Use of the Human Coronavirus 2012 (MERS) GeneSig kit for MERS-CoV detection [0.03%]
用于中东呼吸综合征冠状病毒检测的2012年人类冠状病毒(MERS)GeneSig试剂盒
Rouba Hoteit,Dina Shammaa,Rami Mahfouz
Rouba Hoteit
Introduction: Mortality due to MERS-CoV infection is common especially among immunocompromised patients. The pathogenesis and the transmission mode of this virus are still not well understood. The name of the virus is der...
TGFβ and activin A in the tumor microenvironment in colorectal cancer [0.03%]
肿瘤微环境中的TGFβ和活化素A在结直肠癌中的作用
Jasmin Zessner-Spitzenberg,Alexandra L Thomas,Nancy L Krett et al.
Jasmin Zessner-Spitzenberg et al.
Although overall survival in colorectal cancer (CRC) is increasing steadily due to progress in screening, therapeutic options and precise diagnostic tools remain scarce. As the understanding of CRC as a complex and multifactorial condition ...
Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain [0.03%]
血管内皮生长因子受体-1（Flt-1）的阻滞可揭示一种治疗骨关节炎性关节痛的新方法
Vaskar Das,Ranjan Kc,Xin Li et al.
Vaskar Das et al.
Osteoarthritis (OA) is a painful and debilitating disease. A striking feature of OA is the dramatic increase in vascular endothelial growth factor (VEGF) levels and in new blood vessel formation in the joints, both of which correlate with t...
Amino acid 118 in the Deafness Causing (DFNA20/26) ACTG1 gene is a Mutational Hot Spot [0.03%]
导致耳聋的ACTG1基因（DFNA20/26）中的第118位氨基酸是突变热点
Li Wang,Denise Yan,Litao Qin et al.
Li Wang et al.
Background: Hearing loss is an economically and socially important cause of human morbidity, affecting 360 million people (over 5% of the world's population), of whom 32 million are children. Of the estimated minimum of 5...
Bradley J Wagstaff,Linda Wang,Susan Lai et al.
Bradley J Wagstaff et al.
Mobile elements have significantly impacted genome structure of most organisms. The continued activity of the mobile element, LINE-1 (L1), through time has contributed to the accumulation of over half a million L1 copies in the human genome...
Selection of Reference Genes for Studies of Human Retinal Endothelial Cell Gene Expression by Reverse Transcription-Quantitative Real-Time Polymerase Chain Reaction [0.03%]
逆转录定量实时聚合酶链反应研究人视网膜内皮细胞基因表达的参考基因选择
Binoy Appukuttan,Liam M Ashander,Yuefang Ma et al.
Binoy Appukuttan et al.
Background: Human retinal endothelial cells are employed increasingly for investigations of retinal vascular diseases. Analysis of gene expression response to disease-associated stimuli by reverse transcription-quantitati...
Extracellular matrix protein production in human adipose-derived mesenchymal stem cells on three-dimensional polycaprolactone (PCL) scaffolds responds to GDF5 or FGF2 [0.03%]
人源性脂肪来源间充质干细胞在三维聚己内酯(PCL)支架上产生细胞外基质蛋白的反应受到GDF5或FGF2的影响
Yan Su,Janet M Denbeigh,Emily T Camilleri et al.
Yan Su et al.
Purpose: The poor healing potential of intra-articular ligament injuries drives a need for the development of novel, viable 'neo-ligament' alternatives. Ex vivo approaches combining stem cell engineering, 3-dimensional bi...
Arun J Singh,Michael K Gross,Theresa M Filtz et al.
Arun J Singh et al.
Background: Genome-wide mapping reveals chromatin landscapes unique to cell states. Histone marks of regulatory genes involved in cell specification and organ development provide a powerful tool to map regulatory sequence...
Effects of corexit oil dispersants and the WAF of dispersed oil on DNA damage and repair in cultured human bronchial airway cells, BEAS-2B [0.03%]
油分散剂和分散油的水可萃取 fraction 对人支气管上皮细胞 DNA 损伤及修复的影响
Danielle Major,Rebecca S Derbes,He Wang et al.
Danielle Major et al.
Large quantities of dispersants were used as a method to disperse the roughly 210 million gallons of spilled crude oil that consumed the Gulf of Mexico. Little is known if the oil-dispersant and oil-dispersant mixtures on human airway BEAS-...