Inflammatory Fibroblasts Ready for Their Close-up: Characterization and Impact on CVB3-Induced Myocarditis [0.03%]
炎症性成纤维细胞特写:CVB3诱导的心肌炎中的表征和影响
Anna Rizakou
Anna Rizakou
[Figure: see text] Keywords: IL-1; inflammatory fibroblasts; plasticity; viral myocarditis.
Nanoparticle-Enabled Plasma Proteomics of Experimental Atherosclerosis in Mice [0.03%]
纳米颗粒增强的小鼠实验性动脉粥样硬化血浆蛋白质组学研究
Constance Delwarde,Joan T Matamalas,Sarvesh Chelvanambi et al.
Constance Delwarde et al.
Dyslipidemia, marked by elevated low-density lipoprotein cholesterol, is a major risk factor for coronary heart disease. Mouse experimental systems, such as Ldlr-/- mice that develop atherosclerosis and metabolic disorders when fed a high-f...
Decoding Plaque Instability Through Plasma Proteomics Profiling? [0.03%]
通过血浆蛋白质组学谱分析解读动脉粥样硬化斑块的不稳定性吗?
Bhawana Singh,Manuel Mayr
Bhawana Singh
[Figure: see text] [Figure: see text] Keywords: atherosclerosis; biomarkers; proteomics...
Thorsten Kessler
Thorsten Kessler
[Figure: see text] Keywords: atherosclerosis; plasma; proteomics.
Jason Hong
Jason Hong
[Figure: see text] Keywords: biopsy; endothelial dysfunction; network medicine; precision medicine; pulmonar...
From Genetics to Functional Genomics: Redefining Susceptibility in Takotsubo Syndrome [0.03%]
从遗传学到功能基因组学:应重新定义应激性心肌病的易感性
Liam S Couch
Liam S Couch
[Figure: see text] Keywords: Takotsubo syndrome; genetics; genomics; suspectibility.
CXCL12 in Cardiac Remodeling: Defining Extracellular Matrix Interactions as a Novel Signaling Repertoire [0.03%]
Cxcl12在心脏重塑中的作用:定义细胞外基质相互作用作为新的信号谱系
Alan J Mouton
Alan J Mouton
[Figure: see text] Keywords: angiogenesis; chemokines; extracellular matrix; fibroblasts; myocardial infarct...
Impaired Cardiac Myosin Super-Relaxation as an Energy-Dissipating Process in Human Heart Failure with Reduced Ejection Fraction [0.03%]
射血分数降低型心力衰竭中心肌肌球蛋白超松弛的耗能作用机制受损
Weikang Ma,Chahida Chaami,Elise Gerlach Melhedegaard et al.
Weikang Ma et al.
Systolic heart failure is increasingly recognized as a disease of impaired cardiac energy metabolism. Here, the authors show that cardiac myosin super-relaxation (an energy-conserving myosin state) is destabilized in failing human myocardiu...
Myosin Super-Relaxation in Human Heart Failure With Reduced Ejection Fraction: A Sarcomeric Role in Energetic Waste [0.03%]
射血分数降低的心力衰竭患者肌球蛋白超松弛化: sarcomere在能量浪费中的作用
Anthony J Baker
Anthony J Baker
[Figure: see text] Keywords: energetics; heart failure; myosin; post-translational modifications.
Individualized Interactomes From Pulmonary Arterial Hypertension Cell Biopsies Inform Pharmacotherapeutic Response [0.03%]
肺动脉高压细胞活检的个体化互作组指导药物治疗反应
Rui-Sheng Wang,Navneet Singh,Henri Wathieu et al.
Rui-Sheng Wang et al.
Pulmonary arterial hypertension (PAH) is characterized by molecular heterogeneity, which has limited personalized approaches to treatment selection. In this study, the authors assembled a novel pipeline that leveraged pulmonary artery endot...