TET3-Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome [0.03%]
TET3介导的CCAT2 m5C修饰通过加速急性冠状动脉综合征中心肌微血管内皮细胞损伤促进疾病进展
Jun-Cheng Liu,Wen-Juan Wang,Ting-Ting Zhang et al.
Jun-Cheng Liu et al.
Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS-induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 i...
Refractory Lichen Amyloidosis Coexisting With Atopic Dermatitis Responsive to Sequential Janus Kinase Inhibitor Therapy: Upadacitinib Followed by Abrocitinib [0.03%]
伴发特应性皮炎的硬化型苔蘚淀粉样变病对雅美罗抑制剂治疗有反应：乌帕替尼继阿布昔替尼后的序贯疗法
Yu-Ting Tsai,Jui Lan,Shang-Hung Lin
Yu-Ting Tsai
Appendiceal Crohn's Disease Manifesting as Appendiceal Malignancy: A Case Report and Review of the Literature [0.03%]
阑尾克罗恩病误诊为阑尾恶性肿瘤一例及相关文献复习
Ming-Jung Meng,Tai-Di Chen,Puo-Hsien Le et al.
Ming-Jung Meng et al.
RTA-408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma [0.03%]
RTA-408通过JNK信号通路增强胶质母细胞瘤的放射敏感性及抑制肿瘤进展
Hung-Pei Tsai,Hao Qin,Yoon Bin Chong et al.
Hung-Pei Tsai et al.
Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA-408, a synthetic triterpenoid and nuclear factor erythroid 2-related factor 2 activator, exhibits anti-inflamm...
Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF-κB Signaling [0.03%]
鼠李素通过抑制TLR4/NF-κB信号减轻IgA肾病的肾脏损伤和肠上皮功能障碍
Meng-Si Li,Kai Liu
Meng-Si Li
IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose-deficient IgA1 (Gd-IgA...
Role of ZNF652 in Regulating Hepatocellular Carcinoma Cell Proliferation and Apoptosis via the circRHOT1/SLC38A6 Axis [0.03%]
ZNF652通过circRHOT1/SLC38A6轴调节肝癌细胞增殖和凋亡的作用机制研究
Kang Chen,Fei-Hu Sun,Chen Fan et al.
Kang Chen et al.
Hepatocellular carcinoma (HCC) is a heterogeneous malignancy characterized by high mortality rates. This article presents a discussion of the role of ZNF652 in HCC cell proliferation and apoptosis, thereby identifying a new target for HCC t...
Look Before You Cut: How a Killian-Jamieson Diverticulum Can Lead to Unnecessary Thyroidectomy [0.03%]
谨于甲状腺切除术前：Killian-Jamieson憩室导致不必要的甲状腺切除手术
Yi-Wei Sun,Tzu-Yen Huang,Che-Wei Wu
Yi-Wei Sun
USP54 Promotes Ferroptosis in Non-Small Cell Lung Cancer by Mediating FOXA2 Deubiquitination and Enhancing ACSL4 Transcription [0.03%]
USP54通过介导FOXA2去泛素化和增强ACSL4转录促进非小细胞肺癌铁死亡
Rui-Shi Wei,Yong-Ping Liu,Chun-Dong Gu et al.
Rui-Shi Wei et al.
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, with a 5-year survival rate of less than 20% and a high risk of recurrence despite advances in treatment. This study aimed to identify new therapeutic targets to inc...
Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21 [0.03%]
LCN2、sST2和FGF21作为儿童哮喘临床分型和病情预测的生物标志物潜力研究
Xu Yang,Hai Wang,Yong-Zheng Zhang et al.
Xu Yang et al.
Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers. Thi...
Hypoxia-Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β-Catenin Pathway [0.03%]
缺氧诱导的心肌细胞组蛋白乳酰化通过Wnt/β-catenin信号通路促进铁死亡发生
Xin-Hua Zhu,Jing-Wen Hou,Zhong-Ying Lv et al.
Xin-Hua Zhu et al.
This study investigated the effects of histone lactylation on ferroptosis in hypoxia-induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2-Deoxy-D-glucose (2-DG, a glucose analogue), ferrostatin-1 (Fer-1, a se...