Immunotherapy with ex vivo-expanded donor-derived NK cells after haploidentical HSCT in pediatric patients with AML: a phase I pilot study [0.03%]
异体外周血NK细胞回输防治儿童allo-HSCT后复发和移植物抗宿主病的临床研究——Ⅰ期试验结果
Tahereh Rostami,Mohammad Ahmadvand,Bahram Chahardoli et al.
Tahereh Rostami et al.
Background: Post-transplant relapse remains a considerable challenge for achieving successful outcomes in pediatric patients with acute myeloid leukemia (AML) receiving haploidentical hematopoietic stem cell transplantati...
Expert consensus on the management of cytomegalovirus infection in pediatric allogeneic hematopoietic stem cell transplantation [0.03%]
儿童allo-HSCT后巨细胞病毒感染管理中国专家共识
Simone Cesaro,Manuela Spadea,Franca Fagioli et al.
Simone Cesaro et al.
Cytomegalovirus (CMV) infection is the most frequent viral complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). In the pediatric setting, several issues on its management are still debated due to the limited ev...
Could adherence to SAMPL Guidelines improve statistical reporting in clinical manuscripts? Insights from 150 editorial reviews for specialty journals [0.03%]
遵循SAMPL准则能否改善临床论文中的统计报告？来自专业期刊150篇手稿审稿的启示
Michal Ordak
Michal Ordak
Background: Although statistical reporting guidelines such as SAMPL (Statistical Analyses and Methods in the Published Literature) exist, statistical errors remain common in biomedical manuscripts. This study investigates...
Bone marrow vacuolization to curative strategies: Evolving paradigms in VEXAS syndrome management [0.03%]
骨髓空泡化到治愈策略：VEXAS综合征管理的演变范式
Mahmoud I Elbadry,Mohamed Mabed
Mahmoud I Elbadry
VEXAS syndrome (vacuoles, E1 enzyme, X-linked alongside autoinflammatory and somatic) is a severe aggressive inflammation disorder arising in adults that results from acquired changes to the UBA1 gene. These genetic alterations lead to wide...
CRISPR-Cas9: a prominent genome editing tool in the management of inherited blood disorders and hematological malignancies [0.03%]
CRISPR-Cas9技术在遗传性血液病和血液系统恶性肿瘤管理中的基因编辑工具作用不容小觑
Ghazaleh Behrouzian Fard,Mohammad Hossein Ahmadi,Mehran Gholamin et al.
Ghazaleh Behrouzian Fard et al.
Several hematologic diseases with genetic defects, like sickle cell disease and β-thalassemia can be treated with allogeneic hematopoietic stem cell transplantation (HSCT) from healthy donors. However, suitable tissue-matched donors are of...
Effect of adipose-derived mesenchymal stromal/stem cells on mouse mammary tumour growth and formation of lung metastases [0.03%]
脂肪来源的间充质基质/干细胞对小鼠乳腺肿瘤生长和肺转移形成的影响
Kimberly T Peta,Chrisna Durandt,Marlene B van Heerden et al.
Kimberly T Peta et al.
Background: The role of mesenchymal stromal/stem cells (MSCs) in tumour development and progression remains a subject of debate. Previous studies have reported contradictory outcomes, possibly due to variations in experim...
Adolescent and young adult patients with 'Philadelphia negative' myeloproliferative neoplasms: a real world, UK tertiary-centre study [0.03%]
英国三级医疗中心的“费城阴性”髓系肿瘤青少年及年轻成人患者的真实世界研究
Dipal Mehta,Holly Theaker,Hugo Ferreira et al.
Dipal Mehta et al.
Increasing numbers of adolescent and young adult (AYA) patients are diagnosed with myeloproliferative neoplasms (MPNs). Management strategies are often extrapolated from older MPN cohorts and frequently fail to address specific needs. Throu...
Green solvent-based synthesis of diclofenac diethylamine-loaded PCL nanoparticles for sustained drug delivery [0.03%]
基于绿色溶剂的布洛芬二乙胺载PCL纳米颗粒的合成用于持续药物输送
Soolafa Al Soliman,Zaki Ali Ajji,Antoun Al-Laham
Soolafa Al Soliman
Background: Diclofenac, a non-steroidal anti-inflammatory drug (NSAID), has demonstrated promising antitumor properties; however, its clinical application is limited by systemic toxicity. Encapsulation in biodegradable po...
CC486 as a safe and effective bridge to transplant in MDS-del5q with transfusion-dependent anemia following lenalidomide relapse: A case report [0.03%]
伊沙佐米治疗后复发的需要输血的del(5q)MDS患者的过渡疗法：一例报告研究
G Scorpio,A Francesio,S Piemontese et al.
G Scorpio et al.
The immunobiological functions and therapeutic applications of interleukin-17 family in cancer [0.03%]
细胞因子IL-17家族在肿瘤中的免疫生物学功能及治疗应用研究进展
Nasrin Mansuri,Asma&#x;a H Mohamed,Marya Ahsan et al.
Nasrin Mansuri et al.
Interleukin-17 (IL-17) family cytokines play a pivotal role in immune responses and inflammatory processes, significantly impacting various physiological and pathological conditions. This review explores the immunobiological functions of IL...