Noushin Hadadi,Vincent Berweiler,Haiping Wang et al.
Noushin Hadadi et al.
The deficiency of micronutrients, including vitamins and minerals, is estimated to affect two billion people worldwide and can have devastating immediate and long-term consequences. Major causes range from inadequate micronutrient consumpti...
The intestinal microbiota and anorexia nervosa: cause or consequence of nutrient deprivation [0.03%]
肠道微生物群和神经性厌食症：营养缺乏的原因或结果？
Kylie K Reed,Afrouz Abbaspour,Cynthia M Bulik et al.
Kylie K Reed et al.
The intestinal microbiota is a diverse microbial community that colonizes the gastrointestinal tract of animals. Abnormal changes in intestinal microbiota has been associated with multiple diseases including inflammatory bowel diseases and ...
Cheryl S Rosenfeld
Cheryl S Rosenfeld
Endocrine disrupting chemicals (EDCs) that act as xenoestrogens are natural and synthetic chemicals widely present in food products, industrial products, and the environment. Such compounds can activate or inhibit normal hormonal pathways b...
Susan Sam,Esra Tasali
Susan Sam
Women with polycystic ovary syndrome (PCOS) have a substantially increased risk for diabetes and cardiovascular disease. Obstructive sleep apnea (OSA) is the most common sleep disorder in PCOS. Recent population-based studies indicate a hig...
Skand Shekhar,Janet E Hall,Joanna Klubo-Gwiezdzinska
Skand Shekhar
Sleep has a bidirectional relationship with the hypothalamic-pituitary-thyroid (HPT) axis, and both these homeostatic processes are inter-dependent for robust physiological functioning. The quality and quantity of sleep influence the circad...
Emulating the gut-liver axis: Dissecting the microbiome's effect on drug metabolism using multiorgan-on-chip models [0.03%]
模拟肠肝轴：使用多器官芯片模型解析微生物组对药物代谢的影响
Mara Lucchetti,Mathilda Kaminska,Aina Kehinde Oluwasegun et al.
Mara Lucchetti et al.
The homeostatic relationship between the gut, its microbiome, and the liver is crucial for the regulation of drug metabolism processes. Gut microbes are known to influence human health and disease by enhancing food metabolism and providing ...
Pediatric nonalcoholic fatty liver disease and the microbiome: Mechanisms contributing to pathogenesis and progression [0.03%]
儿童非酒精性脂肪肝与微生物组：参与发病和进展的机制
Nita H Salzman,Jeffrey B Schwimmer
Nita H Salzman
Nonalcoholic fatty liver disease (NAFLD) is the most common form of pediatric liver disease in the United States, and often associated with obesity and metabolic syndrome. NAFLD comprises a broad spectrum of liver diseases, from hepatic ste...
Calcium-sensing receptor signaling - How human disease informs biology [0.03%]
钙感受器信号转导研究——从人类疾病探索生命科学
Caroline M Gorvin
Caroline M Gorvin
The calcium-sensing receptor (CaSR) is a class C G-protein-coupled receptor (GPCR) that plays a fundamental role in extracellular calcium homeostasis by regulating parathyroid hormone (PTH) release. Although the CaSR was identified over 25 ...
Kathleen Van Dyk,Hadine Joffe,Judith E Carroll
Kathleen Van Dyk
Sleep disturbances and insomnia are common among breast cancer survivors, and can have a significant effect on quality of life and numerous other significant outcomes. Among risks for sleep disturbance is the introduction of anti-estrogen e...
Jessica M O&#x;Connell,Melissa E Pepling
Jessica M O&#x;Connell
Formation of primordial follicles occurs when germ cell nests break apart and individual oocytes become surrounded by pregranulosa cells. Why mammalian germ cells develop in germ cell nests is not fully understood but recent work has provid...