Heather Wachtel,Katherine L Nathanson
Heather Wachtel
Pheochromocytomas and paragangliomas (PPGL) are neuroendocrine tumors which secrete catecholamines, causing cardiovascular compromise. While isolated tumors and locoregional disease can be treated surgically, treatment options for metastati...
Metabolic small talk during exercise: The role of metabokines and lipokines in interorgan signalling [0.03%]
运动时的代谢小对话：代谢激素和脂质激素在器官间信号传递中的作用
Shaimaa A Gad,Hannah Smith,Lee D Roberts
Shaimaa A Gad
Metabolites in exercise have traditionally been viewed as a fuel source, waste product, or anabolic components required for exercise-induced biosynthetic processes. However, it is now recognised that metabolites and lipids may act as mediat...
Ruth Andrew,Roland H Stimson
Ruth Andrew
Hormones regulate metabolic homeostasis through interlinked dynamic networks of proteins and small molecular weight metabolites, and state-of-the-art chemical technologies have been developed to decipher these complex pathways. Stable-isoto...
Fiona L Roberts,Vicky E MacRae
Fiona L Roberts
Recent advancements in the bone biology field have identified a novel bone-metabolism axis. In this review, we highlight several novel studies that further our knowledge of new endocrine functions of bone; explore remaining unanswered quest...
Recent advances in understanding hypothalamic control of defensive responses to hypoglycaemia [0.03%]
近年来低血糖防御反应下丘脑调控研究的进展
Emily O Staricoff,Mark L Evans
Emily O Staricoff
Maintenance of normal blood glucose is important for survival. In particular, brain function is dependent on circulating glucose. In health, a series of powerful counterregulatory defences operate to prevent/limit hypoglycaemia. These defen...
Gregory J Pazour
Gregory J Pazour
Ciliary dysfunction causes a large group of developmental and degenerative human diseases known as ciliopathies. These diseases reflect the critical roles that cilia play in sensing the environment and in force generation for motility. Sens...
Samantha E Adamson,Jing W Hughes
Samantha E Adamson
The primary cilium is a sensory and signaling organelle present on most pancreatic islet endocrine cells, where it receives and interprets a wide range of intra-islet chemical cues including hormones, peptides, and neurotransmitters. The ci...
Freddy Jeanneteau,Laurence Coutellier
Freddy Jeanneteau
The complexity of the classical inverted U-shaped relationship between cortisol levels and responses transposable to stress reactivity has led to an incomplete understanding of the mechanisms enabling healthy and toxic effects of stress on ...
Mark I Hunter,Karen M Thies,Wipawee Winuthayanon
Mark I Hunter
This review intends to bridge the gap between our knowledge of steroid hormone regulation of motile cilia and the potential involvement of the primary cilium focusing on the female reproductive tract functions. The review emphasizes hormona...
Laura M Harrison,Jeffrey G Tasker
Laura M Harrison
Glucocorticoids exert pleiotropic effects either by a relatively slow mechanism involving binding to cytosolic/nuclear receptors and regulation of gene expression or by rapid activation of a putative membrane receptor and membrane signal tr...