J David Port
J David Port
Micro-RNA Analysis in Pulmonary Arterial Hypertension: Current Knowledge and Challenges [0.03%]
肺动脉高压中的微小核糖核酸分析：现状与挑战
Cátia A Santos-Ferreira,Mónica T Abreu,Carla I Marques et al.
Cátia A Santos-Ferreira et al.
Pulmonary arterial hypertension (PAH) is a rare, chronic disease of the pulmonary vasculature that is associated with poor outcomes. Its pathogenesis is multifactorial and includes micro-RNA (miRNA) deregulation. The understanding of the ro...
Rejuvenation of Senescent Endothelial Progenitor Cells by Extracellular Vesicles Derived From Mesenchymal Stromal Cells [0.03%]
来源于间充质基质细胞的细胞外囊泡使衰老的内皮祖细胞年轻化
Liyong Wang,Jianqing Wei,Andrea Da Fonseca Ferreira et al.
Liyong Wang et al.
Mesenchymal stromal cell (MSC) transplantation is a form of the stem-cell therapy that has shown beneficial effects for many diseases. The use of stem-cell therapy, including MSC transplantation, however, has limitations such as the tumorig...
Transcatheter-Delivered Expandable Bioresorbable Polymeric Graft With Stenting Capacity Induces Vascular Regeneration [0.03%]
可通过导管递送的具有支架功能的可膨胀生物可降解高分子移植血管能诱发血管再生
Renee Duijvelshoff,Maria S Cabrera,Bart Sanders et al.
Renee Duijvelshoff et al.
As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally in...
SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function: Implications for Diagnostic Marker Development in Pulmonary Arterial Hypertension [0.03%]
SCUBE1调控肺动脉高压中与BMPR2相关的内皮细胞功能：作为诊断标志物的潜在应用价值
Wei Sun,Ying Tang,Yi-Yin Tai et al.
Wei Sun et al.
Utilizing publicly available ribonucleic acid sequencing data, we identified SCUBE1 as a BMPR2-related gene differentially expressed between induced pluripotent stem cell-endothelial cells derived from pulmonary arterial hypertension (PAH) ...
β-Arrestin-Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate [0.03%]
偏向性AT1激动剂TRV027产生持续的正性肌力作用而不增加心率
Toshihide Kashihara,Hiroyuki Kawagishi,Tsutomu Nakada et al.
Toshihide Kashihara et al.
The treatment of pediatric heart failure is a long-standing unmet medical need. Angiotensin II supports mammalian perinatal circulation by activating cardiac L-type Ca2+ channels through angiotensin type 1 receptor (AT1R) and β-arrestin. T...
RNA Vaccines for COVID-19: 5 Things Every Cardiologist Should Know [0.03%]
关于COVID-19的RNA疫苗：每位心脏病专家都需要了解的五件事
Chien-Jung Lin,Robert P Mecham,Douglas L Mann
Chien-Jung Lin
Percutaneous Chordae Mitral Repair: Is it the Right Way to Fix Mitral Regurgitation? [0.03%]
经皮三尖瓣腱索修复术：治疗二尖瓣反流的正确方法吗？
Thomas Modine,Mathieu Pernot,Walid Ben-Ali
Thomas Modine
Neuromodulation of Dorsal Root Ganglia: Chronic Pain Mitigation and Autonomic Implications [0.03%]
外周神经调控：慢性疼痛缓解及自主神经系统影响
Jeffrey L Ardell
Jeffrey L Ardell