ASSIST in Pitjantjatjara: Protocol for a randomised crossover validation study among Aboriginal and Torres Strait Islander Australians [0.03%]
皮坦贾拉语ASSIST干预措施：一项在澳aboriginal和托雷斯海峡岛民中进行的随机对照试验方案
Matthew W R Stevens,Sue Bertossa,Dominic Barry et al.
Matthew W R Stevens et al.
Background: Substance use significantly contributes to disease burden among Australians, with harms exacerbated among Aboriginal and Torres Strait Islander peoples by colonisation-related factors like stigma and trauma. A...
Mindfulness vs. sleep education during autologous hematopoietic cell transplantation for multiple myeloma: Feasibility of a randomized controlled pilot study [0.03%]
自体造血细胞移植治疗多发性骨髓瘤患者正念练习和睡眠健康教育的可行性随机对照试点研究：一项平行分组试验
Elisabeth C Henley,Hannah A Liphart,Keayra J Morris et al.
Elisabeth C Henley et al.
Background: Sleep disturbance is common in patients receiving hematopoietic stem cell transplantation (HCT). Mindfulness-based interventions (MBIs) can improve sleep quality during and following cancer treatment by reduci...
Evaluating digital intervention approaches for supporting immigrant women with intimate partner violence experiences: Findings from the It's weWomen plus sequential multiple assignment randomized trial (SMART) [0.03%]
数字化干预方案在支持经历亲密伴侣暴力的移民女性中的效果评估——It's weWomen plus序贯多级随机试验(SMART)的结果分析
Bushra Sabri,Jian Li,Subhash Aryal et al.
Bushra Sabri et al.
Background: Intimate partner violence (IPV) disproportionately affects immigrant women, who often face barriers to accessing in-person services. Digital interventions offer a promising alternative by providing tailored, r...
DISYNCRO: Perceived roles of clinical study coordinators and data managers: results from a web-based survey of professionals from contract research organizations [0.03%]
临床研究协调员和数据管理专家的感知角色——来自合同研究组织专业人士网络调查的结果
Susanna Yedro,Elena Tinari,Daniele Napolitano et al.
Susanna Yedro et al.
Introduction: The evolution of clinical trials has made it essential to introduce specific roles, such as Clinical Study Coordinator (CSC) and Data Manager (DM), into the research process. Their responsibilities sometimes...
Evaluating the impact of the 'Blow, Breathe, Cough' health promotion intervention in resolving otitis media with effusion in children: An adaptive randomized-controlled trial protocol [0.03%]
评估“吹气、呼吸、咳嗽”健康促进干预措施对儿童分泌性中耳炎的疗效：一项适应性随机对照试验方案
Jaimee R Rich,Michael Dymock,Elke J Seppanen et al.
Jaimee R Rich et al.
Introduction: Otitis media with effusion (OME) affects hearing, speech development, and quality of life (QoL) in children. The 'Blow, Breathe, Cough' (BBC) intervention promotes nasal, respiratory, and middle ear clearanc...
Using healthcare-affiliated apps to recruit typically underrepresented populations in a pregnancy cohort study in West Virginia [0.03%]
利用医疗应用招募西弗吉尼亚州孕期队列研究中通常代表性不足的群体
Katrina L Wilhite,Elly Marshall,Carly Williamson Rogers et al.
Katrina L Wilhite et al.
Background: Individuals residing in rural areas and those with low socioeconomic status are typically underrepresented in clinical research. Strategies to recruit more representative populations should be explored. This s...
Ahrim Youn,Yue Yang
Ahrim Youn
In recent drug development, Phases 2 and 3 are increasingly combined into a seamless Phase 2/3 design to accelerate the drug development process. One of the seamless designs, known as the 2-in-1 adaptive design, allows a Phase 2 trial to ex...
The effects of transcranial direct current stimulation and fluency shaping techniques on enhancing speech fluency in adults who stutter: Protocol for a double-blind randomized controlled trial [0.03%]
经颅直流电刺激和流畅度塑造技术对提高成人结巴说话流畅度的影响：双盲随机对照试验方案
Kowsar Esfandeh,Ahmad Reza Khatoonabadi,Hamid Karimi et al.
Kowsar Esfandeh et al.
Background: Stuttering is a condition that usually begins in childhood and may continue into adulthood. In this study, it is suggested that the combined approach of transcranial direct current stimulation (tDCS) with flue...
A social engagement technology-based randomized controlled trial for older adults: Outcomes and lessons learned [0.03%]
基于社交参与技术的老年人随机对照试验：结果与经验教训
George Mois,Elizabeth A Lydon,Margaret K Danilovich et al.
George Mois et al.
Background: Loneliness and social isolation can negatively impact health, wellbeing, and quality of life of older adults. While social engagement supports social health, typical age-related changes (e.g., living arrangeme...
Evaluation of the effect of acupuncture on weight loss in postpartum obese women: a study protocol for a randomized controlled trial [0.03%]
针刺减肥对产后肥胖女性效果评价研究方案：一项随机对照试验
Han Zhang,Xinyu Zhang,Yuejiao Wang et al.
Han Zhang et al.
Background: Pregnant women gain an average weight of 16.6 ± 4.8 kg during pregnancy, with weight retention of 4 kg at 6 months, 4 kg at 12 months, and 2.9 kg at 18 months postpartum. At 3, 6, 9 and 12 months after delive...