Evaluating evidence-based recruitment strategies for Alzheimer's disease and related dementias clinical trial research: A literature review [0.03%]
基于证据的阿尔茨海默病及相关痴呆症临床试验研究招募策略的文献回顾及评估
Mireille Jacobson,Christina Deuschle,Desi Peneva et al.
Mireille Jacobson et al.
Background: With the prevalence of Alzheimer's disease and related dementias (ADRD) rising, prevention and treatment clinical trials are increasingly important. Yet inadequate participant recruitment to ADRD research-a le...
Discordance in amyloid positivity between visual reads and Centiloids: Impact of white matter uptake [0.03%]
视觉读数和Centiloid值之间淀粉样蛋白阳性不一致：脑白质摄取的影响
Arnaud Charil,Todd M Nelson,Anthonin Reilhac et al.
Arnaud Charil et al.
Background: The visual interpretation of amyloid PET scans, or visual read (VR), is the most common technique used in clinical practice to identify the presence of cerebral amyloid plaques. Amyloid status (positive or neg...
Corrigendum to "Lecanemab for treatment of individuals with early Alzheimer's Disease (AD) who are apolipoprotein E ε4 (ApoE ε4) non-carriers or heterozygotes" [The Journal of Prevention of Alzheimer's Disease (2026) 100507] [0.03%]
关于“莱卡内马布对载脂蛋白E ε4非携带者或杂合子的早期阿尔茨海默病患者的治疗”[《阿尔茨海默病预防杂志》(2026) 100507] 的勘误表
Richard Perry,Christopher Kipps,Maria Eugenia Soto Martín et al.
Richard Perry et al.
Amyloid spatial extent with florbetapir-PET for early detection of preclinical Alzheimer's disease [0.03%]
用于临床前阿尔茨海默病早期检测的florbetapir-PET淀粉样斑块空间范围研究
Emma G Thibault,Grace Del Carmen Montenegro,J Alex Becker et al.
Emma G Thibault et al.
Background: Prevention of Alzheimer's disease (AD) requires biomarkers sensitive to the earliest amyloid-β (Aβ) deposits. Objectives: ...
Living arrangements and cognitive resilience in aging: unraveling distinct pathways through plasma biomarkers [0.03%]
基于血浆生物标志物的老年人认知储备与居住安排的关系研究
Yuanyuan Peng,Heqianxi Dong,Yu Luo et al.
Yuanyuan Peng et al.
Background: Global aging and changing family structures necessitate identifying modifiable factors for cognitive health. While social isolation is a known risk, the protective role of specific living arrangements and thei...
Validation of a novel cognitive-functional outcome measure optimized for early Alzheimer's Disease: Evidence from the VIVA-MIND trial [0.03%]
阿尔茨海默病治疗的血管干预试验（VIVA-MIND）验证了一种新型认知功能结局测量指标：用于早期阿尔茨海默病的有效性证据
Jasmin A Duehring,Diane M Jacobs,David P Salmon et al.
Jasmin A Duehring et al.
Background: Cognitive-functional composite measures are increasingly used as primary efficacy endpoints in early Alzheimer's disease (AD) trials, where greater sensitivity to decline can improve trial efficiency and reduc...
Vincenzo Solfrizzi,Bruno P Imbimbo
Vincenzo Solfrizzi
Predicting cognitive decline: Comparative analysis of ANU-ADRI, CAIDE, CogDrisk, LIBRA, LIBRA2, UKBDRS and Lancet based dementia risk scores in the HUNT study [0.03%]
预测认知功能下降：ANU-ADRI、CAIDE、CogDrisk、LIBRA、LIBRA2、UKBDRS和Lancet基于痴呆症风险评分在HUNT研究中的比较分析
Josephine Stubs,Geir Selbæk,Bjørn Heine Strand et al.
Josephine Stubs et al.
Objective: To evaluate and compare the predictive value of eight dementia risk scores for late-life cognitive function and cognitive decline; ANU-ADRI, CAIDE, CogDrisk, LIBRA, LIBRA2, UKBDRS(-APOE), and a Lancet commissio...
Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis [0.03%]
营养补充剂与健康老龄化和轻度认知障碍患者认知之间的关系：系统评价和网络meta分析
Xing Liu,Chenyi Yang,Xinyi Wang et al.
Xing Liu et al.
Background: Nutritional supplementation is increasingly regarded as a potential strategy to preserve or enhance cognitive function in individuals with healthy aging and mild cognitive impairment (MCI). However, its overal...