Lessons learned from the BOSS trial: new directions in Barrett's oesophagus [0.03%]
BOSS试验的教训：巴雷特食管的新方向
Rebecca C Fitzgerald,Peter Sasieni
Rebecca C Fitzgerald
Primary biliary cholangitis and the narrowing gap towards optimal disease control [0.03%]
原发性胆汁性胆管炎：通往理想疾病控制的路途中狭窄的缺口正逐步缩小
Guilherme Grossi Lopes Cançado,Ana Lleo,Cynthia Levy et al.
Guilherme Grossi Lopes Cançado et al.
Although infrequent, primary biliary cholangitis is not indolent and remains a burdensome chronic autoimmune biliary disease. Progressive biliary injury and cholestasis results in complications of biliary cirrhosis, with reduced quality and...
Pre-emptive TIPS for gastric variceal bleeding: an important first step but a long way to go [0.03%]
胃静脉曲张出血的预防性TIPS：重要的第一步，但还有很长的路要走
Michael Praktiknjo,Jonel Trebicka
Michael Praktiknjo
Pre-emptive TIPS for gastric variceal bleeding in patients with cirrhosis (GAVAPROSEC): an open-label randomised clinical trial [0.03%]
预防性使用TIPS治疗肝硬化患者胃静脉曲张出血(GAVAPROSEC)：一项开放标签随机临床试验
Jean-Paul Cervoni,Delphine Weil,Maxime Desmarets et al.
Jean-Paul Cervoni et al.
Background: In patients with cirrhosis, variceal glue obliteration is recommended for the treatment of acute fundal variceal bleeding, and for the prevention of rebleeding in combination with non-selective β blockers (NS...
Faecal incontinence core outcome set: an international Delphi consensus exercise among patients, health-care professionals, and researchers [0.03%]
Sadé L Assmann,Daniel Keszthelyi,Merel L Kimman et al.
Sadé L Assmann et al.
Faecal incontinence is a debilitating anorectal disorder that can severely affect a person's quality of life. The variability in reported outcomes in studies on treatments for faecal incontinence complicates the synthesis of evidence, there...
A new endoscopic paradigm: evaluating the EASE-CD score for Crohn's disease [0.03%]
新的内镜模式：评估克罗恩病的EASE-CD评分系统
Yoram Bouhnik,Jean Yves Mary
Yoram Bouhnik
Development and validation of a novel Endoscopic ulcer Activity Score for Evaluation of Crohn's Disease (EASE-CD) using data from two randomised controlled trials [0.03%]
内镜溃疡活动评分(EASE-CD)的开发和验证：两项随机对照试验数据的使用
Christopher Ma,Reena Khanna,Bryan R Maguire et al.
Christopher Ma et al.
Background: Endoscopy is essential for measuring luminal disease activity in Crohn's disease. Existing indices for evaluating endoscopic Crohn's disease activity are only modestly correlated with clinical disease activity...
Efimosfermin alfa (BOS-580), a long-acting FGF21 analogue, in participants with phenotypic metabolic dysfunction-associated steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2a trial [0.03%]
Efimosfermin alfa（BOS-580）治疗表型代谢紊乱相关脂肪肝病患者的疗效和安全性：一项多中心、随机、双盲、安慰剂对照的Ⅱa期临床试验
Rohit Loomba,Kris V Kowdley,Jose Rodriguez et al.
Rohit Loomba et al.
Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease characterised by steatosis, inflammation, and liver fibrosis. Efimosfermin alfa (efimosfermin, formerly BOS-580) is a long-actin...
GLP-1 receptor agonists in alcohol use disorder and alcohol-associated liver disease [0.03%]
葡萄糖依赖性促胰岛素多肽受体激动剂在酒精使用障碍和酒精相关肝病中的应用
Ashwani K Singal,Lorenzo Leggio
Ashwani K Singal