Cardiac TRPM7 Causes Diabetic Heart Failure With Preserved Ejection Fraction [0.03%]
心脏TRPM7导致射血分数保留的心力衰竭糖尿病并发症
Man Liu,Hong Liu,Gyeoung-Jin Kang et al.
Man Liu et al.
Hypomagnesemia (HypoMg) and subsequent oxidative stress cause diabetic cardiac diastolic dysfunction and heart failure with preserved ejection fraction. A Mg2+ transporter with channel and kinase function, transient receptor potential catio...
Cigarette Tar Enhanced ECs Pyroptosis via CAMKII/Drp1/mtDNA: Novel Insight Into the Mechanism of Plaque Erosion [0.03%]
尼古丁促进EC线粒体依赖性细胞焦亡的机制及对动脉粥样硬化斑块稳定性的影响研究
Xing Luo,Ji Li,Yuwu Chen et al.
Xing Luo et al.
Smoking is the only cardiovascular risk factor for plaque erosion. We found cigarette tar resulted in erosion-like lesion development in apolipoprotein E-/- mice, with mural thrombosis, discontinuous endothelium, platelet activation, smooth...
Matthias Nahrendorf
Matthias Nahrendorf
Increased Generation of Hypoxanthine: How Adaptation of Purine Metabolism Drives Vascular Remodeling in Pulmonary Hypertension [0.03%]
次黄嘌呤生成增加：嘌呤代谢适应驱动肺动脉高压血管重塑的机制
Katrin Schäfer
Katrin Schäfer
Adipose Tissue Stress-Related Changes in Mice and Humans with HFpEF [0.03%]
HFpEF小鼠和人类受试者的脂肪组织应激相关变化
Lisandro Maya-Ramos,Philipp E Scherer
Lisandro Maya-Ramos
Jeffrey E Saffitz
Jeffrey E Saffitz
Evaluation of Tideglusib as a Disease Modifying Therapy in Murine Models of Arrhythmogenic Cardiomyopathy [0.03%]
评估 Tideglusib 在小鼠致心律失常性心肌病模型中的疾病修饰疗法效果
Nipun Malhotra,Omer Cavus,Michael J Wallace et al.
Nipun Malhotra et al.
Arrhythmogenic cardiomyopathy (ACM) is an inherited heart disease, and current pharmacological therapies are directed toward the management of electrical manifestations. To date, none address the underlying pathophysiology of this progressi...
Unleashing the Power of the Beehive to Begin a New Era for JACC: Basic to Translational Science [0.03%]
释放蜂巢的力量，开启JACC基础到转化科学新时代
Matthias Nahrendorf
Matthias Nahrendorf
Mitophagy Regulators as Novel Targets in Sepsis-Induced Myocardial Dysfunction [0.03%]
线粒体自噬调节因子在脓毒症诱导的心肌功能障碍中的作用
Katharina Friedrich,Kai Kappert
Katharina Friedrich
Exploring Mechanisms of Pulmonary Artery Banding in a Rat Model of Dilated Cardiomyopathy [0.03%]
探索肺动脉束带法治疗扩张型心肌病大鼠模型的作用机制
Yi Ye,Veli K Topkara
Yi Ye