Zaira Spinello,Zein Mersini Besharat,Fabrizio Mainiero et al.
Zaira Spinello et al.
MicroRNAs (miRNAs) are small non-coding RNAs that act as critical regulators of gene expression by repressing mRNA translation. The role of miRNAs in cell physiology spans from cell cycle control to cell proliferation and differentiation, b...
LncRNA APTR amplification serves as a potential glioma biomarker and promotes glioma progression via miR-6734-5p/ TCF7/LEF1 axis [0.03%]
长链非编码RNA APTR扩增作为潜在的胶质瘤生物标志物并通过miR-6734-5p/ TCF7/LEF1轴促进胶质瘤进展
Heng Chen,Mengzhen Huang,Jiayi Li et al.
Heng Chen et al.
Background: Alu-mediated p21 transcriptional regulator (APTR) overexpression is detected in different human cancers; however, few reports have investigated APTR gene amplification conditions. Furthermore, whether APTR amp...
PD-L1 pfeRNAs as blood-based predictors of treatment response of unresectable malignant pleural mesothelioma patients administered Durvalumab with cisplatin and pemetrexed as first-line therapy [0.03%]
不可切除的恶性胸膜间皮瘤患者使用Durvalumab联合顺铂和培美曲塞作为一线治疗的疗效预测的血液标志物PD-L1 pfeRNAs
Andrei Gurau,Suguru Yamauchi,Kaitlyn Ecoff et al.
Andrei Gurau et al.
Background: A new therapeutic avenue combining Durvalumab with cisplatin-pemetrexed (Durva-CP) has delivered a promising outcome for previously untreated patients with unresectable malignant pleural mesothelioma (MPM) in ...
miR-210 overexpression increases pressure overload-induced cardiac fibrosis [0.03%]
miR-210过表达增加压力超负荷引起的的心肌纤维化
G Zaccagnini,D Baci,S Tastsoglou et al.
G Zaccagnini et al.
Aortic stenosis, a common valvular heart disease, can lead to left ventricular pressure overload, triggering pro-fibrotic responses in the heart. miR-210 is a microRNA that responds to hypoxia and ischemia and plays a role in immune regulat...
MicroRNA-541-3p/Rac2 signaling bridges radiation-induced lung injury and repair [0.03%]
microRNA-541-3p/Rac2信号在辐射诱导的肺损伤和修复中充当桥梁作用
Jiandong Zhang,Lei Ma,Limin He et al.
Jiandong Zhang et al.
Background: While radiation-induced lung injury decreases quality of life and suppresses efficacy of radiotherapy, to date, the relationship between radiation-induced lung injury and repair remains unclear. Our previous s...
LURAP1L-AS1 long noncoding RNA promotes breast cancer progression and associates with poor prognosis [0.03%]
长非编码RNA LURAP1L-AS1促进乳腺癌进展并与预后不良有关
Radhakrishnan Vishnubalaji,Dania Awata,Nehad M Alajez
Radhakrishnan Vishnubalaji
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of cancer biology, yet their roles in breast cancer, particularly in triple-negative breast cancer (TNBC), remain incompletely understood. Through a custom siRNA library scre...
Long non-coding RNAs in humans: Classification, genomic organization and function [0.03%]
人类中的长非编码RNA：分类，基因组组织和功能
Barbara Chodurska,Tanja Kunej
Barbara Chodurska
Long non-coding RNAs (lncRNAs) regulate numerous biological functions in animals. Despite recent advances in lncRNA research, their structural and functional annotation and classification remain an ongoing challenge. This review provides a ...
Research progress on the interaction between intestinal flora and microRNA in pelvic inflammatory diseases [0.03%]
盆腔炎性疾病相关肠道菌群与微小核糖核酸相互作用的研究进展
Shuhan Dong,Yunpeng Du,Haiyang Wang et al.
Shuhan Dong et al.
Pelvic inflammatory disease (PID) is a common infectious disease of the female upper reproductive tract, and its pathological basis is immune inflammatory response. The imbalance of gut microflora (GM) may lead to the development of inflamm...
Salman M Toor,Eman K Aldous,Aijaz Parray et al.
Salman M Toor et al.
Background: Stroke refers to an abrupt neurological deficit, caused by an acute focal injury of the central nervous system via infarction or hemorrhage due to impaired vascularity, and remains among the leading causes of ...
Long non-coding RNA transcripts in Mycobacterium tuberculosis-host interactions [0.03%]
结核分枝杆菌-宿主相互作用中的长链非编码RNA分子
Mahalakshmi Vijayaraghavan,Shrikanth S Gadad,Subramanian Dhandayuthapani
Mahalakshmi Vijayaraghavan
Tuberculosis (TB) persists as a significant health threat, affecting millions of people all over the world. Despite years of control measures, the elimination of TB has become a difficult task as morbidity and mortality rates remain unaffec...