Landscape of clinical trials and impact of precision medicine in biliary tract cancers in the last 45 years: a systematic review and meta-analysis of biomarker-driven trials [0.03%]
过去45年肝胆肿瘤临床试验格局和精准医学的影响：系统评价和基于生物标志物的临床试验 Meta 分析
Pedro Luiz Serrano Uson Junior,Fernando Moura,Frederico Monfardini et al.
Pedro Luiz Serrano Uson Junior et al.
Background: Biliary tract cancers (BTCs) collectively are challenging tumors despite some advances in research in the last years. Although multiple efforts, challenges in clinical trial recruitment and positive outcomes p...
Safely targeting combination TNF and IL-23 using a gut-restricted and orally delivered therapeutic approach: proof-of-concept for the development of SOR102 in ulcerative colitis [0.03%]
一种针对溃疡性结肠炎的口服肠道限制性药物SOR102的开发概念验证：同时靶向TNF和IL-23的安全组合疗法
Ilaria Faggiani,Remo Panaccione,Christopher Ma
Ilaria Faggiani
Development and validation of a nomogram for predicting postoperative survival in gallbladder cancer [0.03%]
胆囊癌术后生存预测的列线图的建立和验证
Yan-Yu Qiu,Qi Huang,Meng-Qing Sun et al.
Yan-Yu Qiu et al.
Background: Gallbladder cancer (GBC) exhibits significant heterogeneity in postoperative prognosis, and the traditional tumor-nodes-metastasis (TNM) staging system has limitations in individualized survival prediction. Th...
Emphysematous gastritis: a systematic review of reported cases exploring predictors of mortality [0.03%]
透行性胃炎的系统性病例分析及探讨预后因素
Mohammad Adam,Sameera Shuaibi,Mohamed Refaat et al.
Mohammad Adam et al.
Background: Emphysematous gastritis (EG) is a rare but life-threatening condition caused by gas-forming bacterial infection of the gastric wall. The rarity of this disease has resulted in limited consolidated data, making...
Effect of preoperative biliary drainage on peripheral circulating tumor cells after pancreaticoduodenectomy in patients with resectable periampullary carcinoma and obstructive jaundice [0.03%]
术前胆道引流对胰头癌可切除伴梗阻性黄疸患者术后外周循环肿瘤细胞的影响
Huajun Lin,Boyu Deng,Chenglin Xin et al.
Huajun Lin et al.
Background: Circulating tumor cells (CTCs) are pivotal in determining postoperative prognosis in periampullary carcinoma. However, the influence of preoperative biliary drainage (PBD) on CTC levels after pancreaticoduoden...
The impact of sedation on adenoma and polyp detection rates in colonoscopy: an evidence-informed narrative review [0.03%]
镇静对结肠镜检查腺瘤和息肉检出率影响的循证综述
Chuyu Xiao,Yuxin Chen,Jiayi Fan et al.
Chuyu Xiao et al.
Background and objective: Colorectal cancer (CRC) is one of the most prevalent cancers globally, with rising incidence and mortality rates. Early detection significantly improves survival, and colonoscopy is the gold stan...
CT-defined sarcopenia as a predictive factor in patients undergoing portal vein embolization: a systematic review and meta-analysis [0.03%]
基于CT定义的肌少症作为接受门静脉栓塞患者的预测因素：系统评价和荟萃分析
Hans-Jonas Meyer,Silke Zimmermann,Alexey Surov
Hans-Jonas Meyer
Background: Sarcopenia can be assessed by cross-sectional imaging and is a prognostic imaging marker in several diseases and tumor entities. First reports demonstrated a significant impact of the presence of sarcopenia on...
Koshiro Fukuda,Tsuyoshi Hamada,Tsuyoshi Takeda
Koshiro Fukuda
Cholecystectomy-induced gut dysbiosis and its consequences: bridging animal models and clinical outcomes in narrative review [0.03%]
胆囊切除诱发的肠道菌群紊乱及其后果：叙述性综述中的动物模型与临床结局之间的桥梁作用
Krerkrit Kijpongpans,Nipon Chattipakorn,Siriporn C Chattipakorn
Krerkrit Kijpongpans
Background and objective: Cholecystectomy is a commonly performed surgical procedure that alters bile acid storage and secretion, leading to continuous bile flow and disruption of the enterohepatic circulation. These alte...
Ectopic physiological portal vein reconstruction in liver transplantation for benign portal vein thrombosis [0.03%]
肝移植治疗良性门静脉血栓病的异位生理门静脉重建术
Jiyong Song,Guangdong Wu,Lihan Yu et al.
Jiyong Song et al.
Background: Benign portal vein thrombosis (PVT) presents considerable technical challenges for portal vein reconstruction (PVR) during liver transplantation (LT). This study aimed to evaluate the surgical outcomes, safety...