Comparison of genomic response among patients receiving dendritic cell vaccines pulsed with two different cancer-associated antigens: A retrospective observational study [0.03%]
两种不同癌症相关抗原脉冲树突细胞疫苗接种患者的基因组反应比较：回顾性观察研究
Khin Zay Yar Myint,Masamori Shimabuku,Yoko Shimizu et al.
Khin Zay Yar Myint et al.
Background: The evaluative and prognostic value of liquid biopsy in dendritic cell immunotherapy has not yet been studied, especially with respect to the use of the Wilms tumor gene 1 (WT1) peptide and tumor-specific anti...
A survey on artificial intelligence use for myeloma and lymphoma management [0.03%]
关于人工智能在多发性骨髓瘤和淋巴瘤管理中应用的调查研究
Halima Mokeddem,Layth Sliman,Hachemi Nabil Dellys et al.
Halima Mokeddem et al.
Background: Hematological malignancies, particularly multiple myeloma (MM) and lymphomas, pose major clinical challenges due to their biological complexity and inter-patient heterogeneity. Although diagnostic and therapeu...
Efficacy of bispecific T-cell engagers after CAR T-cell therapy failure in aggressive large B-cell lymphoma [0.03%]
CAR-T细胞治疗失败后用于侵袭性大B细胞淋巴瘤的双特异性T细胞接合器的效果
Mohamed A Kharfan-Dabaja,Tea Reljic,Sarah Abdel-Razeq et al.
Mohamed A Kharfan-Dabaja et al.
No recognized standard of care exists at the present time for treatment for large B-cell non-Hodgkin lymphoma that relapses or progresses after chimeric antigen receptor T-cell (CAR T-cell) therapy. Bispecific T-cell engagers (BiTEs) have e...
Donor demographics and leukopak consistency: Yield and composition as operational benchmarks for cell-therapy starting materials [0.03%]
捐赠者的人口统计学特征与白细胞浓缩液的稳定性：作为细胞治疗起始材料的收得率和成分的运营基准
Irene Gómez-Gràcia,Daniel Gonnermann,Lisa Paschold et al.
Irene Gómez-Gràcia et al.
Introduction: The success of allogeneic cell therapies depends on high-quality starting material derived from healthy donors. However, variability in donor characteristics and collection procedures such as leukapheresis c...
A fault tree analysis of early treatment failure in Acute myeloid leukemia [0.03%]
急性髓系白血病早期治疗失败的故障树分析
Mobina Shrestha,Salina Dahal,Vishal Mandal
Mobina Shrestha
Risk assessment in AML is mainly based on cytogenetic and molecular classification. Even with these systems, induction failure and early death remain common, especially in older patients. In clinical practice, patients often do poorly when ...
Nanogels as innovative drug carriers for RNA-based skin cancer therapy: mechanistic insights and RNA encapsulation [0.03%]
纳米凝胶作为基于RNA的皮肤癌治疗的创新药物载体：机制见解和RNA封装
Nehmat Ghaboura,Muhammad Afzal,Fahad A Al-Abbasi et al.
Nehmat Ghaboura et al.
This review examines the potential application of nanogels as novel drug carriers for RNA-based therapy in the treatment of skin cancer. Relevant information was obtained from reputable scientific databases, including peer-reviewed articles...
Generalized skeletal sclerosis as a potential late effect of total body irradiation after allogeneic hematopoietic stem cell transplantation: A case report [0.03%]
全身照射后异基因造血干细胞移植的远期效应——报告一例 generalized skeletal sclerosis 病例
Bakoubassé Aïssata Son,Lucie Lemeunier,Yazid Belkacemi et al.
Bakoubassé Aïssata Son et al.
High bone mineral density (BMD) is common and sometimes an incidental finding. The causes are numerous. Among them, none has previously been attributed to total body irradiation (TBI). We present the case of a 56-year-old female patient wit...
Impact of the rest period between sequential chemotherapy and conditioning regimen prior to allogeneic hematopoietic stem cell transplantation for high-risk myeloid malignancies [0.03%]
序贯化疗与清淋前的间歇期对高危髓系肿瘤异基因造血干细胞移植后结局的影响
Valentin Amenta,Anne Sonet,Elodie Collinge et al.
Valentin Amenta et al.
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the only curative treatment for relapsed/refractory acute myeloid leukemia (r/rAML), high-risk myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPN). S...
Role of IGF2BP3 as a prognostic biomarker in chronic myeloid leukemia progression and disease stratification [0.03%]
IGF2BP3作为慢性髓系白血病进展和疾病分层的预后生物标志物的作用
Pragati Chauhan,Saba Ubaid,Mohammad Kashif et al.
Pragati Chauhan et al.
Background: Chronic Myeloid Leukemia (CML) progresses through chronic, accelerated, and blast crisis phases, posing challenges for disease stratification and predicting therapeutic response. IGF2BP3 (Insulin-like Growth F...
Oral CXCR4 inhibition with mavorixafor: Emerging therapeutic applications in WHIM syndrome, chronic neutropenia, oncology, and stem cell mobilization [0.03%]
口服CXCR4抑制剂马伏瑞沙芬在WHIM综合征、慢性中性粒细胞减少症、肿瘤学和造血干细胞动员中的新疗法及应用前景
Loi Huynh,Chi Huu Nguyen
Loi Huynh
The CXCR4/CXCL12 signaling axis plays a central role in regulating immune cell trafficking, hematopoietic homeostasis, and organogenesis. However, dysregulation of this axis contributes to the pathogenesis of numerous disorders, highlightin...