Kiyomichi Imamura,Toru Takumi
Kiyomichi Imamura
Many physiological functions with approximately 24-h rhythmicity (circadian rhythms) are generated by an internal time-measuring system of the circadian clock. While sleep/wake cycles, feeding patterns, and body temperature are the most wid...
Gareth Banks,Patrick M Nolan,Nora Bourbia
Gareth Banks
Shift work (work outside of standard daylight hours) is common throughout the Western world. However, there are notable health consequences to shift work, including increased prevalence of mental health and sleep disorders in shift worker p...
Explicit memory, anxiety and depressive like behavior in mice exposed to chronic intermittent hypoxia, sleep fragmentation, or both during the daylight period [0.03%]
慢性间歇性缺氧、睡眠片段化或两者兼有的白天暴露对小鼠显性记忆、焦虑和类似抑郁行为的影响
Clementine Puech,Mohammad Badran,Alexandra R Runion et al.
Clementine Puech et al.
Obstructive sleep apnea (OSA) is a chronic and highly prevalent condition characterized by chronic intermittent hypoxia (IH) and sleep fragmentation (SF), and can lead to a vast array of end-organ morbidities, particularly affecting cardiov...
The rat Lux Actuating Search Task (LAST) and effects of sleep deprivation on task reversal performance [0.03%]
大鼠Lux操作行为搜索任务（LAST）及睡眠剥夺对任务转换性能的影响
Callum Foakes,Darian Lawrence-Sidebottom,Aseru T Dralega et al.
Callum Foakes et al.
Sleep deprivation (SD) causes significant deficits in multiple aspects of cognition, including sustained attention and working memory. Investigating the neural processes underpinning these cognitive losses has proven challenging due to the ...
Human circadian rhythm studies: Practical guidelines for inclusion/exclusion criteria and protocol [0.03%]
人体生物钟研究：入组/排除标准及实验方案制定实用指南
Yashar Yousefzadehfard,Bennett Wechsler,Christine DeLorenzo
Yashar Yousefzadehfard
As interest in circadian rhythms and their effects continues to grow, there is an increasing need to perform circadian studies in humans. Although the constant routine is the gold standard for these studies, there are advantages to performi...
Endogenous opioid signaling in the retina modulates sleep/wake activity in mice [0.03%]
小鼠视网膜内源性阿片类信号传导调节清醒状态和睡眠状态活动
Casey-Tyler Berezin,Nikolas Bergum,Kes A Luchini et al.
Casey-Tyler Berezin et al.
Circadian sleep/wake rhythms are synchronized to environmental light/dark cycles in a process known as photoentrainment. We have previously shown that activation of β-endorphin-preferring μ-opioid receptors (MORs) inhibits the light-evoke...
Sex differences in the diathetic effects of shift work schedules on circulating cytokine levels and pathological outcomes of ischemic stroke during middle age [0.03%]
轮班工作对中年时期缺血性卒中发病的易感效应及细胞因子水平的性别差异研究
David J Earnest,Shaina Burns,Sivani Pandey et al.
David J Earnest et al.
Shift work is associated with increased risk for vascular disease, including stroke- and cardiovascular-related mortality. However, evidence from these studies is inadequate to distinguish the effect of altered circadian rhythms in isolatio...
REM sleep promotes bidirectional plasticity in developing visual cortex in vivo [0.03%]
快速眼动睡眠促进视觉皮层发育中的双向可塑性
Leslie Renouard,Christopher Hayworth,Michael Rempe et al.
Leslie Renouard et al.
Sleep is required for the full expression of plasticity during the visual critical period (CP). However, the precise role of rapid-eye-movement (REM) sleep in this process is undetermined. Previous studies in rodents indicate that REM sleep...
Sleep disorders among Aboriginal Australians with Machado-Joseph Disease: Quantitative results from a multiple methods study to assess the experience of people living with the disease and their caregivers [0.03%]
澳大利亚马查多-约瑟夫病患者的睡眠障碍：定量研究结果，该研究采用多种方法评估患病人群及其照顾者的经历
Desireé LaGrappe,Libby Massey,Anuk Kruavit et al.
Desireé LaGrappe et al.
Background: Machado-Joseph Disease (MJD), or Spinocerebellar Ataxia Type 3 (SCA3), is a genetic disorder that causes progressive muscle weakness, loss of motor control, ataxia and permanent physical disability. Sleep dist...
Microglia are involved in the protection of memories formed during sleep deprivation [0.03%]
小胶质细胞参与睡眠剥夺期间形成的记忆的保护作用
Nicholas W Gentry,Thomas McMahon,Maya Yamazaki et al.
Nicholas W Gentry et al.
Sleep deprivation can generate inflammatory responses in the central nervous system. In turn, this inflammation increases sleep drive, leading to a rebound in sleep duration. Microglia, the innate immune cells found exclusively in the CNS, ...