Sleep disorders among Aboriginal Australians with Machado-Joseph Disease: Quantitative results from a multiple methods study to assess the experience of people living with the disease and their caregivers [0.03%]
澳大利亚马查多-约瑟夫病患者的睡眠障碍：定量研究结果，该研究采用多种方法评估患病人群及其照顾者的经历
Desireé LaGrappe,Libby Massey,Anuk Kruavit et al.
Desireé LaGrappe et al.
Background: Machado-Joseph Disease (MJD), or Spinocerebellar Ataxia Type 3 (SCA3), is a genetic disorder that causes progressive muscle weakness, loss of motor control, ataxia and permanent physical disability. Sleep dist...
Microglia are involved in the protection of memories formed during sleep deprivation [0.03%]
小胶质细胞参与睡眠剥夺期间形成的记忆的保护作用
Nicholas W Gentry,Thomas McMahon,Maya Yamazaki et al.
Nicholas W Gentry et al.
Sleep deprivation can generate inflammatory responses in the central nervous system. In turn, this inflammation increases sleep drive, leading to a rebound in sleep duration. Microglia, the innate immune cells found exclusively in the CNS, ...
A randomized controlled trial on the effect of blue-blocking glasses compared to partial blue-blockers on melatonin profile among nulliparous women in third trimester of the pregnancy [0.03%]
一项关于孕妇晚间使用蓝光过滤眼镜和普通眼镜对体内褪黑素水平影响的随机对照实验研究
Randi Liset,Janne Grønli,Roger Ekeberg Henriksen et al.
Randi Liset et al.
Objective: In pregnancy melatonin regulates circadian rhythms, induce sleep, and has a neuroprotective positive effect on fetal development. Artificial blue light in the evening delays and suppresses melatonin production....
Amount of < 1Hz deep sleep correlates with melatonin dose in military veterans with PTSD [0.03%]
一赫兹以下深度睡眠量与患有创伤后应激障碍的退伍军人褪黑激素剂量相关
Julie Onton,Lu D Le
Julie Onton
Military veterans with posttraumatic stress disorder often complain of non-restful sleep, which further exacerbates their symptoms. Our previous study showed a deficit in Lo Deep sleep, or slow oscillations, in the PTSD population compared ...
Chronic methamphetamine uncovers a circadian rhythm in multiple-unit neural activity in the dorsal striatum which is independent of the suprachiasmatic nucleus [0.03%]
慢性甲基苯丙胺会诱发黑质多巴胺能神经元的昼夜节律性胞外多巴胺浓度变化
Shota Miyazaki,Yu Tahara,Christopher S Colwell et al.
Shota Miyazaki et al.
The dorsal striatum forms part of the basal ganglia circuit that is a major regulator of voluntary motor behavior. Dysfunction in this circuit is a critical factor in the pathology of neurological (Parkinson's and Huntington's disease) as w...
Spatial sensitivity of human circadian response: Melatonin suppression from on-axis and off-axis light exposures [0.03%]
人circadian反应的空间敏感度：轴向和非轴向光源照射造成的褪黑素抑制
Rohan Nagare,Mark S Rea,Mariana G Figueiro
Rohan Nagare
A better understanding of the spatial sensitivity of the human circadian system to photic stimulation can provide practical solutions for optimized circadian light exposures. Two psychophysical experiments, involving 25 adult participants i...
Rapid eye movement (REM) sleep microarchitecture is altered in patients with wake-up ischemic stroke: A polysomnographic study [0.03%]
醒发缺血性卒中患者快速眼动睡眠微结构改变：多导睡眠图监测研究
Jaidaa Mekky,Osama El-Kholy,Eman Hamdy et al.
Jaidaa Mekky et al.
It is well established that certain alteration of sleep disorders occur in patients with wake-up stroke (WUS) such as sleep disordered breathing, periodic limb movements and sleep duration. However, the data are lacking about the microarchi...
A review of the current state of knowledge on sex differences in sleep and circadian phenotypes in rodents [0.03%]
关于啮齿动物睡眠和昼夜节律表型性别差异的现状回顾
Rama Dib,Nicole J Gervais,Valérie Mongrain
Rama Dib
Sleep is a vital part of our lives as it is required to maintain health and optimal cognition. In humans, sex differences are relatively well-established for many sleep phenotypes. However, precise differences in sleep phenotypes between ma...
Effect of a dynamic lighting intervention on circadian rest-activity disturbances in cognitively impaired, older adults living in a nursing home: A proof-of-concept study [0.03%]
一种动态照明干预对护理机构中认知障碍老年人昼夜节律休息活动紊乱影响的概念验证性研究
Lone Baandrup,Poul J Jennum
Lone Baandrup
Development of non-pharmacological interventions to improve disrupted rest-activity patterns and disturbed behavior in people with dementia is an important research goal. Here we report a proof-of-concept study which evaluates the effect an...
Relative light sensitivities of four retinal hemi-fields for suppressing the synthesis of melatonin at night [0.03%]
四种视网膜半视野相对于抑制夜间褪黑素合成的相对光敏感度
Mark S Rea,Rohan Nagare,Mariana G Figueiro
Mark S Rea
The magnitude of the stimulus to the biological clock will depend upon the distribution of circadian phototransduction circuits across the retinae and the spatial distribution of luminous stimuli in the environment. The present study compar...