Effect of gluten and wheat on symptoms and behaviours in adults with irritable bowel syndrome: a single-centre, randomised, double-blind, sham-controlled crossover trial [0.03%]
无麸质和无小麦饮食对肠易激综合征成人患者症状和行为的影响：单中心随机双盲对照交叉试验
Caroline Larissa Seiler,Gaston Horacio Rueda,Pedro Miguel Miranda et al.
Caroline Larissa Seiler et al.
Background: Many patients with irritable bowel syndrome (IBS) believe gluten or wheat triggers their symptoms. We compared symptomatic responses to wheat and gluten with gluten-free sham challenge in patients with IBS who...
Anti-TL1A antibody, afimkibart, in moderately-to-severely active ulcerative colitis (TUSCANY-2): a multicentre, double-blind, treat-through, multi-dose, randomised, placebo-controlled, phase 2b trial [0.03%]
乌菜克比巴特（抗TL1A单克隆抗体）治疗中至重度溃疡性结肠炎的二期临床试验：TUSCANY-2研究是一项多中心、双盲、疗效持续评估直至病情缓解或出现预设终点的随机安慰剂对照试验
Silvio Danese,Jessica R Allegretti,Stefan Schreiber et al.
Silvio Danese et al.
Background: TNF-like ligand 1A (TL1A) is an emerging therapeutic target for inflammatory bowel disease. We evaluated the safety and efficacy of multiple doses of afimkibart, a TL1A-directed antibody, in patients with mode...
Intraoperative fluorescence angiography with indocyanine green to prevent anastomotic leak in rectal cancer surgery (IntAct): an unblinded randomised controlled trial [0.03%]
荧光血管造影法用于直肠癌手术中预防吻合口瘘的院内靛氰绿试验（IntAct）：一项开放性随机对照试验
David Jayne,Julie Croft,Neil Corrigan et al.
David Jayne et al.
Background: Data are mixed on whether indocyanine green (ICG) fluorescence angiography can reduce the high rate of anastomotic leaks in patients undergoing surgery for rectal cancer. Therefore, we aimed to investigate the...
Stine Johansen,Fredrik Åberg,Emmanuel A Tsochatzis et al.
Stine Johansen et al.
Steatotic liver disease often progresses asymptomatically, with the risk of advancing to cirrhosis and liver cancer. Early detection of advanced liver disease through screening presents an opportunity to prevent severe outcomes, if said scr...
Temporal trends in hepatitis C incidence among people tested more than once in Georgia, 2017-23: a nationwide, retrospective cohort [0.03%]
2017-2023年乔治亚州重复检测人群的丙型肝炎发病率趋势：全国性回顾队列研究
Davit Baliashvili,Shaun Shadaker,Nathan Furukawa et al.
Davit Baliashvili et al.
Background: Achieving low incidence is one of WHO's key targets for the elimination of hepatitis C virus (HCV) infection. As progress in Georgia's hepatitis C elimination programme moves the country closer to reaching thi...
Carina Venter,Heidi M Staudacher
Carina Venter
Clinical success after peroral endoscopic myotomy in the context of reflux-related symptoms [0.03%]
内镜下肌切开术治疗与反流相关症状的临床疗效评估
Yasutoshi Shiratori,Anthony Kalloo
Yasutoshi Shiratori