Effect and safety of recombinant human thrombopoietin on haematopoietic reconstitution after allogeneic haematopoietic cell transplantation [0.03%]
rhTPO对异基因造血细胞移植后造血重建的效果及安全性研究
Meilin Tian,Le Ma,Jieping Chen et al.
Meilin Tian et al.
Delayed platelet engraftment (DPE) and thrombocytopenia are common complications following myeloablative conditioning in the advanced stage of allogeneic haematopoietic cell transplantation (allo-HCT), and they are associated with transplan...
Effect of AML-exosomes on the cellular and molecular properties of bone marrow mesenchymal stromal cells: Expression of JAK/STAT signaling genes [0.03%]
急性髓系白血病外泌体对骨髓间充质干细胞的细胞和分子特性的影响：JAK/STAT信号通路基因表达
Maryam Nabigol,Laya Khodayi Hajipirloo,Bentolhoda Kuhestani-Dehaghi et al.
Maryam Nabigol et al.
Purpose of study: Despite the various therapeutic options introduced for AML treatment, therapy resistance and relapse are still the main obstacles. It is well known that alterations in the bone marrow microenvironment (B...
The transplantation effect of pegylated granulocyte colony-stimulating factor mobilized hematopoietic stem cells may be superior to that of G-CSF mobilized hematopoietic stem cells in haploidentical allogeneic hematopoietic cell transplantation [0.03%]
异基因造血干细胞移植时，与G-CSF动员的造血干细胞相比，PEG-rhG-CSF动员的造血干细胞移植效果更佳：一项非劣性研究
Junjie Cao,Xianxu Zhuang,Renzhi Pei et al.
Junjie Cao et al.
Granulocyte colony-stimulating factor (G-CSF) mobilized peripheral blood stem cells have become the preferred source of hematopoietic stem cells. We compared the effectiveness of G-CSF and pegylated G-CSF (peg-G-CSF) for hematopoietic stem ...
Point of care CD19 chimeric antigen receptor (CAR) T-cells for relapsed/refractory acute myeloid leukemia (AML) with aberrant CD19 antigen expression [0.03%]
用于治疗CD19异常表达的复发/难治性急性髓系白血病的护理点CD19嵌合抗原受体（CAR）T细胞疗法
Ivetta Danylesko,Noga Shem-Tov,Ronit Yerushalmi et al.
Ivetta Danylesko et al.
Relapsed/refractory (r/r) acute myeloid leukemia (AML) is associated with poor prognosis. CD19 is a B-cell marker, is aberrantly expressed in AML, mostly with t(8; 21)(q22; q22.1). Here we report the results of a phase 2 study giving point ...
Selective red blood cell depletion by apheresis in sheep causes severe normovolemic anemia [0.03%]
绵羊选择性红细胞去除术导致重度等容性贫血
Anna-Lena Semmler,Jan-Philipp Köhler,Lara Regolien et al.
Anna-Lena Semmler et al.
Background: The setting of normovolemic anemia is required for a variety of research applications, such as testing of novel medication for anemia treatment. Unfortunately, large animal models using full blood draw and rep...
Impaired survival of patients with non donor-specific anti-HLA antibodies before HLA-mismatched allogeneic stem cell transplantation [0.03%]
mismatchedallo-HSCT前非供者特异性抗HLA抗体阳性患者预后较差
Antonio Milano,Giuliana Lando,Giulia Di Maggio et al.
Antonio Milano et al.
Background: While the detrimental role of donor-specific anti-HLA antibodies (DSAs) is well-described in the setting of hematopoietic stem cell transplantation (HSCT), few studies focus on non donor-specific ones and with...
Feasibility of co-transplantation of umbilical cord blood and third-party mesenchymal stromal cells after (non)myeloablative conditioning in patients with hematological malignancies [0.03%]
非清髓或减低剂量清髓预处理后联合应用脐血和第三方间充质基质细胞移植治疗血液系统恶性肿瘤的可行性研究
Simon Planken,Ann De Becker,Tessa Kerre et al.
Simon Planken et al.
Umbilical cord blood (UCB) is an alternative source of stem cells for patients lacking a 9/10 or 10/10 HLA identical donor. However, after UCB transplantation, time to engraftment and immune recovery are prolonged, increasing the risk of fa...
Clinical image: A new category of articles in current research in translational medicine [0.03%]
临床医学影像：转化医学研究新文种
Tamim Alsuliman
Tamim Alsuliman
Genetic variants of dectin-1 and their antifungal immunity impact in hematologic malignancies: A comprehensive systematic review [0.03%]
Dectin-1基因变异及其在血液系统恶性肿瘤的抗真菌免疫作用的影响：一项全面的系统综述
Mojtaba Aghaei,Reyhane Khademi,Mohammad Ali Jalali Far et al.
Mojtaba Aghaei et al.
Background: Fungal infections pose a significant threat to individuals with hematologic malignancies due to compromised immune systems. Dectin-1, a pivotal pattern recognition receptor, plays a central role in antifungal ...
Pitfalls in definitions on respiratory viruses and particularities of Adenovirus infection in hematopoietic cell transplantation patients: Recommendations from the EBMT practice harmonization and guidelines committee [0.03%]
造血干细胞移植患者呼吸道病毒定义的陷阱及腺病毒感染的特点：EBMT实践规范化与指南委员会的建议
José Luis Piñana,Simone Cesaro,Malgorzata Mikulska et al.
José Luis Piñana et al.
In 2023, the EBMT Practice harmonization and Guidelines Committee partnered with the EBMT Infection Diseases Working Party (IDWP) to undertake the task of delivering best practice recommendations, aiming to harmonize by expert consensus, th...