Study protocol for a randomized controlled trial to pilot Restore Energy, Activity Can Help (REACH): an mHealth-enabled peer coaching intervention for fatigue in systemic lupus erythematosus [0.03%]
一项随机对照试验的研究方案：针对系统性红斑狼疮患者的疲劳感，试行恢复能量、活动有助（REACH）mHealth赋能同伴辅导干预措施
Nina Gulati,Kiran Singh,Erin Morrissey et al.
Nina Gulati et al.
Background: Fatigue affects up to 90 % of individuals with systemic lupus erythematosus (SLE), significantly impairing quality of life. Despite its impact, fatigue remains difficult to treat due to its multifactorial natu...
Information seeking by participants enrolled in randomized clinical trials of behavioral interventions [0.03%]
行为干预随机临床试验受试者的信息搜寻行为研究
Kathryn M Ross,Kelsey M Arroyo,Megan A McVay
Kathryn M Ross
Background: Little is known regarding information seeking by participants in randomized clinical trials (RCTs) of behavioral interventions. The current study explored the prevalence of information seeking, whether informa...
Increasing Resiliency in U.S. Air Force Personnel: A Multi-Site Trial Protocol [0.03%]
美国空军人员韧性的增强：一项多中心试验方案
Stephen H A Hernandez,Jacqueline Killian,Mark B Parshall et al.
Stephen H A Hernandez et al.
The purpose of this study is to examine the efficacy of the Stress Management and Resilience Training (SMART) in increasing the resilience of U.S. Air Force personnel. We aim to recruit up to 500 active component Air Force personnel and pro...
Phase 1 clinical trial on Orgasmic Meditation (OM): Assessing safety and feasibility as a meditation practice for individuals with PTSD [0.03%]
关于性高潮冥想的I期临床试验：评估其作为创伤后应激障碍个体冥想实践的安全性和可行性
Daniel Kriegman,Rachel Pelletier,Caroline Griggs et al.
Daniel Kriegman et al.
Background: We measured the safety and efficacy of a treatment protocol that includes Orgasmic Meditation (OM), a structured attention training practice conducted between two people who follow a predefined set of detailed...
Corrigendum to "Protocol for a randomized clinical trial of strength at home parents: A trauma informed parenting intervention for veterans" [Contempor. Clin. Trials Commun. 41 (2024) 101363] [0.03%]
关于“家庭父母力量协议：一项针对退伍军人的创伤知情育儿干预的随机临床试验方案”的勘误表[当代临床试验通讯. 41 (2024) 101363]
Rahel Pearson,Paul J Rathouz,Corina Mendoza et al.
Rahel Pearson et al.
[This corrects the article DOI: 10.1016/j.conctc.2024.101363.].
A clinic-based healthcare transition preparation program for adolescents and young adults with type 1 diabetes: Study protocol for the SHIFT randomized clinical trial [0.03%]
基于门诊的青少年和年轻成人1型糖尿病医疗过渡准备计划：SHIFT随机临床试验研究方案
Laura J Caccavale,Randi Streisand,Jessica Gokee LaRose et al.
Laura J Caccavale et al.
Background: A striking 83 % of adolescents and young adults (AYA) with type 1 diabetes (T1D) have glycemic outcomes outside the target range, placing them at risk for acute and chronic complications. Identification of evi...
Automated protocol templates with efficient schedule of activities table generation for healthy volunteer trials [0.03%]
自动化协议模板及高效生成健康志愿者试验活动计划表
Kyongeun Shin,Sungpil Han,Hyerim Choe et al.
Kyongeun Shin et al.
Background: The writing of clinical trial protocols that conform to relevant guidelines is a labor- and time-intensive endeavor. An automated clinical trial protocol template generation system for healthy volunteer trials...
Efficacy and safety of SARS-CoV-2 neutralizing antibody, SCTA01, in high-risk outpatients diagnosed with COVID-19: A Phase II clinical trial [0.03%]
SCTA01抗新冠病毒中和抗体治疗高风险门诊新冠肺炎患者的疗效和安全性：II期临床试验
Jorge Diaz,Allex Fonseca,Lixin Yan et al.
Jorge Diaz et al.
Background/objective: The neutralizing monoclonal antibody against SARS-CoV-2 is regarded as one of the most effective therapies for COVID-19.: This study was a randomized, double-blinded, placebo-controlled Phase II tria...
SHengXIaN-QuYu DEcoction in the Treatment of Heart Failure with Reduced and Mildly-Reduced Ejection Fraction (SHINE-HF): rationale and design for a multicenter randomized controlled trial [0.03%]
参附苈泻汤治疗射血分数减低和轻度减低的心力衰竭（SHINE-HF）的临床研究方案：随机对照试验设计与质量控制措施
Lina Feng,Sizhen Chen,Jiang Liu et al.
Lina Feng et al.
Background: Although contemporary guideline-directed medical therapy (GDMT) for heart failure (HF) with reduced ejection fraction (HFrEF) and heart failure with mildly-reduced ejection fraction (HFmrEF) has been shown to ...
Therapeutic Yoga: A feasible complementary approach for glycemic control in individuals with impaired fasting glucose and elevated HbA1c [0.03%]
治疗性瑜伽：用于改善空腹血糖受损和糖化血红蛋白升高的个体血糖控制的可行辅助方法
Gitika Bhasin,Rucha S Dafale,K Annapoorna et al.
Gitika Bhasin et al.
Background: Impaired Fasting Glucose (IFG) with elevated glycated hemoglobin (HbA1c) is a key precursor to type 2 diabetes mellitus (T2DM). Although asymptomatic, IFG significantly raises the risk of developing T2DM and c...