Sustained remission in relapsed/refractory diffuse large B cell lymphoma following Glofitamab discontinuation due to JC virus reactivation: balancing efficacy and infectious risk [0.03%]
因重新激活JC病毒而停用Glofitamab后的复发/难治性弥漫大B细胞淋巴瘤持续缓解:疗效与感染风险的平衡
Massimiliano Marinoni,Lucrezia De Marchi,Federico Meconi et al.
Massimiliano Marinoni et al.
The therapeutic landscape for relapsed/refractory diffuse large b-cell lymphoma (R/R DLBCL) is expanding, with bispecific antibodies emerging as key treatment strategies. These drugs have demonstrated high efficacy in this setting of patien...
Chimerism in blood after allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia: Results from a cohort study [0.03%]
异基因造血干细胞移植后急性髓系白血病患者的嵌合体分布特征:队列研究结果
Farah Khemir,Anaïs R Briant,Anne-Claire Gac et al.
Farah Khemir et al.
Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is still a curative option in acute myeloid leukemia treatment (AML) owing to a long-lasting graft-versus-leukemia effect. Relapse remains its major ca...
IDH1 mutation in acute lymphoblastic leukemia-A rare but significant finding [0.03%]
急性淋巴细胞白血病中IDH1突变的少见而重要的发现
Elisa Buzzatti,Luca Guarnera,Giovangiacinto Paterno et al.
Elisa Buzzatti et al.
Digital pathology and artificial intelligence in the era of modern slides: A state of the art [0.03%]
现代病理切片时代的数字病理与人工智能:现状分析
Sawsan Ismail,Firas Shammas,Yamam Makhlof et al.
Sawsan Ismail et al.
Ikram Salih,Meryem Fakhkhari,Hicham Berrougui et al.
Ikram Salih et al.
CAR-T cell therapy marks a groundbreaking advancement in the treatment of hematological malignancies, demonstrating significant potential to induce durable remissions. However, several limitations hinder its effectiveness, including antigen...
Revolutionizing pediatric gene and cell therapy: The hope for lipid-based nanoparticles in blood disorders [0.03%]
儿科基因和细胞疗法的革新:脂质纳米颗粒在血液病治疗中的希望
Fatemeh Zahedipour,Tahereh Mohammadian Gol,Silas Wisser et al.
Fatemeh Zahedipour et al.
The rapidly advancing field of lipid-based nanoparticles (LNPs) as delivery systems for nucleic acids has the potential to revolutionize treatment strategies. LNPs have demonstrated exceptional versatility in delivering genetic material and...
Successful treatment of congenital sideroblastic anemia with low-dose decitabine in a patient with NDUFB11 gene mutation (c.276_278del): A case report [0.03%]
低剂量地西他滨成功治疗NDUFB11基因突变(c.276_278del)所致先天性 sideroblastic贫血1例报告
Juan Wang,Heng Li,Nan Lv et al.
Juan Wang et al.
Background: Congenital sideroblastic anemias (CSAs) are an inherited group of blood disorders due to defects of mitochondrial proteins. The NDUFB11 gene is essential for the assembly of mitochondrial complex Ⅰ protein. M...
AI-assisted statistical review of 100 oncology research articles: compliance with SAMPL guidelines [0.03%]
基于人工智能的100篇肿瘤学研究论文统计审稿:符合SAMPL指南的情况
Michal Ordak
Michal Ordak
Background: Ensuring accurate statistical reporting is critical in oncology research, where data-driven conclusions impact clinical decision-making. Despite standardized guidelines such as the Statistical Analyses and Met...
Optimized GMP-grade Wharton's jelly's mesenchymal stromal cells manufacturing and administration protocol for Graft versus Host disease prevention [0.03%]
优化的GMP级惠登氏胶原基间充质基质细胞制造和给药方案以预防移植物抗宿主病
Cécile Pochon,Romain Perouf,Anne-Béatrice Notarantonio et al.
Cécile Pochon et al.
Background: Wharton's jelly mesenchymal stromal cells (WJ-MSCs) are multipotent cells derived from the umbilical cord with immunomodulatory properties, making them a promising candidate for cell-based therapies targeting ...
Explainable AI for Parkinson's disease prediction: A machine learning approach with interpretable models [0.03%]
用于帕金森病预测的解释性人工智能:一种具有可解释性的模型的机器学习方法
Adebimpe O Esan,David B Olawade,Afeez A Soladoye et al.
Adebimpe O Esan et al.
Background: Parkinson's Disease (PD) is a chronic, progressive neurological disorder with significant clinical and economic impacts globally. Early and accurate prediction remains challenging with traditional diagnostic m...