Chimeric antigen-receptor T-cell therapy for hematological malignancies and solid tumors: Clinical data to date, current limitations and perspectives [0.03%]
嵌合抗原受体T细胞治疗血液系统恶性肿瘤和实体瘤：临床数据、当前限制及未来展望
J Gauthier,I Yakoub-Agha
J Gauthier
Progress in our understanding of basic immunology along with the advent of bioengineering technologies have made possible the production of human T-cells expressing Chimeric Antigen Receptors (CAR T-cells). These CAR T-cells are designed to...
Association analysis of genetic variants with metabolic syndrome components in the Moroccan population [0.03%]
摩洛哥人群代谢综合征组分的基因变异关联分析
F Lakbakbi El Yaagoubi,H Charoute,I Morjane et al.
F Lakbakbi El Yaagoubi et al.
This study aimed to analyze the association between UBE2E2, G6PC2, PROX1, DUSP9, ADCY5 and APOC3 polymorphisms and the risk of metabolic syndrome (MetS) in Moroccan patients. The study was applied on 316 unrelated individuals from Morocco, ...
Bio-scaffolds in organ-regeneration: Clinical potential and current challenges [0.03%]
器官再生中生物支架的临床潜力及当前挑战
S Yesmin,M B Paget,H E Murray et al.
S Yesmin et al.
Cadaveric organ transplantation represents the definitive treatment option for end-stage disease but is restricted by the shortage of clinically-viable donor organs. This limitation has, in part, driven current research efforts for in vitro...
Long-term follow up of invasive aspergillosis in allogeneic stem cell transplantation recipients and leukemia patients: Differences in risk factors and outcomes [0.03%]
allo-HSCT受体和白血病患者侵袭性曲霉病的长期预后及其危险因素和影响因素的区别
S Bonnet,R Duléry,K Regany et al.
S Bonnet et al.
Antifungal prophylaxis (AP) has dramatically changed the epidemiology of invasive aspergillosis (IA). To better understand the differences in terms of clinical significance of IA between allogeneic stem cell transplantation (allo-SCT) recip...
How to prevent relapse after allogeneic hematopoietic stem cell transplantation in patients with acute leukemia and myelodysplastic syndrome [0.03%]
allo-HSCT后急性白血病和骨髓增生异常综合征患者复发的预防措施
N Yafour,F Beckerich,C E Bulabois et al.
N Yafour et al.
Disease relapse remains the first cause of mortality of hematological malignancies after allogeneic hematopoietic stem cell transplantation (allo-HCT). The risk of recurrence is elevated in acute myeloid leukemia (AML) patients with high-ri...
Prognostic significance of preoperative albumin-to-globulin ratio in patients with cholangiocarcinoma [0.03%]
术前血清白蛋白/球蛋白比值与胆管癌患者预后的关系
Q Lin,Z-H Lin,J Chen et al.
Q Lin et al.
Background: This study aimed to assess the prognostic value of the serum albumin to globulin ratio (AGR) in cholangiocarcinoma patients after surgery. Met...
Immunohistochemical and genetic exploration of incompatible A blood group antigen expression in invasive micropapillary breast carcinoma: A case report [0.03%]
侵袭性微乳头状乳腺癌中不相容A血型抗原表达的免疫组化和基因探索：病例报告
S Zouine,Z Orfi,K Kojok et al.
S Zouine et al.
Introduction: Invasive Micropapillary Carcinoma (IMPC) of the breast is a relatively rare subtype of invasive ductal carcinoma and represents the most inherently aggressive form. Expression of incompatible blood group A a...
I Ghariani,N Braham,S Hamzaoui et al.
I Ghariani et al.
Platelet satellitism is a rare phenomenon observed in blood smears obtained from blood anticoagulated with EDTA with an estimated frequency at 0.008%. It is characterized by platelet rosetting around neutrophils and in rare cases around oth...
A Gugliandolo,P Bramanti,E Mazzon
A Gugliandolo
Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, and as a consequence, by decreased dopamine levels in the striatum. Currently available therapies are not able to...