18F-FDG labelling of hematopoietic stem cells: Dynamic study of bone marrow homing by PET-CT imaging and impact on cell functionality [0.03%]
18F-FDG标记的造血干细胞：正电子发射体层摄影/计算机断层成像研究骨髓归巢的动态过程及其对细胞功能的影响
L Faivre,M Chaussard,L Vercellino et al.
L Faivre et al.
Purpose of the study: After transplantation, cord blood (CB) hematopoietic stem and progenitor cells (HSPCs) are able to home to the bone marrow niche and to reconstitute the hematopoietic system. PET-CT imaging may be a ...
Y Zaid,N Senhaji,Y Darif et al.
Y Zaid et al.
Platelet activation is a complex balance of positive and negative signaling pathways. Several protein kinase C (PKC) isoforms are expressed in human platelets. They are a major regulator of platelet granule secretion, activation and aggrega...
Major bleeding complications in patients treated with direct oral anticoagulants: One-year observational study in a Paris Hospital [0.03%]
口服直接抗凝血药物治疗患者的严重出血并发症：巴黎一家医院的为期一年的观察研究
L Deville,M Konan,A Hij et al.
L Deville et al.
Direct oral anticoagulants (DAOC) are indicated for the treatment of venous thromboembolism and the prevention of stroke or systemic embolism in patients with non-valvular atrial fibrillation. Given their advantages and friendly use for pat...
Down-regulation of tumor suppressor PDCD4 expression in endometrium of adenomyosis patients [0.03%]
腺肌症患者子宫内膜肿瘤抑制因子PDCD4表达下调
Y Liu,X Tan,Z Wang et al.
Y Liu et al.
Objective: Adenomyosis is a common benign gynecological disease which has some malignant behaviors. Programmed cell death 4 (PDCD4) is a newly identified tumor suppressor gene which lowly expresses in various cancers. How...
F Morinet,J Larghero
F Morinet
Mesenchymal stem cells for treating autoimmune diseases: The Chinese experience from lab to clinics [0.03%]
间充质干细胞治疗自身免疫病的中国经验：从实验室到临床
J Liang,D Wang,F Dominique et al.
J Liang et al.
Autoimmune diseases are a group of chronic inflammatory conditions diseases characterized by aberrant activation of the immune system involving either cells or antibodies directed against normal tissues. The current conventional strategies,...
Resetting the immune response after autologous hematopoietic stem cell transplantation for autoimmune diseases [0.03%]
自身免疫性疾病自体造血干细胞移植后重置免疫反应
L C M Arruda,E Clave,H Moins-Teisserenc et al.
L C M Arruda et al.
Autologous hematopoietic stem cell transplantation (AHSCT) is currently investigated as treatment for severe and refractory autoimmune diseases, such as multiple sclerosis (MS), systemic sclerosis (SSc), Crohn's disease (CD) and systemic lu...
P Menasché,V Vanneaux
P Menasché
Stem cell-based therapy is currently tested in several trials of chronic heart failure. The main question is to determine how its implementation could be extended to standard clinical practice. To answer this question, it is helpful to capi...
J De Vos,J Bouckenheimer,C Sansac et al.
J De Vos et al.
This year (2016) will mark the 10th anniversary of the discovery of induced pluripotent stem cells (iPSCs). The finding that the transient expression of four transcription factors can radically remodel the epigenome, transcriptome and metab...
Bone regeneration strategies with bone marrow stromal cells in orthopaedic surgery [0.03%]
骨髓stromal细胞在骨科手术骨再生中的作用策略分析
J Stanovici,L-R Le Nail,M A Brennan et al.
J Stanovici et al.
Bone is the most transplanted tissue human with 1 million procedures every year in Europe. Surgical interventions for bone repair are required for varied reasons such as trauma resulting non-union fractures, or diseases including osteoporos...