Sequential nanocatalytic therapy and lysosomal dysfunction for overcoming castration-resistant prostate cancer [0.03%]
序贯纳米催化治疗与溶酶体功能障碍克服去势抵抗性前列腺癌
Jinming Di,Weijen Lee,Yanteng Xu et al.
Jinming Di et al.
Castration-resistant prostate cancer (CRPC) remains lethal due to adaptive resistance mechanisms such as stress-induced autophagy and NF-κB survival signaling. Here, an injectable fiber-in-hydrogel depot is developed for sequential deliver...
Microalgae extracellular vesicles-loaded dual antioxidative and anti-inflammatory hydrogel system for wound healing and peripheral nerve repair in diabetes [0.03%]
微藻外泌体负载双抗氧化抗炎水凝胶系统促进糖尿病伤口愈合及周围神经修复
Jia Dong,Boya Cheng,Xuening Zhang et al.
Jia Dong et al.
Chronic wound healing and peripheral nerve repair in diabetes remain a major clinical challenge due to persistent oxidative stress, inflammation, and impaired tissue regeneration. Here, we developed a multifunctional hydrogel, mEVs@TAgel, f...
Corrigendum for Figure and author affiliation corrections in previously published articles of Bioactive Materials [0.03%]
Bioactive Materials 图表及作者隶属关系更正说明
[This corrects the article DOI: 10.1016/j.bioactmat.2025.12.057.][This corrects the article DOI: 10.1016/j.bioactmat.2023.09.004.][This corrects the article DOI: 10.1016/j.bioactmat.2026.03.059.]. ...
Published Erratum
Bioactive materials. 2026 May 7:64:255-261. DOI:10.1016/j.bioactmat.2026.05.006 2026
Hit the bull's eye: Engineered extracellular vesicles for targeted therapy [0.03%]
靶向治疗的工程化细胞外囊泡：一箭中的
Yijin Cai,Hengjing Zhang,Xinao Fan et al.
Yijin Cai et al.
Extracellular vesicles (EVs) are nanoscale vesicles secreted by most cell types and have a similar composition to their parent cells. By delivering effector molecules, EVs serve as mediators of intercellular communication and hold significa...
Modeling ventricular tachycardia in genetic long QT syndrome using engineered cardiac tissues [0.03%]
使用心脏组织芯片模拟长QT综合征室性心动过速
Richard Z Zhuang,Georgia Doufexi,Marc Yehya et al.
Richard Z Zhuang et al.
Congenital long QT syndrome (LQTS) predisposes patients to malignant ventricular tachycardias, yet existing in vitro models do not fully capture the clinical arrhythmic phenotypes that determine patient outcomes. We report the development o...
Current and emerging antibacterial strategies for periprosthetic joint infection: An overview [0.03%]
人工关节感染的当前及新兴抗菌策略概述
Marco Fosca,Veronica Manescu,Iulian Antoniac et al.
Marco Fosca et al.
Periprosthetic Joint Infection (PJI) represents one of the most serious complications following joint arthroplasty, with impactful consequences in the clinic and economy. Characterized by biofilm formation on implant surfaces, PJI poses sig...
Mitochondrial micro-nano reactors via enhancing mitochondrial transfer and mitophagy for alleviating metabolic crisis [0.03%]
通过增强线粒体转移和自噬构建线粒体微纳米反应器以缓解代谢危象
Jiayi Mao,Wenzheng Xia,Minxiong Li et al.
Jiayi Mao et al.
Energy metabolic dysfunction is a major cause of impaired chronic wounds healing, in which disrupted mitochondrial transfer and autophagy imbalance further aggravate the cellular energy crisis. In this study, single-cell RNA sequencing (scR...
An albumin-armed fibronectin fragment assembly on stents enables immune evasion, thrombosis prevention, and self-adaptive vascular cell selectivity [0.03%]
一种白蛋白武装的纤连蛋白片段能够在支架上装配，实现免疫逃逸、预防血栓和自我适应血管细胞选择性
Qing Ma,Wenxuan Wang,Xiaohui Mou et al.
Qing Ma et al.
Reconstruction of a healthy endothelium following stent implantation is critical for enhancing vascular healing process. Surface engineering of stents with endothelial cell (EC)-selective molecules represents one of the most effective strat...
Neonatal small extracellular vesicle-loaded GelNB hydrogel reprograms the vascular-immune microenvironment for spinal cord injury repair [0.03%]
新生儿小细胞外囊泡负载的GelNB水凝胶重新编程血管-免疫微环境以修复脊髓损伤
Feifei Yuan,Chaoran Shi,Xisong Liang et al.
Feifei Yuan et al.
Adult mammals with spinal cord injury (SCI) face permanent disability from failed regeneration and scarring, while neonatal mice achieve scarless repair. We show neonatal mouse circulating blood-derived small extracellular vesicles (NCE) re...
"Artificial platelet injection system": a plug-and-play platelet-based lysosome-targeting chimera for targeted protein degradation [0.03%]
“人工血小板注射系统”：一种基于血小板的针对溶酶体靶向嵌合体的即插即用型蛋白质降解系统
Chenming Zou,Haichao Zhu,Yuepeng Tang et al.
Chenming Zou et al.
Targeted protein degradation technology via lysosomal machinery has attracted extensive attention due to its capability of degrading extracellular and membrane-associated proteins. Conventional lysosome-based degraders are established by co...