Tackling burnout in Australian doctors by blending a web-based cognitive-behavioural therapy program with telehealth psychological support - protocol for a three-arm randomised-controlled trial [0.03%]
针对澳大利亚医生的职业倦怠所设计的结合远程心理支持和基于网络的认知行为疗法项目的干预措施——三臂随机对照试验方案
M J Coleshill,M J Black,K Luck et al.
M J Coleshill et al.
Background: Burnout has received limited attention in treatment programs, despite high prevalence among health professionals and the threat burnout places upon the mental health and the long-term sustainability of the Aus...
Virtual sailing exercise to improve major depressive disorder: A pilot clinical trial protocol [0.03%]
虚拟航行练习改善重度抑郁症的临床试验方案试点研究
Radietya Alvarabie,Yang Yun,Alexandra Gaillard et al.
Radietya Alvarabie et al.
Background: Major Depressive Disorder (MDD) is a prevalent and chronic psychiatric disorder associated with substantially reduced quality of life. However, current mental health management strategies- particularly for non...
Response variability to exercise (REVISE): Study rationale, design and methods [0.03%]
运动反应变化性（修订）研究合理性、设计与方法
Robert Ross,Andrew G Day,Paula J Stotz et al.
Robert Ross et al.
Physical inactivity and low levels of cardiorespiratory fitness (CRF, VO2peak) are major threats to public health. In response, leading health authorities worldwide recommend that all adults accumulate 150 min/wk of moderate to-vigorous phy...
Experience and lessons learned relating to investigational product supply in the design and delivery of a paediatric investigator-initiated clinical trial [0.03%]
与儿科研究者发起的临床试验的设计和交付相关的 Investigational Product 供应的经验和教训
Mandy Wan,Mark A Turner,Gilles Cambonie et al.
Mandy Wan et al.
The management of investigational product (IP) supply is a complex endeavour when designing and delivering clinical trials. In contrast to industry-sponsored trials where IP supplies are coordinated by teams of specialists working together ...
Using ecological momentary data to inform a web-based intervention for romantic partners concerned about their loved ones' drinking: Study protocol [0.03%]
基于生态时刻数据告知一种针对担心爱人酗酒的情侣的网络干预：研究计划
Lindsey M Rodriguez,Cynthia D Mohr,Katherine Nameth et al.
Lindsey M Rodriguez et al.
Concerned partners (CPs) play a crucial role in encouraging their loved ones to moderate or seek help for their drinking but are not always equipped with the strategies to approach these conversations effectively. This research comprises th...
Pilot optimization trial of a sexual and reproductive health program for Latina teens and their female caregivers: A study protocol [0.03%]
一项针对拉丁美洲少女及其女性监护人的性与生殖健康项目的试点优化试验：研究方案
Katherine G Merrill,Jacqueline Silva,Wendy Chu et al.
Katherine G Merrill et al.
Background: Latina teens experience sexual and reproductive health disparities; however, few effective interventions designed for Latina teens and their families exist. Floreciendo is a sexual and reproductive health inte...
Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH) [0.03%]
针对感染和脓毒症住院后的再入院减少方法的适应性试验的设计与方法（ACCOMPLISH）
Kristin Mayes,Victor B Talisa,Adelina Malito et al.
Kristin Mayes et al.
Background: The months following hospitalization for sepsis and lower respiratory tract infection can often be very difficult for patients. Many will have subsequent clinical deterioration, which for some requires hospita...
Study protocol for a pilot randomized trial building resiliency among caregivers of cancer curvivors and metavivors [0.03%]
增强癌症幸存者和Meta幸存者的照护者韧性试点随机试验方案
Brett M Goshe,Anna Barata,Lucy Finkelstein-Fox et al.
Brett M Goshe et al.
Background: Caregivers of cancer survivors experience chronic stress, increasing emotional and physical health risks. Many caregivers report unmet psychosocial needs and maladaptive coping strategies, resulting in high ca...
Intranasal insulin for the treatment of alcohol use disorder: design and methodology of an alcohol interaction randomized controlled trial [0.03%]
鼻用胰岛素治疗酒精使用障碍：一项酒精交互作用随机对照试验的设计与方法学
Carolina L Haass-Koffler,Bhavani Kashyap,Brian J Gully et al.
Carolina L Haass-Koffler et al.
Despite developments in treatments for alcohol use disorder (AUD), current pharmacotherapies face several limitations, including adverse events. Intranasal (IN) insulin has shown promise for addictive disorders. The overarching hypothesis o...
Assessing the efficacy of 3D window double screens (3D-WDS) in reducing malaria transmission in northeastern Tanzania: Study protocol for a two-arm cluster-randomised controlled trial [0.03%]
评估3D窗口双层帘帐在减少坦桑尼亚东北部地区疟疾传播方面的有效性：一项两臂集群随机对照试验的研究方案
William N Kisinza,Subam Kathet,Victor Mwingira et al.
William N Kisinza et al.
Background: The rise of insecticide resistance in malaria vectors has highlighted the urgent need for alternative vector control methods that do not rely on insecticides. The 3D-Screen, an innovative window screen featuri...