Identification of a CD44-dependent control of astrocytic autophagic activity in Alzheimer's disease [0.03%]
阿尔茨海默病中CD44依赖的星形胶质细胞自噬活性调控的鉴定
Haiyan Wang,Ying Long,Yu Tang et al.
Haiyan Wang et al.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory impairment. Despite extensive research, the precise molecular mechanisms driving AD pathogenes...
Reductions in neuropsychiatric symptoms after lecanemab treatment and their associations with imaging markers of β-amyloid clearance [0.03%]
莱卡奈马b治疗后神经精神症状的减轻及其与β淀粉样蛋白清除影像标志物的相关性
Yaping Yan,Daoyan Hu,Linlin Kong et al.
Yaping Yan et al.
Background: Anti-amyloid-β (Aβ) therapies can slow cognitive decline and reduce cerebral amyloid burden in Alzheimer's disease (AD). Neuropsychiatric symptoms (NPS) are highly prevalent across the disease course and sub...
Effect of accelerometer-measured physical activity on the association between atrial fibrillation and risk of dementia [0.03%]
加速度计测量的体力活动对心房颤动和痴呆风险之间关联的影响
Le Li,Mengtong Xu,Lingmin Wu et al.
Le Li et al.
Background: Atrial fibrillation (AF) independently increases dementia risk, but whether accelerometer-measured physical activity (PA) modifies this association remains unquantified, particularly against self-reported PA l...
Clinical and biological relevance of objectively-defined subtle cognitive decline in Alzheimer's disease: a narrative review of neuroimaging, biomarker, and clinical progression studies [0.03%]
阿尔茨海默病客观定义的细微认知下降的临床和生物学意义：神经影像、生物标志物和疾病进程研究的叙述性回顾
Amanda I Gonzalez,Jairo E Martinez,Averi Giudicessi et al.
Amanda I Gonzalez et al.
Preclinical Alzheimer's Disease stages represent possible targets for disease-modifying intervention as well as opportunity for early identification of risk for future decline. Recent research has explored the use of objectively-defined sub...
Biomarkers in preclinical and early Alzheimer's disease in China: a scoping review [0.03%]
中国阿尔茨海默病临床前期和早期阶段生物标志物的研究：系统综述
Guoping Peng,Yan Yang,Ying Wang et al.
Guoping Peng et al.
This scoping review synthesizes evidence on fluid and neuroimaging biomarkers for preclinical and early Alzheimer's disease (AD)-including mild cognitive impairment (MCI) and mild AD dementia-in Chinese populations, where a comprehensive ov...
Class-level aggregation obscures clinically relevant heterogeneity in anti-amyloid antibody trials: comments on a Cochrane review by individual members of the EADC [0.03%]
针对Cochrane评论，EADC个体成员关于抗体试验中类水平汇总掩盖了临床相关异质性的评论文章
Kristian Steen Frederiksen,Mercè Boada,Lutz Frölich et al.
Kristian Steen Frederiksen et al.
Neuropsychiatric symptoms and dementia development: a 15-year population-based study [0.03%]
神经精神症状与痴呆发生发展关系的纵向队列研究(来自15年的社区人群队列)
Francesca Remelli,Giulia Grande,Serhiy Dekhtyar et al.
Francesca Remelli et al.
Background: Mild Behavioral Impairment (MBI) has been proposed to detect neuropsychiatric symptoms (NPS) associated with dementia development, but evidence from population-based settings is limited. ...
Depressive symptoms as a risk factor or prodrome of dementia: multi-state cognitive transitions modified by age and polygenic risk [0.03%]
抑郁症状作为痴呆的风险因素或前驱征兆：多状态认知转换受年龄和多基因风险影响模型
Ziyang Ren,Ruyi Zhang,Shuai Guo et al.
Ziyang Ren et al.
Background: Whether depressive symptoms signal a risk factor or a prodromal symptom of dementia, and how this depends on age, genetic susceptibility, and cognitive stages, remains controversial. ...
Corrigendum to "Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer's disease: evidence from multi-cohort analysis" [J Prev Alzheimer Dis, 13 (2026) 100422] [0.03%]
“系统性的蛋白质翻译后修饰基因组学鉴定出适用于阿尔茨海默病的治疗靶点：来自多队列研究证据”的勘误声明[JPAD，13 (2026) 100422]
Xiaoming Wang,Yuancheng Liu,Juncai Fu et al.
Xiaoming Wang et al.