Recent progress in analyzing the spatial structure of the human microbiome: distinguishing biogeography and architecture in the oral and gut communities [0.03%]
近期关于人类微生物组空间结构分析的研究进展:口腔及肠道菌群生物地理学与建筑学的区别
Emmanuel E Adade,Khalid Al Lakhen,Alex A Lemus et al.
Emmanuel E Adade et al.
Fueled by technological advances in methods for sample collection and preservation in sequencing studies, and in advances in computational analyses of high content image data, the spatial structure of the human microbiome is coming to light...
Cause or consequence? Understanding the role of cortisol in the increased inflammation observed in depression [0.03%]
起因或后果?认识皮质醇在抑郁症中观察到的炎症增加中的作用
Nare Amasi-Hartoonian,Luca Sforzini,Annamaria Cattaneo et al.
Nare Amasi-Hartoonian et al.
Glucocorticoids such as cortisol are a class of steroid hormones that play an important role in co-ordinating the body's response to stress. Elevated cortisol levels and increased inflammation have frequently been reported in patients with ...
The Influence of Diet on Metabolism and Health Across the Lifespan in Nonhuman Primates [0.03%]
非人灵长类动物一生中饮食对代谢和健康的影响
Elizabeth K Wood,Elinor L Sullivan
Elizabeth K Wood
The macro and micronutrient composition and the overall quantity of the diet are important predictors of physical and psychological health and, as a consequence, behavior. Translational preclinical models are critical to identifying the mec...
Colin J Saldanha
Colin J Saldanha
Glial cells are important contributors to the hormonal milieu of the brain, particularly following damage. In birds and mammals, neural injury induces the expression of aromatase in astroglia at and around the site of damage. This review de...
Nora A OByrne,Fiona Yuen,Waleed Z Butt et al.
Nora A OByrne et al.
The central circadian pacemaker (CCP) located in the suprachiasmatic nucleus (SCN) of the hypothalamus drives the 24-hour pattern in cortisol, which functions as the main central synchronizing signal that coordinates peripheral clocks in or...
Nicholas Dietrich,Jackson A Hoffman,Trevor K Archer
Nicholas Dietrich
Breast cancers are a diverse group of diseases and are often characterized by their expression of receptors for hormones such as estrogen and progesterone. Recently another steroid hormone receptor, the glucocorticoid receptor (GR) has been...
Janet N Lucien,Madison T Ortega,Natalie D Shaw
Janet N Lucien
In the 1970's, Boyar and colleagues made the seminal observation that during the early stages of puberty, there is a sleep-specific augmentation of pulsatile luteinizing hormone (LH) secretion. Building on this tantalizing association betwe...
Judith E Carroll,Aric A Prather
Judith E Carroll
Obtaining healthy quantity and quality of sleep is a key to optimal mental and physical health, and cumulative evidence points to a role of sleep loss and sleep disturbances as a contributor to early disease onset and shortened survival. We...
Sleep and Circadian Disruption and the Gut Microbiome-Possible Links to Dysregulated Metabolism [0.03%]
睡眠和生物节律紊乱与肠道菌群—可能与失调的代谢有关
Dana Withrow,Samuel J Bowers,Christopher M Depner et al.
Dana Withrow et al.
Insufficient sleep and circadian misalignment are associated with adverse metabolic health outcomes. Alterations in gut microbial diversity occur with insufficient sleep and circadian misalignment, which can lead to modifications in microbi...
Bethany K Patton,Surabhi Madadi,Stephanie A Pangas
Bethany K Patton
The reproductive lifespan of female mammals is limited and ultimately depends on the production of a sufficient number of high quality oocytes from a pool of non-growing primordial follicles that are set aside during embryonic and perinatal...