Enhancing behavioral treatment for women with pelvic floor disorders: Study protocol for a pilot randomized controlled trial [0.03%]
盆底功能障碍行为治疗增强方案:一项初步随机对照试验的研究方案
Bayley J Taple,James W Griffith,Claire Weaver et al.
Bayley J Taple et al.
Approximately one in four American women report bothersome urinary symptoms (e.g., urgency, frequency), which greatly impact quality of life, including mental health. Bidirectional relationships have been found between urinary symptoms and ...
Embedded Motivational Interviewing combined with a smartphone app to increase physical activity in people with sub-acute low back pain: Study protocol of a cluster randomised control trial [0.03%]
结合手机应用程序嵌入式动机访谈以增加亚急性腰背痛患者的体力活动:集群随机对照试验的研究方案
Paul D O Halloran,Jason Holden,Jeff Breckon et al.
Paul D O Halloran et al.
Background: Motivational Interviewing is an evidence-based, client-centred counselling technique that has been used effectively to increase physical activity, including for people with low back pain. One barrier to implem...
Audience segmentation as a strategy for enhancing the use of research registries for recruiting patients into clinical trials [0.03%]
受众划分作为增强研究注册库在临床试验患者招募中的使用策略的一项研究
Elizabeth Flood-Grady,Jiawei Liu,Samantha R Paige et al.
Elizabeth Flood-Grady et al.
Introduction: Health research registries have great potential to increase awareness of research opportunities among diverse patient populations and reduce disparities in clinical trial accrual. However, little research ha...
Efficient dose-finding for drug combination studies involving a shift in study populations [0.03%]
涉及研究人群变化的药物组合剂量寻找的有效方法
Nolan A Wages,Trish A Millard,Patrick M Dillon et al.
Nolan A Wages et al.
This paper describes the design of an early phase, prospective trial evaluating the safety and tolerability of the combination of the histone deacetylase inhibitor, entinostat, in combination with capecitabine. The study consists of two par...
A multicenter randomized clinical trial to evaluate the efficacy of telemonitoring in patients with advanced heart and lung chronic failure. Study protocol for the ATLAN_TIC project [0.03%]
远程监控在外周动脉疾病和慢性肺病患者中的有效性的多中心随机临床试验方案(ATLAN TIC项目)
Carlos Hernandez-Quiles,Máximo Bernabeu-Wittel,Maria Del Rocio Garcia-Serrano et al.
Carlos Hernandez-Quiles et al.
Background: Using technologies of information and communication (TICs) is emerging in medical assistance. TICs application for medical assistance is promising. Its applicability in advanced heart and/or respiratory failur...
Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness [0.03%]
电话递送的激励措施鼓励服用美沙酮门诊病人坚持临床和成本效益研究的实施方案
Nicola Metrebian,Timothy Weaver,Stephen Pilling et al.
Nicola Metrebian et al.
The majority of people receiving treatment for their heroin addiction, are prescribed methadone; for which there is an extensive evidence base. When treatment starts, people take their daily dose of methadone under supervision at a communit...
The iReAct study - A biopsychosocial analysis of the individual response to physical activity [0.03%]
一项关于运动的生物心理社会学分析研究(iReAct研究)
Ansgar Thiel,Gorden Sudeck,Hannes Gropper et al.
Ansgar Thiel et al.
Background: Physical activity is a substantial promoter for health and well-being. Yet, while an increasing number of studies shows that the responsiveness to physical activity is highly individual, most studies focus thi...
Study design comparing written exposure therapy to cognitive processing therapy for PTSD among military service members: A noninferiority trial [0.03%]
军事人员书面暴露疗法与认知处理疗法对照研究:非劣效性试验
Denise M Sloan,Brian P Marx,Patricia A Resick et al.
Denise M Sloan et al.
Although there are a number of effective treatments for posttraumatic stress disorder (PTSD), there is a need to develop more efficient evidence-based PTSD treatments to address barriers to seeking and receiving treatment. Written exposure ...
Systematic review on the quality of randomized controlled trials in Saudi Arabia: Authors' response [0.03%]
沙特阿拉伯随机对照试验质量的系统评价:作者回应
Nazmus Saquib,Juliann Saquib,Ahmad Mamoun Rajab
Nazmus Saquib
Continued investigator engagement: Reasons principal investigators conduct multiple FDA-regulated drug trials [0.03%]
持续的研究者参与度:首席研究员开展多次FDA管理的药物试验的原因
Carrie B Dombeck,Terri Hinkley,Christopher B Fordyce et al.
Carrie B Dombeck et al.
Background/aims: Numerous reasons have been identified for why U.S.-based principal investigators choose to not continue participating in FDA-regulated trials. However, unexplored are reasons why a substantial number of p...