Comparison of the macro and microstructure of sleep in a sample of sleep clinic hypersomnia cases [0.03%]
睡眠诊所嗜睡症患者的睡眠宏观和微观结构比较研究
Alyssa Cairns,Richard Bogan
Alyssa Cairns
The purpose of this study was to elucidate the differentiating or grouping EEG characteristics in various hypersomnias (type 1 and type 2 narcolepsy (N-1 and N-2) and idiopathic hypersomnia (IH) compared to an age-matched snoring reference ...
Negin Sattari,Lauren N Whitehurst,Maryam Ahmadi et al.
Negin Sattari et al.
Working Memory (WM), is an important factor influencing many higher-order cognitive functions that decline with age. Repetitive training appears to increase WM, yet the mechanisms underlying this improvement are not understood. Sleep has be...
Brain dynamics during the sleep onset transition: An EEG source localization study [0.03%]
睡眠过渡期的脑动力学研究：一项EEG源定位研究
Antonio Fernandez Guerrero,Peter Achermann
Antonio Fernandez Guerrero
EEG source localization is an essential tool to reveal the cortical sources underlying brain oscillatory activity. We applied LORETA, a technique of EEG source localization, to identify the principal brain areas involved in the process of f...
Electrophysiological characterization of sleep/wake, activity and the response to caffeine in adult cynomolgus macaques [0.03%]
咖啡因对成人猕猴睡眠/清醒和活动的影响及其反应的电生理特征研究
Anushka V Goonawardena,Stephen R Morairty,Gabriel A Orellana et al.
Anushka V Goonawardena et al.
Most preclinical sleep studies are conducted in nocturnal rodents that have fragmented sleep in comparison to humans who are primarily diurnal, typically with a consolidated sleep period. Consequently, we sought to define basal sleep charac...
Investigating the relationships between hypothalamic volume and measures of circadian rhythm and habitual sleep in premanifest Huntington's disease [0.03%]
探究下丘脑体积与昼夜节律和习惯性睡眠在亨廷顿舞蹈病前阶段的关系
Danielle M Bartlett,Juan F Domínguez D,Alvaro Reyes et al.
Danielle M Bartlett et al.
Objective: Pathological changes within the hypothalamus have been proposed to mediate circadian rhythm and habitual sleep disturbances in individuals with Huntington's disease (HD). However, investigations examining the r...
Sex hormones play a role in vulnerability to sleep loss on emotion processing tasks [0.03%]
性激素在睡眠丧失对情绪处理任务的易感性中起作用
K A Lustig,E M Stoakley,K J MacDonald et al.
K A Lustig et al.
The central aim of this study was to investigate hormones as a predictor of individual vulnerability or resiliency on emotion processing tasks following one night of sleep restriction. The restriction group was instructed to sleep 3 a.m.-7 ...
Theresa E Bjorness,Robert W Greene
Theresa E Bjorness
Chronic cocaine use has been associated with sleep disturbances, both during active use periods and during withdrawal and abstinence. Acute cocaine also increases waking at the expense of slow wave sleep and Rapid Eye Movement in non-human ...
Chronic circadian advance shifts abolish melatonin secretion for days in rats [0.03%]
慢性昼夜提前移位会导致大鼠数日内不再分泌松果体素
Gang Xu,Jon Dean,Tiecheng Liu et al.
Gang Xu et al.
Melatonin deficiency has been proposed to underlie higher risks for cardiovascular and several other diseases in humans experiencing prolonged shiftwork. However, melatonin secretion has not been monitored longitudinally during consecutive ...
Sleep homeostasis and the circadian clock: Do the circadian pacemaker and the sleep homeostat influence each other's functioning? [0.03%]
睡眠稳态和生物钟：昼夜起搏器和睡眠稳态调节机制相互影响吗？
Tom Deboer
Tom Deboer
Sleep is regulated by a homeostatic and a circadian process. Together these two processes determine most aspects of sleep and related variables like sleepiness and alertness. The two processes are known to be able to work independently, but...
Reflections on contributing to "big discoveries" about the fly clock: Our fortunate paths as post-docs with 2017 Nobel laureates Jeff Hall, Michael Rosbash, and Mike Young [0.03%]
与2017年诺贝尔奖得主杰弗理·霍尔、迈克尔·罗索和迈克尔·杨合作感悟：作为博士后的幸运之路
Kathleen K Siwicki,Paul E Hardin,Jeffrey L Price
Kathleen K Siwicki
In the early 1980s Jeff Hall and Michael Rosbash at Brandeis University and Mike Young at Rockefeller University set out to isolate the period (per) gene, which was recovered in a revolutionary genetic screen by Ron Konopka and Seymour Benz...