Modules for in vitro metabolic engineering: Pathway assembly for bio-based production of value-added chemicals [0.03%]
体外代谢工程模块：生物制造增值化学品的途径组装
Hironori Taniguchi,Kenji Okano,Kohsuke Honda
Hironori Taniguchi
Bio-based chemical production has drawn attention regarding the realization of a sustainable society. In vitro metabolic engineering is one of the methods used for the bio-based production of value-added chemicals. This method involves the ...
Heterologous expression of Avermectins biosynthetic gene cluster by construction of a Bacterial Artificial Chromosome library of the producers [0.03%]
avermectin 生物合成基因簇的异源表达及其产生菌BAC文库的构建
Qian Deng,Li Zhou,Meizhong Luo et al.
Qian Deng et al.
Avermectins, a group of polyketide natural products, are widely used as anthelmintics in agriculture. Metabolic engineering and combinatorial biosynthesis were extensively employed to improve Avermectins production and create novel Avermect...
Novel polysaccharide-protein conjugates provide an immunogenic 13-valent pneumococcal conjugate vaccine for S. pneumoniae [0.03%]
新型糖蛋白缀合物可提供有效的十三价肺炎球菌结合疫苗
Allison E B Turner,Jonas E Gerson,Helen Y So et al.
Allison E B Turner et al.
Pneumonia remains the single leading cause of childhood death worldwide. Despite the commercial availability of multiple pneumococcal conjugate vaccines (PCVs), high dosage cost and supply shortages prevent PCV delivery to much of the devel...
Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus [0.03%]
产生克拉维酸的工业菌株Streptomyces clavuligerus蛋白组的改变
Eser Ünsaldı,Aslıhan Kurt-Kızıldoğan,Birgit Voigt et al.
Eser Ünsaldı et al.
The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in s...
Evaluation of fermentation conditions triggering increased antibacterial activity from a near-shore marine intertidal environment-associated Streptomyces species [0.03%]
评价近岸潮间带相关链霉菌属菌株发酵条件以提高抗菌活性
A L English,A Boufridi,R J Quinn et al.
A L English et al.
A near-shore marine intertidal environment-associated Streptomyces isolate (USC-633) from the Sunshine Coast Region of Queensland, Australia, cultivated under a range of chemically defined and complex media to determine optimal parameters r...
Yuan Lu
Yuan Lu
Cell-free synthetic biology emerges as a powerful and flexible enabling technology that can engineer biological parts and systems for life science applications without using living cells. It provides simpler and faster engineering solutions...
Carmen Sánchez
Carmen Sánchez
Preventive medicine and food industry have shown an increased interest in the development of natural antioxidants, since those most commonly used synthetic antioxidants may have restricted use in food. This could explain why there is curren...
Development of fungal cell factories for the production of secondary metabolites: Linking genomics and metabolism [0.03%]
基于子囊菌细胞工厂的次级代谢产物生产研究：基因组与代谢之间的关联性分析
Jens Christian Nielsen,Jens Nielsen
Jens Christian Nielsen
The genomic era has revolutionized research on secondary metabolites and bioinformatics methods have in recent years revived the antibiotic discovery process after decades with only few new active molecules being identified. New computation...
Introduction to the Special Issue: "Arnold Demain - Industrial microbiologist extraodinaire" [0.03%]
阿纳尔德·戴梅因专刊序言：“产业微生物学家奇才”
Mattheos Koffas,Qiang Gao,Lixin Zhang
Mattheos Koffas