Extracting continuous sleep depth from EEG data without machine learning [0.03%]
无需机器学习的连续EEG睡眠深度提取算法研究
Claus Metzner,Achim Schilling,Maximilian Traxdorf et al.
Claus Metzner et al.
The human sleep-cycle has been divided into discrete sleep stages that can be recognized in electroencephalographic (EEG) and other bio-signals by trained specialists or machine learning systems. It is however unclear whether these human-de...
Sleep disturbances in autism spectrum disorder: Animal models, neural mechanisms, and therapeutics [0.03%]
自闭症谱系障碍的睡眠紊乱：动物模型、神经机制和治疗措施
John J Maurer,Ashley Choi,Isabella An et al.
John J Maurer et al.
Sleep is crucial for brain development. Sleep disturbances are prevalent in children with autism spectrum disorder (ASD). Strikingly, these sleep problems are positively correlated with the severity of ASD core symptoms such as deficits in ...
Circadian profile, daytime activity, and the Parkinson's phenotype: A motion sensor pilot study with neurobiological underpinnings [0.03%]
昼夜节律、日间活动与帕金森表型：具有神经生物学基础的运动传感器试点研究
Massimo Marano,Jessica Rosati,Alessandro Magliozzi et al.
Massimo Marano et al.
Circadian rhythm impairment may play a role in Parkinson's disease (PD) pathophysiology. Recent literature associated circadian rhythm features to the risk of developing Parkinson and to its progression through stages. The association betwe...
Christine M Muheim,Kaitlyn Ford,Elizabeth Medina et al.
Christine M Muheim et al.
Sleep deprivation (SD) results in profound cellular and molecular changes in the adult mammalian brain. Some of these changes may result in, or aggravate, brain disease. However, little is known about how SD impacts gene expression in devel...
Elpidio Attoh-Mensah,Ivan Igor-Gaez,Lydie Vincent et al.
Elpidio Attoh-Mensah et al.
The autonomic nervous system (ANS) and the central nervous system (CNS) interplay during sleep, particularly during phasic events such as micro-arousals, has been the subject of several studies. The underlying mechanisms of such relationshi...
Repetitive mild traumatic brain injury alters central and peripheral clock gene expression in the adolescent rat [0.03%]
重复的轻度脑创伤会改变青春期大鼠中枢和外周生物钟基因表达
Marissa Sgro,Susanne Ellens,Zoe N Kodila et al.
Marissa Sgro et al.
Mild traumatic brain injury (mTBI) or concussion is a common injury worldwide leading to substantial medical costs and a high burden on society. In adolescents, falls and sports related trauma are often the causes of mTBI. Importantly, crit...
Activation of mGluR1 negatively modulates glutamate-induced phase shifts of the circadian pacemaker in the mouse suprachiasmatic nucleus [0.03%]
鼠视交叉上核中mGluR1的激活负向调节谷氨酸诱导的昼夜节律起搏器的相位变化
Yoon Sik Kim,C Justin Lee,Ji-Hyeon Kim et al.
Yoon Sik Kim et al.
In mammals, photic information delivered to the suprachiasmatic nucleus (SCN) via the retinohypothalamic tract (RHT) plays a crucial role in synchronizing the master circadian clock located in the SCN to the solar cycle. It is well known th...
Early life sleep disruption has long lasting, sex specific effects on later development of sleep in prairie voles [0.03%]
草原田鼠早期生活期的睡眠紊乱对其后期睡眠发展的影响持续时间长且性别特异化
Carolyn E Jones-Tinsley,Randall J Olson,Miranda Mader et al.
Carolyn E Jones-Tinsley et al.
In mammals, sleep duration is highest in the early postnatal period of life and is critical for shaping neural circuits that control the development of complex behaviors. The prairie vole is a wild, highly social rodent that serves as a uni...
Elizabeth Medina,Sarah Peterson,Kaitlyn Ford et al.
Elizabeth Medina et al.
Brain development relies on both experience and genetically defined programs. Time windows where certain brain circuits are particularly receptive to external stimuli, resulting in heightened plasticity, are referred to as "critical periods...
Loss of sleep when it is needed most - Consequences of persistent developmental sleep disruption: A scoping review of rodent models [0.03%]
最需要时却无法获得睡眠-持续发展性睡眠干扰的后果：啮齿动物模型的范围审查
Noah E P Milman,Carolyn E Tinsley,Ravikiran M Raju et al.
Noah E P Milman et al.
Sleep is an essential component of development. Developmental sleep disruption (DSD) impacts brain maturation and has been associated with significant consequences on socio-emotional development. In humans, poor sleep during infancy and ado...