Oxyresveratrol reduces lipopolysaccharide-induced inflammation and oxidative stress through inactivation of MAPK and NF-κB signaling in brain endothelial cells [0.03%]
氧茋通过抑制MAPK和NF-κB信号通路减少脑内皮细胞LPS诱导的炎症及氧化应激反应
Yan Zhou,Qiaowen Deng,Chi Teng Vong et al.
Yan Zhou et al.
Inflammatory responses and oxidative stress damage the integrity of the blood-brain barrier (BBB), which is a primary pathological modulator of neurodegenerative diseases. Brain endothelial cells are crucial components of BBB. In the presen...
SUMO1 modification of 0N4R-tau is regulated by PIASx, SENP1, SENP2, and TRIM11 [0.03%]
PIASx、SENP1、SENP2和TRIM11调节0N4R-tau的SUMO1修饰
Harmony Wada,Takuma Maruyama,Takako Niikura
Harmony Wada
Tau is a microtubule-associated protein that contributes to cytoskeletal stabilization. Aggregation of tau proteins is associated with neurodegenerative disorders such as Alzheimer's disease. Several types of posttranslational modifications...
Corrigendum to "Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region" [Biochem. Biophys. Rep. 31 (2022) 1-9/101284] [0.03%]
关于“重新审视血清淀粉样A1蛋白错折叠倾向：重点关注信号肽区”的勘误(生物物理报告第31卷101284号，文章编号1-9(2022年))
Morgan S Haines,Eduardo Ramirez,Kendall B E Moore et al.
Morgan S Haines et al.
[This corrects the article DOI: 10.1016/j.bbrep.2022.101284.]. © 2022 The Author(s).
Published Erratum
Biochemistry and biophysics reports. 2024 Jul 16:39:101775. DOI:10.1016/j.bbrep.2024.101775 2024
Shahla Shojaei,Saeid Ghavami
Shahla Shojaei
New findings on the orientation of the mouse anterior-posterior (A-P) axis before and during the initiation of gastrulation using a more refined embryo staging [0.03%]
基于更精细的胚胎分期对小鼠头尾轴在致芽数日前后的新的研究进展
Xenia Hadjikypri,Christina Theofanous,Antonia Christodoulidi et al.
Xenia Hadjikypri et al.
A clinically significant event of early mammalian embryogenesis is the generation and early development of the anterior-posterior (A-P) axis, the imaginary line along which the structures from head to tail will form. This axis not only appe...
A comparative study of the efficacy of alginate lyases in the presence of metal ions elevated in the cystic fibrosis lung milieu [0.03%]
金属离子存在下评估硫酸盐化藻酸盐裂解酶在囊性纤维化肺部环境中的活性及效率
Neetu,T N C Ramya
Neetu
Pseudomonas aeruginosa, a common cause of morbidity in cystic fibrosis, chronically infects the patient's lungs by forming an alginate-containing biofilm. Alginate lyases are polysaccharide lyases that lyse alginate and are, therefore, pote...
microRNA profile of endometrial cancer from Indian patients-identification of potential biomarkers for prognosis [0.03%]
印度子宫内膜癌患者microRNA谱特征及潜在预后标志物的鉴定
Shraddha Hegde,Kalpesh Wagh,Suma Mysore Narayana et al.
Shraddha Hegde et al.
Endometrial cancer is one of the major cancers in women throughout the world. If diagnosed early, these cancers are treatable and the prognosis is usually good. However, one major problem in treating endometrial cancer is accurate diagnosis...
PIK3CA mutation analysis in circulating tumor cells of patients with hormone receptor positive metastatic breast cancer [0.03%]
激素受体阳性转移性乳腺癌患者循环肿瘤细胞中PIK3CA突变分析
Elena Marino,Cristian Mauro,Elena Belloni et al.
Elena Marino et al.
In metastatic breast cancer (MBC), blood is a source of circulating tumor cells (CTCs). CTCs may serve as a ''real-time liquid biopsy" as they represent metastatic tumor genetics better than primary tumor. PIK3CA is one of the most importan...
Advancements in Chronic Myeloid Leukemia detection: Development and evaluation of a novel QCM aptasensor for use in clinical practice [0.03%]
慢性粒细胞白血病检测新进展——临床诊疗用新型石英晶体微天平适配体传感器的开发及评估研究
Michaela Domsicova,Simona Kurekova,Andrea Babelova et al.
Michaela Domsicova et al.
Oncological diseases represent a significant global health challenge, with high mortality rates. Early detection is crucial for effective treatment, and aptamers, which demonstrate superior specificity and stability compared to antibodies, ...
In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue [0.03%]
血管内皮细胞通透性介导因素及抗血管内皮生长因子治疗重度登革热的潜在作用机制的体外研究分析
Sheng Jye Lim,Seng Chiew Gan,Hooi Tin Ong et al.
Sheng Jye Lim et al.
Background: Vascular endothelial growth factor (VEGF) is one of the proteins involved in dengue immunopathogenesis. It is overexpressed in severe dengue and contributes to vascular permeability and plasma leakage. In this...