ORM2 protects against acute pancreatitis by inhibiting premature activation of pancreatic enzymes [0.03%]
ORM2通过抑制胰酶过早活化保护急性胰腺炎
Bangwei Huang,Zijian Si,Xin Tan et al.
Bangwei Huang et al.
Background: Acute pancreatitis (AP) is characterized by dysregulated pancreatic enzyme activation and pancreatic tissue injury. Orosomucoid (ORM), an acute-phase protein with immunomodulatory functions, exhibits organ-spe...
When should I repeat the endoscopy in my patient with compensated cirrhosis, whom I just scoped and who had no or small varices? [0.03%]
代偿期肝硬化且食管静脉曲张不明显或较小的患者应何时进行胃镜复查？
Joanne C Imperial,Michael P McRae,Gregory T Everson
Joanne C Imperial
Endoscopic surveillance for patients with compensated advanced chronic liver disease (cACLD) is currently guided by the presence or size of esophageal varices. Current guidelines recommend repeat endoscopy every 2-3 years for patients with ...
Integration of local and systemic immunotherapy: setting new standards in liver-confined hepatocellular carcinoma [0.03%]
局部与全身免疫治疗的联合应用或重新定义肝细胞癌的标准疗法
Pei-Chang Lee,Yi-Hsiang Huang,David James Pinato
Pei-Chang Lee
Binding and transport functions of human serum albumin and its clinical implications in liver disease: a narrative review [0.03%]
人血清白蛋白的结合和转运功能及其在肝病中的临床意义：综述
Ran Tao,Chen Ding,Fei Wang et al.
Ran Tao et al.
Background and objective: Human serum albumin (HSA), a multifunctional plasma protein derived from the liver, plays a crucial role in the pathophysiology and management of liver diseases. Increasing research reveals that ...
Clinical profiles and risk predictors of drug-induced liver injury from pirfenidone and nintedanib used to treat idiopathic pulmonary fibrosis: a real-world analysis of a tertiary Chinese hospital cohort combined with FAERS data mining [0.03%]
吡非尼酮和尼达尼布治疗特发性肺纤维化所致药物性肝损伤的临床特征及风险预测因子：来自中国三级医院队列与FAERS数据挖掘的真实世界分析
Xinyi Ou,Yaozhou Wu,Qian Cheng et al.
Xinyi Ou et al.
Background: Drug-induced liver injury (DILI) is a known significant adverse effect of pirfenidone and nintedanib, essential antifibrotic agents for idiopathic pulmonary fibrosis (IPF). However, real-world evidence on the ...
Hepatic steatosis and fibrosis are associated with metabolic factors rather than endocrine therapy in breast cancer patients [0.03%]
乳腺癌患者的肝脂肪变性和纤维化与代谢因素的关系比内分泌治疗更为密切
Mateus Jorge Nardelli,Mísia Joyner de Sousa Dias Monteiro,Guilherme Grossi Lopes Cançado et al.
Mateus Jorge Nardelli et al.
Background: Steatotic liver disease (SLD) is prevalent among women with breast cancer, but the influence of hormonotherapy on its severity and progression remains uncertain. This study evaluated the prevalence, severity, ...
Leptin-dependent fat accumulation triggers autophagy in metabolic dysfunction-associated steatohepatitis model [0.03%]
基于瘦素依赖性脂肪蓄积的非酒精性脂肪肝病小鼠模型中代谢紊乱诱导的肝自噬反应机制研究
Sophia C H Polte,Tomomitsu Matono,Kinya Okamoto et al.
Sophia C H Polte et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a metabolic syndrome characterized by increased fat storage in hepatocytes. In the hepatocytes, autophagy protects against cytotoxic stress a...
Durvalumab and bevacizumab plus transarterial chemoembolization in unresectable hepatocellular carcinoma: a new paradigm? [0.03%]
德瓦鲁单抗和贝伐珠单抗联合经动脉化疗栓塞治疗不可切除肝细胞癌：新范式？
Maen Abdelrahim,Abdullah Esmail,Bandar Al-Judaibi
Maen Abdelrahim
Association between monocyte-to-lymphocyte ratio and metabolic dysfunction-associated steatotic liver disease and hepatic steatosis: evidence from NHANES 2017-2020 [0.03%]
2017-2020年NHANES数据中单核细胞/淋巴细胞比值与代谢异常相关性肝病和肝脏脂肪变性的关联分析
Yunyi Yang,Weijin Huang,Xiaoli He et al.
Yunyi Yang et al.
Background: The monocyte-to-lymphocyte ratio (MLR), an emerging inflammatory immune indicator, has an unclear association with metabolic dysfunction-associated steatotic liver disease (MASLD). This study aimed to evaluate...
A rare case report of hepatoblastoma in a child with ectopic adrenocorticotropic hormone syndrome [0.03%]
促肾上腺皮质激素异位综合征患儿并肝母细胞瘤1例报告
Shuang Gao,Zebin Xiao,Jing Yang et al.
Shuang Gao et al.
Background: Ectopic adrenocorticotropic hormone (ACTH) secretion is commonly associated with neuroendocrine tumors such as bronchial carcinoids. However, hepatoblastoma presenting with ectopic ACTH syndrome in children is...