinib in pretreated cholangiocarcinoma with FGFR2 fusions or rearrangements [0.03%]
用于治疗携带FGFR2融合或重排的胆管癌患者的infigratinib疗法
Cindy Neuzillet
Cindy Neuzillet
The impact of COVID-19 on hepatitis services and civil society organisations [0.03%]
COVID-19对肝炎服务和民间社会组织的影响
Chris Wingrove,Cary James,Su Wang
Chris Wingrove
The economic burden of colorectal cancer across Europe: a population-based cost-of-illness study [0.03%]
欧洲范围内结直肠癌的经济负担：一项基于人口的疾病负担研究
Raymond Hugo Henderson,Declan French,Timothy Maughan et al.
Raymond Hugo Henderson et al.
Background: Colorectal cancer is one of the leading causes of cancer morbidity and mortality in Europe. We aimed to ascertain the economic burden of colorectal cancer across Europe using a population-based cost-of-illness...
Maarten J IJzerman
Maarten J IJzerman
Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled trial [0.03%]
基于深度学习的系统对上消化道内镜检查中胃肿瘤漏检率影响的单中心序贯随机对照试验
Lianlian Wu,Renduo Shang,Prateek Sharma et al.
Lianlian Wu et al.
Background: White light endoscopy is a pivotal first-line tool for the detection of gastric neoplasms. However, gastric neoplasms can be missed during upper gastrointestinal endoscopy due to the subtle nature of these les...
Randomized Controlled Trial
The lancet. Gastroenterology & hepatology. 2021 Sep;6(9):700-708. DOI:10.1016/S2468-1253(21)00216-8 2021
Early detection of gastric neoplasia: is artificial intelligence the solution? [0.03%]
人工智能能够解决早期胃肿瘤诊断问题吗？
Omer F Ahmad
Omer F Ahmad
Thomas Marjot,David W Ray,Felicity R Williams et al.
Thomas Marjot et al.
Sleep is a complex, highly regulated process essential for human health and wellbeing. Increasingly, sleep-wake disturbance has been implicated in the pathogenesis of chronic liver disease, particularly the development and progression of no...
The role of precision nutrition in the modulation of microbial composition and function in people with inflammatory bowel disease [0.03%]
精确营养在炎症性肠病患者肠道微生物组调节中的作用
Alexa N Sasson,Richard J M Ingram,Zhengxiao Zhang et al.
Alexa N Sasson et al.
Inflammatory bowel diseases, principally Crohn's disease and ulcerative colitis, are multifactorial chronic conditions. Alterations in gut microbial patterns partly affect disease onset and severity. Moreover, the evolution of dietary patte...
Incorporating fatty liver disease in multidisciplinary care and novel clinical trial designs for patients with metabolic diseases [0.03%]
代谢性疾病患者的多学科护理和新颖临床试验设计中纳入脂肪肝病
Mohammed Eslam,Aijaz Ahmed,Jean-Pierre Després et al.
Mohammed Eslam et al.
With the global epidemics of obesity and associated conditions, including type 2 diabetes, metabolic dysfunction-associated fatty liver disease, chronic kidney disease, hypertension, stroke, cardiovascular disease, osteoporosis, cancer, and...