Charge Transfer between [4Fe4S] Proteins and DNA Is Unidirectional: Implications for Biomolecular Signaling [0.03%]
[4Fe4S]蛋白与DNA之间的电荷转移是单向的：其对生物分子信号转导的意义
Ruijie D Teo,Benjamin J G Rousseau,Elizabeth R Smithwick et al.
Ruijie D Teo et al.
Recent experiments suggest that DNA-mediated charge transport might enable signaling between the [4Fe4S] clusters in the C-terminal domains of human DNA primase and polymerase α, as well as the signaling between other replication and repai...
Supramolecular Chemistry of Anionic Dimers, Trimers, Tetramers and Clusters [0.03%]
阴离子二聚体、三聚体、四聚体及聚合物的超分子化学
Qing He,Peiyu Tu,Jonathan L Sessler
Qing He
Two or more anions constrained in close proximity within a single pocket are found in a number of natural systems but a less common motif in artificial systems. This review summarizes work on anion receptors capable of stabilizing anionic d...
A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases [0.03%]
细菌蛋白质酪氨酸磷酸酶中的半胱氨酸-半胱氨酸氧化还原调节机制——含水桥梁式结构的发现及其催化作用研究
Jean B Bertoldo,Tiago Rodrigues,Lavinia Dunsmore et al.
Jean B Bertoldo et al.
The emergence of multidrug-resistant Mycobacterium tuberculosis (Mtb) strains highlights the need to develop more efficacious and potent drugs. However, this goal is dependent on a comprehensive understanding of Mtb virulence protein effect...
Bright long-lived luminescence of silicon nanocrystals sensitized by two-photon absorbing antenna [0.03%]
由两光子吸收天线敏化的硅量子点的明亮而持久的发光性研究
Luca Ravotto,Qi Chen,Yuguo Ma et al.
Luca Ravotto et al.
Silicon nanocrystals of the average diameter of 5 nm, functionalized with 4,7-di(2-thienyl)-2,1,3-benzothiadiazole chromophores (TBT) and dodecyl chains, exhibit near-infrared emission upon one-photon (1P) excitation at 515 nm and two-photo...
Jessica L Cleary,Alanna R Condren,Katherine E Zink et al.
Jessica L Cleary et al.
Bacteria are cosmopolitan organisms that in recent years have demonstrated many roles in maintaining host equilibrium. In this review, we discuss three roles bacteria can occupy in a host: pathogenic, symbiotic, and transient, with a specif...
Laura Riccardi,Luca Gabrielli,Xiaohuan Sun et al.
Laura Riccardi et al.
The self-assembly of a monolayer of ligands on the surface of noble-metal nanoparticles dictates the fundamental nanoparticle's behavior and its functionality. In this combined computational-experimental study, we analyze the structure, org...
Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery [0.03%]
UiO-66纳米粒子的选择性表面peg化以增强稳定性，细胞摄取和pH响应药物输送性能
Isabel Abánades Lázaro,Salame Haddad,Sabrina Sacca et al.
Isabel Abánades Lázaro et al.
The high storage capacities and excellent biocompatibilities of metal-organic frameworks (MOFs) have made them emerging candidates as drug-delivery vectors. Incorporation of surface functionality is a route to enhanced properties, and here ...
Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on a Kilogram Scale [0.03%]
基于吡啶-N-氧化物的光化学全氟烷基化反应：机理研究与公斤规模应用
Joel W Beatty,James J Douglas,Richard Miller et al.
Joel W Beatty et al.
The direct trifluoromethylation of (hetero)arenes is a process of high importance to the pharmaceutical industry. Many reagents exist for this purpose and have found widespread use in discovery efforts; however, the step-intensive preparati...
Enzyme-Instructed Self-Assembly for Spatiotemporal Profiling of the Activities of Alkaline Phosphatases on Live Cells [0.03%]
活细胞上碱性磷酸酶活性时空分析的酶触发分子自组装技术
Jie Zhou,Xuewen Du,Cristina Berciu et al.
Jie Zhou et al.
Alkaline phosphatase (ALP), an ectoenzyme, plays important roles in biology. But there is no activity probes for imaging ALPs in live cell environment due to the diffusion and cytotoxicity of current probes. Here we report the profiling of ...
Hierarchical Self-Assembly of Halogen-Bonded Block Copolymer Complexes into Upright Cylindrical Domains [0.03%]
卤素键嵌段共聚物复合物自组装形成垂直柱状区域的分层结构
Roberto Milani,Nikolay Houbenov,Francisco Fernandez-Palacio et al.
Roberto Milani et al.
Self-assembly of block copolymers into well-defined, ordered arrangements of chemically distinct domains is a reliable strategy for preparing tailored nanostructures. Microphase separation results from the system, minimizing repulsive inter...