The THRIVE-CP trial - Targeted home-based training with real-time feedback to improve versatile movement behaviors and enhance outcomes in adolescents and young adults with Cerebral Palsy: Protocol for a randomized controlled trial [0.03%]
针对改善脑瘫青少年和年轻人多种运动行为的家庭基地训练与实时反馈的THRIVE-CP试验：随机对照试验方案
Ivana Bardino Novosel,Jan Christensen,Mikkel Damgaard Justiniano et al.
Ivana Bardino Novosel et al.
Protocol for the rural engagement in TelemedTeam for options in obesity treatment solutions (RE-TOOL): Cluster randomized trial investigating team-based telemedicine in rural primary care [0.03%]
TelemedTeam在农村社区初级保健中进行肥胖症治疗的集群随机试验(RE-TOOL)方案：基于团队的远程医疗服务农村参与计划
Alexandra R Brown,Edward F Ellerbeck,Debra K Sullivan et al.
Alexandra R Brown et al.
Rural communities experience disproportionately high rates of obesity and related chronic diseases. Rural residents report a lack of weight control programs within their communities, leaving primary care physicians (PCPs)at the center of ob...
Unmasking three blinding indices for randomized controlled trials: comparison and application [0.03%]
揭开三项随机对照试验盲法指标的面纱：比较与应用
Javier Muñoz Laguna,Jafar Kolahi,Heejung Bang
Javier Muñoz Laguna
Blinding is an important methodological aspect of randomized controlled trials. Although three blinding indices are available for the estimation of blinding in clinical trials, little guidance is available regarding their comparison and app...
Efficacy and safety of Chinese medicine compound for the convalescent COVID-19 patients: Protocol of a multi-centered, randomized, double-blinded, placebo-controlled clinical trial [0.03%]
新冠恢复期患者中医复方疗效和安全性的评价：多中心随机双盲安慰剂对照临床试验方案
Rui Fang,Wanyao Yang,Yue Zhou et al.
Rui Fang et al.
Background: Convalescent coronavirus disease 2019 (COVID-19) refers to a series of clinical syndromes in patients with COVID-19 infection that follow the relevant discharge indications but do not fulfill the criteria for ...
RESCUER mobile app to support pediatric resuscitation: Study protocol for a randomized controlled trial [0.03%]
一种支持儿科复苏的手机应用（救援者）：一项随机对照试验的研究方案
Samantha A Lee,Diego Trujillo,Garth D Meckler et al.
Samantha A Lee et al.
Background: Pediatric out-of-hospital cardiac arrest is a leading cause of death in children. This paper describes the study protocol for the randomized control trial to test a linear cognitive aid app (RESCUER) designed ...
Wellbeing for staff in UKCRC-registered Clinical Trials Units: Development of the Flourishing As Clinical Trial Staff (FACTS) guidance: a mixed-methods study [0.03%]
英国临床试验单位（UKCRC注册）工作人员的幸福感：繁荣作为临床试验工作人员（FACTS）指南的制定：一种混合方法研究
Sophie S Hall,Evgenia Riga,Eleanor J Mitchell et al.
Sophie S Hall et al.
Background: Evaluating healthcare interventions in clinical trials requires a skilled workforce. However, the demands of developing and running clinical trials make recruiting and retaining staff challenging. Flourishing,...
Establishing a clinical trial site: A primer for aspiring principal investigators [0.03%]
临床试验现场的建立——面向有志于成为主要研究者的指南
John J Sramek,Modesto S Carrillo,Neal R Cutler
John J Sramek
Establishing a private clinical trial site is an increasingly appealing but complex opportunity for physicians interested in becoming Principal Investigators (PIs) in FDA-regulated research. This article provides a comprehensive overview fo...
Rationale and protocol for a prospective clinical trial enrollment improvement hybrid study within a trial [0.03%]
前瞻性临床试验入组改善混合研究的 rationale 和方案
Patrick Lewicki,Sabrina Clark,Elaina Shoemaker et al.
Patrick Lewicki et al.
Introduction: Enrollment to clinical trials is challenging, and few evidence-based interventions to improve enrollment exist. Provider-facing advertising campaigns could help increase enrollment, but this type of interven...
Randomized trial of multi-strain Lactobacillus crispatus vaginal live biotherapeutic products after antibiotic therapy for bacterial vaginosis: study protocol for VIBRANT (vaginal lIve biotherapeutic RANdomized trial) [0.03%]
一项在细菌性阴道病抗生素治疗后使用多株乳酸菌(Lactobacillus crispatus)活体生物治疗产品的随机对照试验：VIBRANT(阴道活体生物制剂随机对照试验)研究方案
Callin Chetty,Nomfuneko Mafunda,Anna-Ursula Happel et al.
Callin Chetty et al.
Background: Globally, approximately 30 % of women have bacterial vaginosis (BV). Antibiotic treatment is frequently followed by recurrence, likely due to lack of colonization with beneficial lactobacilli. ...
Efficacy of an integrated treatment for fathers with Co-occurring substance misuse and family violence [0.03%]
联合治疗对同时患有物质滥用和家庭暴力的父亲的效果研究
Carla S Stover,Sarah Meshberg-Cohen,Galina A Portnoy et al.
Carla S Stover et al.
Substance Use (SU) and Family Violence (FV) are both critical public health concerns and often occur together. However, most existing interventions target only one of these problems, without consideration of the other, and fail to address w...