A comparative analysis of three different methods for the estimation of the basic reproduction number of dengue [0.03%]
三种登革热基本再生数估计方法的比较分析
Rosangela Peregrina Sanches,Eduardo Massad
Rosangela Peregrina Sanches
The basic reproduction number, R0, is defined as the expected number of secondary cases of a disease produced by a single infection in a completely susceptible population, and can be estimated in several ways. For example, from the stabilit...
Fred Brauer,Carlos Castillo-Chavez,Anuj Mubayi et al.
Fred Brauer et al.
Vector-transmitted diseases such as dengue fever and chikungunya have been spreading rapidly in many parts of the world. The Zika virus has been known since 1947 and invaded South America in 2013. It can be transmitted not only by (mosquito...
Controllability and stability analysis of large transcriptomic dynamic systems for host response to influenza infection in human [0.03%]
宿主对流感感染的人体转录动态系统的可控性和稳定性分析
Xiaodian Sun,Fang Hu,Shuang Wu et al.
Xiaodian Sun et al.
Background: Gene regulatory networks are complex dynamic systems and the reverse-engineering of such networks from high-dimensional time course transcriptomic data have attracted researchers from various fields. It is als...
Emergence and spread of drug resistant influenza: A two-population game theoretical model [0.03%]
抗药性流感的产生和传播：一个双人口博弈理论模型
Kamal Jnawali,Bryce Morsky,Keith Poore et al.
Kamal Jnawali et al.
Background: The potential for emergence of antiviral drug resistance during influenza pandemics has raised great concern for public health. Widespread use of antiviral drugs is a significant factor in producing resistant ...
Correlation-based iterative clustering methods for time course data: The identification of temporal gene response modules for influenza infection in humans [0.03%]
基于相关性的迭代聚类方法在时间序列数据分析中的应用：寻找人类对流感感染的基因动态响应模块
Michelle Carey,Shuang Wu,Guojun Gan et al.
Michelle Carey et al.
Many pragmatic clustering methods have been developed to group data vectors or objects into clusters so that the objects in one cluster are very similar and objects in different clusters are distinct based on some similarity measure. The av...
Marc Beauparlant,Robert Smith
Marc Beauparlant
The spread of methicillin-resistant strains of Staphylococcus aureus (MRSA) in health-care settings has become increasingly difficult to control and has since been able to spread in the general community. The prevalence of MRSA within the g...
A mathematical modeling study of the HIV epidemics at two rural townships in the Liangshan Prefecture of the Sichuan Province of China [0.03%]
中国四川省凉山州两个农村镇的HIV流行数学模型研究
Zhimin Su,Caiting Dong,Ping Li et al.
Zhimin Su et al.
Background: As a response to a severe HIV epidemic in the Liangshan Prefecture, one of the worst in China, population based HIV interventions, including two population-wide HIV screening, have been carried out since 2005 ...
Cora L Bernard,Margaret L Brandeau
Cora L Bernard
Structural assumptions in infectious disease models, such as the choice of network or compartmental model type or the inclusion of different types of heterogeneity across individuals, might affect model predictions as much as or more than t...
COVID-19 dynamic modeling of immune variability and multistage vaccination strategies: A case study in Malaysia [0.03%]
马来西亚新冠肺炎免疫差异与多阶段疫苗接种策略的动态模型研究
Hybrid-immune and immunodeficient individuals have been identified by the World Health Organization as two vulnerable groups in the context of COVID-19, but their distinct characteristics remain underexplored. To address this gap, we develo...