The role of TIM3+ NK and TIM3- NK cells in the immune pathogenesis of severe aplastic anemia [0.03%]
TIM3+NK和TIM3-NK细胞在重型再生障碍性贫血免疫发病机制中的作用
Shaoxue Ding,Tian Zhang,Yingying Lei et al.
Shaoxue Ding et al.
Background: Natural killer (NK) cells play important immunoregulatory roles in the immune pathogenesis of severe aplastic anemia (SAA). Our previous research showed that SAA caused a decrease in T cell immunoglobulin muci...
Factors associated with the delay in informed consent procedures of patients with ST-segment elevation myocardial infarction and its influence on door-to-balloon time: a nationwide retrospective cohort study [0.03%]
STEMI患者知情同意延迟的相关因素及其对门球时间影响的全国性回顾队列研究
Mailikezhati Maimaitiming,Junxiong Ma,Xuejie Dong et al.
Mailikezhati Maimaitiming et al.
Background and objectives: ST-segment elevation myocardial infarction (STEMI) is the deadliest and most time-sensitive acute cardiac event. However, failure to achieve timely informed consent is an important contributor t...
N6-methylation in the development, diagnosis, and treatment of gastric cancer [0.03%]
N6-甲基化在胃癌的发生、诊断和治疗中的作用
Jiaxin Wang,Guiping Zhao,Yan Zhao et al.
Jiaxin Wang et al.
Gastric cancer (GC) ranks third among cancers in terms of mortality rate worldwide. A clear understanding of the mechanisms underlying the genesis and progression of GC will contribute to clinical decision making. N6-methyladenosine (m6A) i...
Successful management of a high-risk acute myeloid leukemia patient with severe coronary heart disease by venetoclax plus azacytidine and coronary artery bypass grafting [0.03%]
维奈托克联合阿扎胞苷和冠状动脉旁路移植术成功治疗一例伴严重冠心病的高危急性髓系白血病患者
Wen-Jing Yu,Ying Wu,Jian Liu et al.
Wen-Jing Yu et al.
Circulating exosome long non-coding RNAs are associated with atrial structural remodeling by increasing systemic inflammation in atrial fibrillation patients [0.03%]
循环exo-lncRNA通过增加系统性炎症促进房颤心房结构重构
Yue Yuan,Xuejie Han,Xinbo Zhao et al.
Yue Yuan et al.
Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia with severe clinical sequelae, but its genetic characteristic implicated in pathogenesis has not been completely clarified. Accumulating evidence ...
Ferroptosis in organ fibrosis: From mechanisms to therapeutic medicines [0.03%]
器官纤维化中的铁依赖性细胞死亡:从机制到药物治疗
Weijing Lai,Bo Wang,Rongshuang Huang et al.
Weijing Lai et al.
Fibrosis occurs in many organs, and its sustained progress can lead to organ destruction and malfunction. Although numerous studies on organ fibrosis have been carried out, its underlying mechanism is largely unknown, and no ideal treatment...
Mucus hypersecretion in chronic obstructive pulmonary disease: From molecular mechanisms to treatment [0.03%]
慢性阻塞性肺疾病中的黏液高分泌:从分子机制到治疗
Ruonan Yang,Xiaojie Wu,Abdelilah Soussi Gounni et al.
Ruonan Yang et al.
Mitochondrial damage-associated molecular patterns in chronic obstructive pulmonary disease: Pathogenetic mechanism and therapeutic target [0.03%]
慢性阻塞性肺疾病中的线粒体损伤相关分子模式:病理机制和治疗靶点
Yongchun Shen,Lei Chen,Jun Chen et al.
Yongchun Shen et al.
Chronic obstructive pulmonary disease (COPD) is a common inflammatory airway disease characterized by enhanced inflammation. Recent studies suggest that mitochondrial damage-associated molecular patterns (DAMPs) may play an important role i...
Exosomes and their derivatives as biomarkers and therapeutic delivery agents for cardiovascular diseases: Situations and challenges [0.03%]
外泌体及其衍生物作为心血管疾病的生物标志物和治疗药物递送工具:现状与挑战
Yunyang Xu,Weimin Wan,Huixuan Zeng et al.
Yunyang Xu et al.
Microvesicles known as exosomes have a diameter of 40 to 160 nm and are derived from small endosomal membranes. Exosomes have attracted increasing attention over the past ten years in part because they are functional vehicles that can deliv...
Prognostic value of serum ammonia in critical patients with non-hepatic disease: A prospective, observational, multicenter study [0.03%]
非肝病重症患者血氨的预后价值:一项前瞻性、观察性、多中心研究
Yue Li,Zhipeng Yao,Yunlong Li et al.
Yue Li et al.
Background and objectives: Non-hepatic hyperammonemia can damage the central nervous system (CNS), and possible prognostic factors are lacking. This study aimed to investigate the prognostic and risk factors for patients ...