Virtual reality-based training in patients with alzheimer's disease: A systematic review and meta-analysis [0.03%]
基于虚拟现实的阿尔茨海默病患者的训练：系统回顾和meta分析研究
Junjie Wang,Can Wu,Kedong Zhu et al.
Junjie Wang et al.
Background and objectives: Prior meta-analyses have suggested that training utilizing virtual reality (VR) serves as a secure and effective intervention for elderly individuals experiencing mild cognitive impairment (MCI)...
Tetanus, diphtheria and pertussis vaccination and risk for incident dementia among adults with down syndrome [0.03%]
唐氏综合症成人破伤风、白喉和百日咳疫苗接种与以后发生痴呆的风险有关吗
Kimberly Schiel,Joanne Salas,Anjani Urban et al.
Kimberly Schiel et al.
Background: Adult vaccination is inversely associated with incident Alzheimer's Disease and Related Dementias. Objectives: We determine...
Income, diet, and cognitive function: observational analyses and candidate metabolomic pathways identified by Mendelian randomization [0.03%]
收入、饮食和认知功能：基于观察性分析及孟德尔随机化的候选代谢组学路径研究
Xingguang Zhao,Weijian Wu,Qiaoxuan Zhang et al.
Xingguang Zhao et al.
Background: Household income has been shown to have impact on cognitive function, with dietary patterns and gut microbiota-related metabolic pathways potentially acting as mediating pathways. Our study integrates observat...
Associations of plasma biomarkers with age in the presenilin-1 E280A autosomal dominant Alzheimer's disease kindred [0.03%]
载脂蛋白Eε2和ε4等位基因与早老素-1 E280A突变的家族性阿尔茨海默病患者血浆生物标志物年龄变化的关系
Vincent Malotaux,Vivian Ku,Paula Ospina Lopera et al.
Vincent Malotaux et al.
Background: Autosomal-dominant Alzheimer's disease (ADAD) offers a model to define early biological changes in Alzheimer's disease due to its predictable age at symptom onset. Although ultrasensitive plasma assays are ava...
Amyloid pathology and modifiable risk factors in cognitive decline among cognitively unimpaired older adults [0.03%]
无认知障碍老年人中淀粉样蛋白病理与可改变的危险因素在认知衰退中的作用
Ying-Hsin Hsu,Chih-Kuang Liang,Ming-Yueh Chou et al.
Ying-Hsin Hsu et al.
Background: Alzheimer's disease (AD) pathology, particularly amyloid-β (Aβ) deposition, occurs years before clinical symptoms. Modifiable risk factors may influence cognitive trajectories during this preclinical stage, ...
Jinjing Fu,Anders Sköldunger,Angela Bradshaw et al.
Jinjing Fu et al.
Cost analyses of plasma p-tau217 versus p-tau217/Aβ42 ratio using two-step approach in the Japanese health care system [0.03%]
日本医疗体系中采用两步法对血浆p tau217与p tau217/Aβ42比率的 cost analyses 分析
Masanori Kurihara,Ryoko Ihara,Kenichiro Sato et al.
Masanori Kurihara et al.
Plasma p-tau217 may offer a cost-saving effect in diagnosing Alzheimer's disease. However, each healthcare system has different costs, and its impact on evaluating anti-amyloid β (Aβ) therapies in Japan remains unclear. We conducted cost ...
The association between omega-3 supplementation and cognitive decline in older adults [0.03%]
Omega-3补充与老年人认知下降的关系分析
Zheng-Bin Liao,Zi-Cheng Hu,Gui-Hua Zeng et al.
Zheng-Bin Liao et al.
Background: While omega-3 fatty acid supplementation is widely used for cognitive protection, its efficacy remains controversial, and its impact on core Alzheimer's disease (AD) pathologies in humans is not well-establish...