Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer [0.03%]
Yuan Ma,Ying Li,Kai-Li Li
Yuan Ma
Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on...
Protective Effects of Riociguat Against Contrast-Induced Nephropathy: An Experimental and Machine Learning-Based Study in Rats [0.03%]
瑞戈非尼对对比剂肾病的保护作用：大鼠实验和机器学习研究
Mustafa Begenc Tascanov,Kenan Toprak,Sibel Turedi et al.
Mustafa Begenc Tascanov et al.
Contrast-induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventive strategies remain limited. This study investigated the renoprotective effects of riocig...
Construction of a Non-Invasive Predictive Model Based on PIVKA-II Combined With MRI Imaging Features for Evaluating Microvascular Invasion in Hepatocellular Carcinoma [0.03%]
基于PIVKA-II联合MRI影像特征构建非侵入性预测肝细胞癌微血管侵犯模型
Di Gao,Rui-Qi Jin,Hong-Wei Wang
Di Gao
This study developed a non-invasive model using PIVKA-II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study incl...
Emerging Deep Cutaneous Fungal Infection Caused by Cyphellophora Species in a Diabetic Patient [0.03%]
糖尿病患者由Cyphellopora属引起的新型皮肤深层真菌感染
Yi-Shan Teng,Pei-Lun Sun,Cheng-Che E Lan
Yi-Shan Teng
Triglyceride-Related Indices and Risk of Acute Pancreatitis: A Prospective Study in UK Biobank [0.03%]
血脂指标与急性胰腺炎风险的关系：英国生物银行前瞻性研究结果
Jing-Bo Li,Yu-Jiao Zhu,Yang-Jie Liao et al.
Jing-Bo Li et al.
Triglyceride-related indices, including triglyceride-glucose (TyG), TyG related to body mass index (TyG-BMI), TyG related to waist circumference (TyG-WC), TyG related to waist-to-height ratio (TyG-WHtR), atherogenic index of plasma (AIP), c...
Association Between Preoperative Dyslipidemia and the Prognosis of Patients With Endometrial Cancer: A Retrospective Cohort Study [0.03%]
术前血脂异常与子宫内膜癌患者预后关系的回顾性队列研究
Song Li,Rong-He Sun,Qing Chen et al.
Song Li et al.
Endometrial cancer (EC) is closely related to metabolic disorders. We aimed to investigate whether preoperative dyslipidemia independently affects the prognosis of patients with EC. One hundred and ninety-four women diagnosed with EC by pat...
Optimizing Voice Outcomes After Recurrent Laryngeal Nerve Transection: The Role of Early and Supplemental Injection Laryngoplast [0.03%]
喉返神经切断术后的嗓音优化：早期和补充性注射声带填充的作用
Luo-Wei Chan,Hsin-Yi Tseng,Che-Wei Wu et al.
Luo-Wei Chan et al.
LncRNA NORAD Enhances Inflammatory Injury in Sepsis-Associated Acute Lung Damage Through miR-150-5p/STAT1-Dependent NF-κB Activation [0.03%]
长链非编码RNA NORAD通过miR-150-5p/STAT1依赖的NF-κB活化促进脓毒症相关急性肺损伤中的炎症损伤
Han Liu,Xi-Xi Chen,Gui-Hua Wei et al.
Han Liu et al.
Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS-stimulated BEAS-2B and HBEC3-KT cells as well as cecal ligation and puncture (CLP)-induced ALI models in...
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities [0.03%]
致癌KRAS重塑应激颗粒动力学：机制与治疗机会
Msimisi Ndzinisa,Birhanetensay Masresha Altaye,Yuh-Pyng Sher
Msimisi Ndzinisa
Stress granules (SGs) are dynamic, membrane-less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and ...