Study design and protocol for a randomized clinical trial investigating a brief fear of uncertainty-focused intervention as an adjunct to project safe guard for military personnel [0.03%]
调查项目安全护盾的辅助干预措施（针对军事人员不确定性的恐惧）的研究设计与方案研究(randomized clinical trial)
Samantha E Daruwala,Kayley Stratton,Grace Y Cho et al.
Samantha E Daruwala et al.
Background: In the United States (US), the proportion of firearm suicide deaths are higher among military personnel compared to the general population. Secure firearm storage practices (e.g., gun safe, unloaded) can reduc...
The effect of combined rhythmic breathing and aromatherapy on pain intensity and anxiety in patients with unstable angina [0.03%]
节奏性呼吸与芳香疗法结合对不稳定性心绞痛患者疼痛强度和焦虑感的影响研究
Sahar Nouri,Nasrin Hanifi,Farhad Ramezani-Badr
Sahar Nouri
Background: Unstable angina is a serious heart condition characterized by intense chest pain and anxiety, which substantially reduces patients' well-being. ...
What works for men? Participant perspectives from a mixed-gender weight-management trial with incentives [0.03%]
什么对男性有效？带有奖励的混合性别体重管理试验参与者视角
Katya Garza,Hisham Ahmad,Bhabna Pati et al.
Katya Garza et al.
Background: Men are underrepresented in behavioral weight-loss trials, limiting the generalizability of findings. While gender-tailored programs have shown success, most research and community-based weight management prog...
Designing trials with multiple objectives with graphical approach for multiple scenarios [0.03%]
用于多种情形的多目标试验设计的图形方法
A Adam Ding,Yulin Li,Samuel S Wu
A Adam Ding
Clinical trials with multiple objectives require careful control of the overall error rate through adjustments for multiple hypothesis testing. Design optimization must account for these adjustments across various plausible scenarios. This ...
Representation and career trajectories of female principal investigators in clinical trials, 2010-2023 [0.03%]
2010年至2023年临床试验中女性首席调查员的代表性及其职业发展轨迹
Manuel Hermosilla
Manuel Hermosilla
Background: Gender disparities persist in clinical trial leadership, with women underrepresented as principal investigators (PIs). While previous studies have documented these disparities, they have largely relied on limi...
Time-restricted eating in Alzheimer's disease: TREAD pilot trial design [0.03%]
阿尔茨海默病的时间限制性饮食干预：TREAD试验设计
Susan B Racette,Jordan A Gunning,Danielle E Eagan et al.
Susan B Racette et al.
Background and objective: Time-restricted eating (TRE) may slow neurodegeneration and cognitive decline by stimulating metabolic processes that are neuroprotective. The primary aim of the TRE in Alzheimer's Disease (TREAD...
A randomized clinical trial of surgical intervention with or without acupuncture combined with traditional Chinese medicine to treat intrauterine adhesions [0.03%]
宫腔粘连术后应用针药结合治疗的随机对照临床试验研究项目
Zhao Wenwen,Wang Jiaqi,Sun Jing et al.
Zhao Wenwen et al.
Purpose: To evaluate traditional Chinese medicine (TCM) and acupuncture in addition to estrogen/progesterone therapy in the post-operative management of intrauterine adhesions. ...
The culturally adapted cognitive behavioral stress management program for enhancing psychological well-being and self-management of postoperative breast cancer patients: A randomized controlled study protocol in China [0.03%]
针对乳腺癌术后患者心理健康的改良认知行为压力管理方案的增强及自我管理的随机对照试验方案在中国的实施效果研究
Linzhi Jiang,Rongrong Liu,Xingqun Tan et al.
Linzhi Jiang et al.
Introduction: Breast cancer patients often face mental health challenges after prolonged treatment. High incidence and mortality rates, coupled with a shortage of healthcare professionals and heavy clinical workloads, fre...
A protocol for management of presbyopia through ancient yogic eye purificatory method: A randomized controlled trial [0.03%]
一项通过古代瑜伽净眼光学方法管理老花眼的方案：随机对照试验
Lavya Shetty,Yogish Subraya Kamath,Annapoorna K et al.
Lavya Shetty et al.
Presbyopia is an age-related eye condition observed in older people (who are above 40 years), whereby there is a gradual loss of the ability to focus on near items. Some common symptoms include seeing near as blurred, eye strain, and a head...
Evaluating the impact of delayed study startup on accrual in cancer studies [0.03%]
延迟启动对癌症研究入组的影响评估
Isuru Ratnayake,Anh-Tuan Do,Daniel Gajewski et al.
Isuru Ratnayake et al.
Background: Drug development in cancer medicine relies on high-quality clinical trials, and the success of these trials depends on the design, optimization, and execution. Delays often arise from the study startup process...