Human circadian rhythm studies: Practical guidelines for inclusion/exclusion criteria and protocol [0.03%]
人体生物钟研究：入组/排除标准及实验方案制定实用指南
Yashar Yousefzadehfard,Bennett Wechsler,Christine DeLorenzo
Yashar Yousefzadehfard
As interest in circadian rhythms and their effects continues to grow, there is an increasing need to perform circadian studies in humans. Although the constant routine is the gold standard for these studies, there are advantages to performi...
Endogenous opioid signaling in the retina modulates sleep/wake activity in mice [0.03%]
小鼠视网膜内源性阿片类信号传导调节清醒状态和睡眠状态活动
Casey-Tyler Berezin,Nikolas Bergum,Kes A Luchini et al.
Casey-Tyler Berezin et al.
Circadian sleep/wake rhythms are synchronized to environmental light/dark cycles in a process known as photoentrainment. We have previously shown that activation of β-endorphin-preferring μ-opioid receptors (MORs) inhibits the light-evoke...
Sex differences in the diathetic effects of shift work schedules on circulating cytokine levels and pathological outcomes of ischemic stroke during middle age [0.03%]
轮班工作对中年时期缺血性卒中发病的易感效应及细胞因子水平的性别差异研究
David J Earnest,Shaina Burns,Sivani Pandey et al.
David J Earnest et al.
Shift work is associated with increased risk for vascular disease, including stroke- and cardiovascular-related mortality. However, evidence from these studies is inadequate to distinguish the effect of altered circadian rhythms in isolatio...
REM sleep promotes bidirectional plasticity in developing visual cortex in vivo [0.03%]
快速眼动睡眠促进视觉皮层发育中的双向可塑性
Leslie Renouard,Christopher Hayworth,Michael Rempe et al.
Leslie Renouard et al.
Sleep is required for the full expression of plasticity during the visual critical period (CP). However, the precise role of rapid-eye-movement (REM) sleep in this process is undetermined. Previous studies in rodents indicate that REM sleep...
Sleep disorders among Aboriginal Australians with Machado-Joseph Disease: Quantitative results from a multiple methods study to assess the experience of people living with the disease and their caregivers [0.03%]
澳大利亚马查多-约瑟夫病患者的睡眠障碍：定量研究结果，该研究采用多种方法评估患病人群及其照顾者的经历
Desireé LaGrappe,Libby Massey,Anuk Kruavit et al.
Desireé LaGrappe et al.
Background: Machado-Joseph Disease (MJD), or Spinocerebellar Ataxia Type 3 (SCA3), is a genetic disorder that causes progressive muscle weakness, loss of motor control, ataxia and permanent physical disability. Sleep dist...
Microglia are involved in the protection of memories formed during sleep deprivation [0.03%]
小胶质细胞参与睡眠剥夺期间形成的记忆的保护作用
Nicholas W Gentry,Thomas McMahon,Maya Yamazaki et al.
Nicholas W Gentry et al.
Sleep deprivation can generate inflammatory responses in the central nervous system. In turn, this inflammation increases sleep drive, leading to a rebound in sleep duration. Microglia, the innate immune cells found exclusively in the CNS, ...
A randomized controlled trial on the effect of blue-blocking glasses compared to partial blue-blockers on melatonin profile among nulliparous women in third trimester of the pregnancy [0.03%]
一项关于孕妇晚间使用蓝光过滤眼镜和普通眼镜对体内褪黑素水平影响的随机对照实验研究
Randi Liset,Janne Grønli,Roger Ekeberg Henriksen et al.
Randi Liset et al.
Objective: In pregnancy melatonin regulates circadian rhythms, induce sleep, and has a neuroprotective positive effect on fetal development. Artificial blue light in the evening delays and suppresses melatonin production....
Amount of < 1Hz deep sleep correlates with melatonin dose in military veterans with PTSD [0.03%]
一赫兹以下深度睡眠量与患有创伤后应激障碍的退伍军人褪黑激素剂量相关
Julie Onton,Lu D Le
Julie Onton
Military veterans with posttraumatic stress disorder often complain of non-restful sleep, which further exacerbates their symptoms. Our previous study showed a deficit in Lo Deep sleep, or slow oscillations, in the PTSD population compared ...
Chronic methamphetamine uncovers a circadian rhythm in multiple-unit neural activity in the dorsal striatum which is independent of the suprachiasmatic nucleus [0.03%]
慢性甲基苯丙胺会诱发黑质多巴胺能神经元的昼夜节律性胞外多巴胺浓度变化
Shota Miyazaki,Yu Tahara,Christopher S Colwell et al.
Shota Miyazaki et al.
The dorsal striatum forms part of the basal ganglia circuit that is a major regulator of voluntary motor behavior. Dysfunction in this circuit is a critical factor in the pathology of neurological (Parkinson's and Huntington's disease) as w...
Spatial sensitivity of human circadian response: Melatonin suppression from on-axis and off-axis light exposures [0.03%]
人circadian反应的空间敏感度：轴向和非轴向光源照射造成的褪黑素抑制
Rohan Nagare,Mark S Rea,Mariana G Figueiro
Rohan Nagare
A better understanding of the spatial sensitivity of the human circadian system to photic stimulation can provide practical solutions for optimized circadian light exposures. Two psychophysical experiments, involving 25 adult participants i...