Identification and Characterisation of Infiltrating Immune Cells in Malignant Pleural Mesothelioma Using Spatial Transcriptomics [0.03%]
空间转录组学在恶性胸膜间皮瘤浸润性免疫细胞的鉴定与表征中的应用
Dmitrii Shek,Brian Gloss,Joey Lai et al.
Dmitrii Shek et al.
Increasing evidence strongly supports the key role of the tumour microenvironment in response to systemic therapy, particularly immune checkpoint inhibitors (ICIs). The tumour microenvironment is a complex tapestry of immune cells, some of ...
Improvement and Validation of a Genomic DNA Extraction Method for Human Breastmilk [0.03%]
人乳基因组DNA提取方法的改进与验证
Mario Iván Alemán-Duarte,Blanca Rosa Aguilar-Uscanga,Guadalupe García-Robles et al.
Mario Iván Alemán-Duarte et al.
The human milk microbiota (HMM) of healthy women can vary substantially, as demonstrated by recent advances in DNA sequencing technology. However, the method used to extract genomic DNA (gDNA) from these samples may impact the observed vari...
Protocol to Assess the Biological Activity of Insulin Glargine, Insulin Lispro, and Insulin Aspart In Vitro [0.03%]
用于评估甘精胰岛素、赖脯胰岛素和天冬胰岛素体外生物活性的协议
Mamatha Garige,Susmita Ghosh,Brian Roelofs et al.
Mamatha Garige et al.
Insulin is a hormone produced by β-cells of the pancreas and controls the amount of sugar in the blood. Since its discovery over 100 years ago, insulin has been used as a life-saving treatment for people with diabetes. Historically, the bi...
An Experimental Approach to Address the Functional Relationship between Antioxidant Enzymes and Mitochondrial Respiratory Complexes [0.03%]
抗氧化酶和线粒体呼吸链复合物之间功能关系的实验研究
Daniela Mendes,Ana Maria Silva,Maria Manuel Oliveira et al.
Daniela Mendes et al.
Mitochondrial dysfunction and cytosolic oxidative stress are pathological biomarkers interlinked in several chronic diseases and cellular toxicity promoted by high-energy radiation or xenobiotics. Thus, assessing the activities of the mitoc...
An Efficient Method to Prepare Barcoded cDNA Libraries from Plant Callus for Long-Read Sequencing [0.03%]
高效制备植物愈伤组织条形码cDNA文库用于长读长测序方法
Daniela Cordeiro,Alexandra Camelo,Ana Carolina Pedrosa et al.
Daniela Cordeiro et al.
Long-read sequencing methods allow a comprehensive analysis of transcriptomes in identifying full-length transcripts. This revolutionary method represents a considerable breakthrough for non-model species since it allows enhanced gene annot...
Community Mobilization and Community Incentivization (CoMIC) Strategy for Child Health in a Rural Setting of Pakistan: Study Protocol for a Randomized Controlled Trial [0.03%]
巴基斯坦农村地区儿童健康社区动员和社区激励（CoMIC）策略研究：一项随机对照试验的研究方案
Jai K Das,Rehana A Salam,Arjumand Rizvi et al.
Jai K Das et al.
Despite the decline in under-five mortality by over 60% in the last three decades, majority of child mortality is still attributable to communicable and infectious diseases that are not only preventable, but they are also treatable. We eval...
Interventions to Increase Physical Activity in Community-Dwelling Older Adults in Regional and Rural Areas: A Realist Synthesis Review Protocol [0.03%]
促进区域和农村社区中老年人身体活动的干预措施：现实合成审查方案
Stephen Cousins,Rebecca McKechnie,Patricia Jackman et al.
Stephen Cousins et al.
The importance of physical activity (PA) for the health and wellbeing of older adults is well documented, yet many older adults are insufficiently active. This issue is more salient in regional and rural areas, where evidence of the most cr...
Patient-Reported Quality of Care for Osteoarthritis in General Practice in South Tyrol, Italy: Protocol for Translation, Validation and Assessment of the OsteoArthritis Quality Indicator Questionnaire (OA-QI) [0.03%]
意大利南蒂罗尔地区普通门诊患者关节炎治疗质量报告：OsteoArthritis 质量指标问卷(OA-QI)的翻译、验证及评估计划
Christian J Wiedermann,Pasqualina Marino,Antje van der Zee-Neuen et al.
Christian J Wiedermann et al.
Background: Evidence-based recommendations for the treatment of knee and hip osteoarthritis are similar internationally. Nevertheless, clinical practice varies across countries. Instruments for measuring quality have been...
Assessing the Effectiveness of Tobacco 21 Laws to Reduce Underage Access to Tobacco: Protocol for a Repeated Multi-Site Study [0.03%]
评估烟草销售法律对减少青少年获取烟草效果的研究：多点重复研究计划
Mary Hrywna,Amanda Y Kong,Christopher Ackerman et al.
Mary Hrywna et al.
Prior to the federal law passed in December 2019, many states passed an increased age of sale law prohibiting youth under age 21 (or Tobacco 21) from purchasing tobacco products, including e-cigarettes. Although previous research has docume...
Test-Retest Reliability of Isokinetic Ankle, Knee and Hip Strength in Physically Active Adults Using Biodex System 4 Pro [0.03%]
生物动力系统4型测试仪进行等速踝关节、膝关节和髋关节肌力的动力测试-复测信度研究
Juho Tuominen,Mari Leppänen,Heidi Jarske et al.
Juho Tuominen et al.
Background: The isokinetic dynamometry is considered a gold standard in muscle strength testing. The reliability of lower limb isokinetic strength measurements has not been thoroughly evaluated. ...