Oncogenic KRAS triggers metabolic reprogramming in pancreatic ductal adenocarcinoma [0.03%]
致癌KRAS触发胰腺导管腺癌中的代谢重编程
Xuqing Shen,Ningning Niu,Jing Xue
Xuqing Shen
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with an extremely high lethality rate. Oncogenic KRAS activation has been proven to be a key driver of PDAC initiation and progression. There is increasing evidence that PDAC ...
A pan-cancer analysis of the oncogenic role of Golgi transport 1B in human tumors [0.03%]
人类肿瘤中内质网运输1B癌基因作用的泛癌症分析
Bo Tian,Yanan Pang,Ye Gao et al.
Bo Tian et al.
Background: Owing to the aggressiveness and treatment-refractory nature of cancer, ideal candidates for early diagnosis and treatment are needed. Golgi transport 1B (GOLT1B) has been associated with cellular malignant beh...
Jindong Xie,Fengxi Ye,Xinpei Deng et al.
Jindong Xie et al.
Circular RNAs (circRNAs) are a class of single-stranded RNAs with covalently closed structures. Owing to their not having 3' or 5' ends, circRNAs are highly durable and insusceptible to exonuclease-mediated degradation. Moreover, some circR...
Global lineage evolution pattern of sars-cov-2 in Africa, America, Europe, and Asia: A comparative analysis of variant clusters and their relevance across continents [0.03%]
非洲、美洲、欧洲和亚洲的SARS-CoV-2全球谱系演化模式:变异群集及其跨大陆相关性的比较分析
June Hyug Choi,Mee Sook Jun,Jeong Yong Jeon et al.
June Hyug Choi et al.
Objective: The objective of this study is to provide a comparative analysis of variant clusters and their relevance across Africa, America, Europe, and Asia, in order to understand the evolutionary patterns of the virus a...
Xin Qiao,Yuxiao Ding,Abdullah Altawil et al.
Xin Qiao et al.
A generalized deep learning model for heart failure diagnosis using dynamic and static ultrasound [0.03%]
一种用于心力衰竭诊断的通用深度学习模型(使用动态和静态超声数据)
Zeye Liu,Yuan Huang,Hang Li et al.
Zeye Liu et al.
Objective: Echocardiography (ECG) is the most common method used to diagnose heart failure (HF). However, its accuracy relies on the experience of the operator. Additionally, the video format of the data makes it challeng...
A new ferroptosis-related signature model including messenger RNAs and long non-coding RNAs predicts the prognosis of gastric cancer patients [0.03%]
一个包括信使RNA和长链非编码RNA的新型铁死亡相关特征模型可预测胃癌患者的预后
Yang Liu,Yanqing Liu,Shujun Ye et al.
Yang Liu et al.
Background and objectives: Gastric cancer (GC) is among the most malignant tumor types, which causes heavy healthy and economic burden to the people and societies all around the world. Establishment of an effective set of...
Long-term outcomes of esophageal and gastric cancer patients with cardiovascular and metabolic diseases: A two-center propensity score-matched cohort study [0.03%]
心血管及代谢性疾病食管癌和胃癌患者长期结局:一项来自2家中心的倾向性匹配队列研究
Bo Zhou,Zhixin Wang,Qifeng Dou et al.
Bo Zhou et al.
Background and objectives: An increased risk of cardiovascular and metabolic diseases (CVMDs) among patients with cancer suggests a potential link between CVMD and cancer. The impact of CVMD on the survival time of patien...
Total and individual PBC-40 scores are reliable for the assessment of health-related quality of life in Greek patients with primary biliary cholangitis [0.03%]
PBC-40总分和各项评分在希腊原发性胆汁性胆管炎患者健康相关生活质量评估中的可靠性较好
Eirini I Rigopoulou,Marianna Bakarozi,Ioannis Dimas et al.
Eirini I Rigopoulou et al.
Background: Primary biliary cholangitis (PBC) has been long associated with impairment of various aspects of health-related quality of life (HRQoL) with substantial differences among populations. This study evaluated for ...
Endoscopic diagnosis and treatment of superficial non-ampullary duodenal epithelial tumors: A review [0.03%]
内镜下非壶腹部十二指肠上皮肿瘤的诊断与治疗进展:综述
Zheng Zhao,Yue Jiao,Shuyue Yang et al.
Zheng Zhao et al.
The surface of the small bowel mucosa is covered more than any other section of the digestive canal; however, the overall prevalence of small bowel tumors of the whole gastrointestinal tract is evidently low. Owing to the improvement in end...