RBMX Transcriptionally Repressed by EZH2-Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation [0.03%]
EZH2介导的RBMX表观遗传沉默通过调节SIRT3/NLRP3炎性小体途径抑制肾缺血再灌注损伤中pyroptosis发生
Yi-Han Wang,Yan Teng,Fang-Lan Yao et al.
Yi-Han Wang et al.
Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA-binding motif protein X-linked (RBMX), a modulator of m6A methylation, in renal I...
Persistent Pulmonary Atelectasis After Tracheoesophageal Fistula Repair: Diagnostic Challenge of a Communicating Bronchopulmonary Foregut Malformation Group 1a in a Neonate With VACTERL Association [0.03%]
气管食管瘘术后持续性肺不张：新生儿VACTERL关联征1型支气管肺前肠畸形综合征的诊断挑战
Tien-Pai Huang,Twei-Shiun Jaw,Yu-Tang Chang et al.
Tien-Pai Huang et al.
PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma [0.03%]
通过抑制ESM1转录调控PI3K / Akt信号轴促进铁死亡和增加索拉非尼敏感性并下调PRDM1的肾细胞癌研究
Yi-Shuai Zhang,Xin-Qi Pei,Ji-Ping Sun et al.
Yi-Shuai Zhang et al.
Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitini...
Proteomics-Based Identification of the Pyroptosis-Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis [0.03%]
基于蛋白质组学的焦亡相关生物标志物PCSK9的鉴定及其与类风湿性关节炎发病机制的关系
Lei Wang,Hao-Jie Chen,Ting-Ting Wu et al.
Lei Wang et al.
Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insigh...
Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway [0.03%]
伏隔核通过AMPK/SIRT1信号通路抑制铁死亡从而促进绝经后骨整合
Qing-Song Gu,Yi-Fan Gu,Jian-Qiao Li et al.
Qing-Song Gu et al.
The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone-forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA),...
Primary Retroperitoneal Mucinous Cystic Neoplasm Involving Adrenal Gland [0.03%]
累及肾上腺的一级腹膜后黏液性囊性神经内分泌肿瘤
Di-Ping Yu,Xiao-Long Liu,Xin-Yu Li
Di-Ping Yu
Combined Effects of Puerarin and Adipose-Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation [0.03%]
黄豆异黄酮与脂肪干细胞联合对牙周炎骨质保存及抗炎的效应及其对p38丝裂原活化蛋白激酶的影响
Ting Yang,Xu Zhang,Liang-Fu Zhang
Ting Yang
This study evaluated the effects of puerarin and adipose-derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were e...
Impact of Proton Pump Inhibitor Use on Outcomes Following Carotid Artery Stenting for Asymptomatic Carotid Stenosis: A Population-Based Cohort Study [0.03%]
质子泵抑制剂使用对无症状颈动脉狭窄患者行颈动脉支架置入术预后影响的队列研究
Chia-En Wong,Pang-Shuo Perng,Pei-Wen Chen et al.
Chia-En Wong et al.
Carotid artery stenting (CAS) is an effective treatment for carotid stenosis. Proton-pump inhibitors (PPIs) are commonly prescribed in the general population. However, the impact of PPI use on outcomes following CAS remains unknown. This st...
Reply to Comment on: "Impact of Depth of Invasion in Node-Negative Oral Tongue Cancer Treated With Surgery Alone" [0.03%]
有关“单用手术治疗淋巴结阴性的舌癌侵袭深度的影响”的评论的回复
Ming-Hsien Tsai,Hui-Ching Chuang,Chih-Yen Chien
Ming-Hsien Tsai
Extracellular Vesicle-Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis [0.03%]
前交叉韧带与骨髓细胞之间通过细胞外囊泡介导的通讯调节半膜肌腱细胞行为和凋亡
Hon-Lok Lo,Shih-Hao Huang,Ting-Hsuan Dai et al.
Hon-Lok Lo et al.
Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic poten...