Causal association between gut microbiota composition and the risk of atrial fibrillation [0.03%]
肠道菌群与房颤的病因关系分析
Jiangshan Tan,Jingyang Wang,Yanmin Yang et al.
Jiangshan Tan et al.
Background and objectives: Considerable evidence has shown that alterations in gut microbiota composition are associated with atrial fibrillation (AF). However, the causal associations remain largely unresolved. This stud...
Harnessing the potential of small extracellular vesicle biomarkers for cancer diagnosis and prognosis with advanced analytical technologies [0.03%]
利用先进的分析技术挖掘小型细胞外囊泡生物标志物在癌症诊断和预后中的潜力
Claudia Wing Lam Tam,Judy Wai Ping Yam
Claudia Wing Lam Tam
Small extracellular vesicles (sEVs), also referred as exosomes, have emerged as valuable indicators of cancer progression and response to treatment. They offer prospective targets for therapeutic interventions as well as insightful informat...
Artificial intelligence-based predictive model for relapse in acute myeloid leukemia patients following haploidentical hematopoietic cell transplantation [0.03%]
基于人工智能的预测模型在单倍型造血细胞移植后急性髓系白血病患者复发中的应用
Shuang Fan,Haoyang Hong,Shengye Lu et al.
Shuang Fan et al.
Background and objectives: Relapse is one of the most critical causes of transplant failure in patients with acute myeloid leukemia (AML) receiving haploidentical-related donor (HID) hematopoietic stem cell transplantatio...
Mitochondrial quality control as a therapeutic target in cardiovascular disease: Mechanistic insights and future directions [0.03%]
心血管疾病中线粒体质量控制的治疗靶点：机制见解与未来方向
Miao Zhang,Tong Zhang,Rongjun Zou et al.
Miao Zhang et al.
Mitochondrial dysfunction is increasingly recognized as a critical driver in the pathogenesis of cardiovascular diseases. Mitochondrial quality control (MQC) is an ensemble of adaptive mechanisms aimed at maintaining mitochondrial integrity...
Current understanding and controversy on brain access of GLP-1 and GLP-1 receptor agonists [0.03%]
GLP-1及GLP-1受体激动剂入脑的现有认知与争议
Jianuo Feng,Tianru Jin
Jianuo Feng
For more than two decades, peripheral administration of GLP-1 or GLP-1 receptor (GLP-1R) agonist (GLP-1RA) curbs appetite and reduce body weight gain in animal models. More importantly, the body weight lowering effect has been effectively o...
CircPLK1 upregulates ETS1 to confer anthracycline resistance in triple-negative breast cancer [0.03%]
环状RNA CircPLK1通过上调ETS1介导三阴性乳腺癌耐药性
Danian Dai,Jinhui Zhang,Yunxian Mo et al.
Danian Dai et al.
Background and objectives: Circular RNAs play a vital role in developing triple-negative breast cancer (TNBC). Likewise, the function of circRNAs in TNBC resistance to chemotherapy remains largely unknown. Here, we aimed ...
N-acetylglucosaminyltransferase V attenuates myocardial infarction by mediating the insulin-like growth factor 1 receptor signaling pathway [0.03%]
N-乙酰葡萄糖胺转移酶V通过介导胰岛素样生长因子1受体信号通路缓解心肌梗死
Tianqi Chang,Yangya&#x;nan Jin,Chenyu Fan et al.
Tianqi Chang et al.
Background and objectives: N-glycosylation, a crucial post-translational modification, is well-recognized for its pivotal role in cardiovascular functions. N-acetylglucosaminyltransferase V (GnT-V) is one of the major gly...
Advances in the diagnosis and treatment of gastrointestinal tumors under the concept of super minimally invasive surgery [0.03%]
超级微创理念下的胃肠肿瘤诊疗进展
Qianqian Chen,Yaoqian Yuan,Enqiang Linghu
Qianqian Chen
A similar effect of fibrinogen on efficacy and safety of tenecteplase versus alteplase in acute ischemic cerebrovascular events (TRACE II) trial [0.03%]
纤维蛋白原对替奈普酶与阿替普酶在急性缺血性脑血管事件疗效和安全性影响的比较：TRACE II试验
Lamia M&#x;barek,Aoming Jin,Yuesong Pan et al.
Lamia M&#x;barek et al.
Background and objectives: Hemostasis factors affecting clot patterns, particularly fibrinogen, may influence the effectiveness of intravenous thrombolysis (IVT). We aimed to investigate the impact of differences in fibri...
Artificial intelligence in glycemic management for diabetes: Applications, opportunities and challenges [0.03%]
人工智能在糖尿病血糖管理中的应用、机遇与挑战
Zhen Ying,Xiaoying Li,Ying Chen
Zhen Ying