Plasma Proteomic Signatures of Left Atrial Dysfunction and Cerebral Small Vessel Disease: Elucidating Heart-Brain Connections [0.03%]
血浆蛋白质组学标志物与左心房功能不全及脑小血管病的相关性：阐明心脏-大脑关联性
Eugene S J Tan,Ming Ann Sim,Hyungwon Choi et al.
Eugene S J Tan et al.
Reduced left atrial (LA) strain is associated with cerebral small vessel disease (CSVD). In memory clinic patients without atrial fibrillation, LA reservoir strain and LA conduit strain were significantly associated with white matter hyperi...
Macrophage-Specific SPP1 Contributes to Pressure Overload-Induced Cardiac Dysfunction and Maladaptive Remodeling [0.03%]
巨噬细胞特异性SPP1参与压力超负荷诱导的心肌功能障碍和不利重塑
Weijian Ye,Jia Sun,Enzhao Shen et al.
Weijian Ye et al.
Cardiac macrophages display remarkable functional plasticity via heterogeneous subpopulations and a dynamic secretome, orchestrating key regulatory events during pressure overload-induced myocardial remodeling. However, the specific pathoge...
Increased Arrhythmic Risk in Obesity Is Transduced by Adipose Tissue-Derived Extracellular Vesicles [0.03%]
肥胖引起的心律失常风险增加由脂肪组织来源的细胞外囊泡介导
Worawan B Limpitikul,Marta Garcia-Contreras,Paul Spangler et al.
Worawan B Limpitikul et al.
Obesity drives atrial fibrillation and ventricular arrhythmias, yet whether direct fat-heart communication mediates this risk is unknown. The authors demonstrate that human atrial myocytes from obese individuals exhibit prolonged action pot...
Zhilin Qu,Kalyanam Shivkumar
Zhilin Qu
Two principal mechanisms have been proposed to explain impulse propagation in cardiac tissue. The first is low-resistance gap-junctional coupling, which explains many experimental observations but does not fully account for all findings, su...
Matthias Nahrendorf
Matthias Nahrendorf
Simplified and Refined Murine Model of Reversible Aortic Constriction for Characterizing Cardiac Functional Recovery [0.03%]
简化和精炼的小鼠主动脉可逆性缩窄模型用于表征心脏功能恢复特点
Elnaz Ghajar-Rahimi,Pierre Sicard,Ava Flynn et al.
Elnaz Ghajar-Rahimi et al.
James Cranley
James Cranley
Reply: Strengths and Limitations of the Renal Locoregional Perfusion Platform [0.03%]
关于肾脏局部灌注平台的优势和局限性的评论
Maximilian Y Emmert,Johannes Holzmeister,Volkmar Falk et al.
Maximilian Y Emmert et al.
Matthias Nahrendorf
Matthias Nahrendorf
Adipose-Cardiac Crosstalk in Obesity-Related Atrial Fibrillation: The Emerging Role of Extracellular Vesicles [0.03%]
肥胖相关心房颤动的脂肪-心脏相互作用：细胞外囊泡的作用不容忽视
Naveed Akbar,Svetlana Reilly
Naveed Akbar