"Protective effects of artichoke extract and Bifidobacterium longum on male infertility in diabetic rats" [0.03%]
洋蓟提取物及长双歧杆菌对糖尿病雄鼠生育力的保护作用
Zahra Ansari,Mohammad Hasan Maleki,Fatemeh Roohy et al.
Zahra Ansari et al.
Background: Diabetes is a major global health concern and plays a significant role in male infertility and hormonal abnormalities by altering the tissue structure of spermatogenic tubes and decreasing the number of sperma...
Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling [0.03%]
Cdc42、Rac1或RhoA的耗竭可降低PDGF诱导的STAT1和STAT3信号转导
Erik Wåhlén,Johan Lennartsson,Johan Heldin
Erik Wåhlén
This study investigates the role of Rho GTPases, specifically Cdc42, Rac1, and RhoA, in platelet-derived growth factor receptors (PDGFRα and PDGFRβ) signaling. Signal transducer and activator of transcription (STAT) proteins, essential fo...
Unveiling functionality and conducting two-sample mendelian randomization on WGCNA-identified oxidative stress-related hub genes in metabolic dysfunction-associated fatty liver disease [0.03%]
基于WGCNA鉴定的代谢功能异常相关脂肪肝病氧化应激关键基因的功能解析及两样本孟德尔随机化分析
Qian Zhu,Jiaqi Liu,Wuxuan Mei et al.
Qian Zhu et al.
Metabolic dysfunction-associated fatty liver disease (MAFLD) shows accelerated development under the impact of oxidative stress (OS). There is an imperative to identify OS-related biomarkers in MAFLD and explore their potential mechanistic ...
Kaja Karaś,Joanna Pastwińska,Anna Sałkowska et al.
Kaja Karaś et al.
Mutations in the ganglioside-induced differentiation-associated protein 1 (GDAP1) gene are linked to Charcot-Marie-Tooth (CMT) disease, a hereditary neurodegenerative condition. The protein encoded by this gene is involved in mitochondrial ...
The role of alveolar macrophages in viral respiratory infections and their therapeutic implications [0.03%]
肺泡巨噬细胞在病毒性呼吸道感染中的作用及其治疗意义
Atefe Panahipoor Javaherdehi,Somayyeh Ghanbari,Pooya Mahdavi et al.
Atefe Panahipoor Javaherdehi et al.
Alveolar macrophages are pivotal components of the lung's innate immune defense against respiratory virus infections. Their multifaceted role spans from viral clearance to modulation of immune responses, making them essential players in sha...
Exogenous interactome analysis of bovine viral diarrhea virus-host using network based-approach and identification of hub genes and important pathways involved in virus pathogenesis [0.03%]
基于网络的分析方法研究牛病毒性腹泻病毒与宿主互作组并鉴定参与病毒发病机制的关键基因和重要通路
Seyedeh Elham Rezatofighi
Seyedeh Elham Rezatofighi
Bovine viral diarrhea (BVD) is one of the most important diseases in livestock, caused by BVD virus (BVDV). During the pathogenesis of the virus, many interactions occur between host and viral proteins. Studying these interactions can help ...
Identifying molecular targets for modulating carotenoid accumulation in rice grains [0.03%]
识别调控水稻米粒类胡萝卜素积累的分子靶标
Rakshana Palaniswamy,Rohit Kambale,Vignesh Mohanavel et al.
Rakshana Palaniswamy et al.
Carotenoids are potential antioxidants offering extensive human health benefits including protection against chronic diseases. Augmenting the supply of health-benefiting compounds/metabolites through dietary supplements is the most sustaina...
Altered fatty acid distribution in lysosome-associated membrane protein-2 deficient mice [0.03%]
溶酶体相关膜蛋白-2缺陷型小鼠脂肪酸分布异常
Ziming Xu,Shoji Notomi,Guannan Wu et al.
Ziming Xu et al.
Lysosome-associated membrane protein-2 (LAMP2) deficiency causes the human Danon disease and represents a lysosomal dysfunction because of its pivotal role in regulating autophagy and lysosome biogenesis. LAMP2-deficient mice exhibit a spec...
Asparagus racemosus silver chloride nanoparticles and Kaempferia rotunda mediated silver/silver chloride nanoparticles inhibit human hepatocellular and lung cancer cell lines [0.03%]
银/氯化银纳米颗粒抑制人类肝细胞和肺癌细胞系
Syed Rashel Kabir,Mohammad Taufiq Alam,Md Belal Uddin
Syed Rashel Kabir
Recently, we have reported that biogenic silver/silver chloride nanoparticles from Asparagus racemosus (A. racemosus-AgCl-NPs) and Kaempferia rotunda (K. rotunda-Ag/AgCl-NPs) inhibited different cancer cells by inducing apoptosis and severa...
Development of specific anti-mouse atypical chemokine receptor 4 monoclonal antibodies [0.03%]
特异性抗小鼠非典型趋化因子受体4单克隆抗体的开发
Miu Hirose,Hiroyuki Suzuki,Rena Ubukata et al.
Miu Hirose et al.
Leukocyte migration is an essential function of innate and adaptive immune responses. Chemokines and their receptors control the migration system. The abundance of chemokines is controlled by atypical chemokine receptors (ACKRs), chemokine ...